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01-12-2016

Diagnostic yield of endoscopic ultrasonography-guided single-incision needle knife biopsy for gastric subepithelial tumors: comparison with resected specimens

Authors: Joon Sung Kim, Byung-Wook Kim, Gi Jun Kim, Young Wook Kim, Seung Ji Ryu, Sung Min Park, Jeong-Seon Ji, Sun Young Jun

Published in: Surgical Endoscopy | Issue 12/2016

Abstract

Background

Several techniques are recommended for the histologic diagnosis of gastric subepithelial tumors (SETs). The purpose of our study was to evaluate the diagnostic yield and safety of endoscopic ultrasonography-guided single-incision needle knife (SINK) biopsy for the diagnosis of gastric SETs.

Methods

A retrospective review of patients who received biopsy for gastric SETs from August 2012 to May 2015 was conducted. Patients who received endoscopic ultrasonography and were found to have a SET originating from the muscularis propria of the stomach were included in the study. The aim of our study was to investigate the safety and diagnostic yield of SINK biopsy for gastric SETs.

Results

A total of 31 patients received SINK biopsy for SETs. The diagnostic yield of SINK biopsy was 87 % (95 % CI 75–100 %), and the diagnostic accuracy was 89 % (95 % CI 74–105 %). The sensitivity of SINK biopsy to identify gastrointestinal stromal tumors was 83 % (95 % CI 52–98 %); the specificity was 100 % (95 % CI 59–100 %); the positive predictive value was 100 % (95 % CI 69–100 %); and the negative predictive value was 78 % (95 % CI 40–97 %). There were no procedure-related adverse events during and after procedure.

Conclusion

The use of SINK biopsy technique in patients with SETs is a good diagnostic tool with high diagnostic yield and accuracy. The method is simple, safe, and associated with few complications.

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Title: Diagnostic yield of endoscopic ultrasonography-guided single-incision needle knife biopsy for gastric subepithelial tumors: comparison with resected specimens
Authors: Joon Sung Kim
Byung-Wook Kim
Gi Jun Kim
Young Wook Kim
Seung Ji Ryu
Sung Min Park
Jeong-Seon Ji
Sun Young Jun
Publication date: 01-12-2016
Publisher: Springer US
Published in: Surgical Endoscopy / Issue 12/2016
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-016-4880-3

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Diagnostic yield of endoscopic ultrasonography-guided single-incision needle knife biopsy for gastric subepithelial tumors: comparison with resected specimens

Abstract

Background

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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