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Published in: Surgical Endoscopy 12/2016

01-12-2016

Long-term efficacy of modified retrievable stents for treatment of achalasia cardia

Authors: Jun Dai, Yufeng Shen, Xiaobo Li, Yunjie Gao, Yan Song, Zhizheng Ge

Published in: Surgical Endoscopy | Issue 12/2016

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Abstract

Aim

To investigate the efficacy, safety and optimal duration of placement of modified retrievable metal stents for treatment of achalasia cardia.

Methods

Patients were randomly divided into groups A (N = 26, modified stents for 3 days), B (N = 26, modified stents for 2 days), C (N = 24, balloon dilation), and D (N = 25, regular stents for 2 days). Clinical symptom scores were recorded at baseline, 6 months, and during long-term follow-up.

Results

Seventy-seven patients with achalasia underwent stent placement (100 % success rate of implantation and extraction, no perforation). No stent migration or drop-off occurred in groups A and B. In group D, stent drop-off and migration was observed in 2 and 1 patients, respectively. Two patients in group C sustained esophageal perforation. Patients in the modified stent (A and B), balloon dilated (C) and regular stents (D) groups experienced significant improvement in dysphagia at 6 months, with recurrence in 1.92, 8.33 and 28 %, respectively. The clinical symptom score in the modified stent groups was significantly lower than that in the balloon dilated group (P = 0.01). During long-term follow-up, the symptom scores in modified stent groups were significantly lower than that in the balloon dilated (P < 0.01) and regular stent (P < 0.01) groups.

Conclusion

Modified retrievable metal stents required an optimal placement duration of 2 days were safe with no incidence of migration or drop-off and had a lower recurrence of symptoms.
Literature
1.
go back to reference Vaezi MF, Richter JE (1999) Diagnosis and management of achalasia. American College of Gastroenterology Practice Parameter Committee. Am J Gastroenterol 94:3406–3412CrossRefPubMed Vaezi MF, Richter JE (1999) Diagnosis and management of achalasia. American College of Gastroenterology Practice Parameter Committee. Am J Gastroenterol 94:3406–3412CrossRefPubMed
2.
go back to reference Francis DL, Katzka DA (2010) Achalasia: update on the disease and its treatment. Gastroenterology 139:369–374CrossRefPubMed Francis DL, Katzka DA (2010) Achalasia: update on the disease and its treatment. Gastroenterology 139:369–374CrossRefPubMed
3.
go back to reference Eckardt VF (2001) Clinical presentations and complications of achalasia. Gastrointest Endosc Clin N Am 11(2):281–292PubMed Eckardt VF (2001) Clinical presentations and complications of achalasia. Gastrointest Endosc Clin N Am 11(2):281–292PubMed
4.
go back to reference Hulselmans M, Vanuytsel T, Degreef T, Sifrim D, Coosemans W, Lerut T, Tack J (2010) Long-term outcome of pneumatic dilation in the treatment of achalasia. Clin Gastroenterol Hepatol 8:30–35CrossRefPubMed Hulselmans M, Vanuytsel T, Degreef T, Sifrim D, Coosemans W, Lerut T, Tack J (2010) Long-term outcome of pneumatic dilation in the treatment of achalasia. Clin Gastroenterol Hepatol 8:30–35CrossRefPubMed
5.
go back to reference Vela MF, Richter JE, Khandwala F, Blackstone EH, Wachsberger D, Baker ME, Rice TW (2006) The long-term efficacy of pneumatic dilatation and Heller myotomy for the treatment of achalasia. Clin Gastroenterol Hepatol 4:580–587CrossRefPubMed Vela MF, Richter JE, Khandwala F, Blackstone EH, Wachsberger D, Baker ME, Rice TW (2006) The long-term efficacy of pneumatic dilatation and Heller myotomy for the treatment of achalasia. Clin Gastroenterol Hepatol 4:580–587CrossRefPubMed
6.
go back to reference Campos GM, Vittinghoff E, Rabl C et al (2009) Endoscopic and surgical treatments for achalasia: a systematic review and meta-analysis. Ann Surg 249:45–57CrossRefPubMed Campos GM, Vittinghoff E, Rabl C et al (2009) Endoscopic and surgical treatments for achalasia: a systematic review and meta-analysis. Ann Surg 249:45–57CrossRefPubMed
7.
go back to reference Wang L, Li YM, Li L (2009) Meta-analysis of randomized and controlled treatment trials for achalasia. Dig Dis Sci 54:2303–2311CrossRefPubMed Wang L, Li YM, Li L (2009) Meta-analysis of randomized and controlled treatment trials for achalasia. Dig Dis Sci 54:2303–2311CrossRefPubMed
8.
go back to reference Wang L, Li YM, Li L et al (2008) A systematic review and meta-analysis of the Chinese literature for the treatment of achalasia. World J Gastroenterol 14:5900–5906CrossRefPubMedPubMedCentral Wang L, Li YM, Li L et al (2008) A systematic review and meta-analysis of the Chinese literature for the treatment of achalasia. World J Gastroenterol 14:5900–5906CrossRefPubMedPubMedCentral
9.
go back to reference Jones EL, Meara MP, Pittman MR, Hazey JW, Perry KA (2016) Prior treatment does not influence the performance or early outcome of per-oral endoscopic myotomy for achalasia. Surg Endosc 30(4):1282–1286CrossRefPubMed Jones EL, Meara MP, Pittman MR, Hazey JW, Perry KA (2016) Prior treatment does not influence the performance or early outcome of per-oral endoscopic myotomy for achalasia. Surg Endosc 30(4):1282–1286CrossRefPubMed
10.
go back to reference Friedel D, Modayil R, Iqbal S, Grendell JH, Stavropoulos SN (2013) Per-oral endoscopic myotomy for achalasia: an American perspective. World J Gastrointest Endosc 5:420–427CrossRefPubMedPubMedCentral Friedel D, Modayil R, Iqbal S, Grendell JH, Stavropoulos SN (2013) Per-oral endoscopic myotomy for achalasia: an American perspective. World J Gastrointest Endosc 5:420–427CrossRefPubMedPubMedCentral
11.
go back to reference Verlaan T, Rohof WO, Bredenoord AJ, Eberl S, Rösch T, Fockens P (2013) Effect of peroral endoscopic myotomy on esophagogastric junction physiology in patients with achalasia. Gastrointest Endosc 78:39–44CrossRefPubMed Verlaan T, Rohof WO, Bredenoord AJ, Eberl S, Rösch T, Fockens P (2013) Effect of peroral endoscopic myotomy on esophagogastric junction physiology in patients with achalasia. Gastrointest Endosc 78:39–44CrossRefPubMed
12.
go back to reference Von Renteln D, Fuchs KH, Fockens P, Bauerfeind P, Vassiliou MC, Werner YB, Fried G, Breithaupt W, Heinrich H, Bredenoord AJ, Kersten JF, Verlaan T, Trevisonno M, Rösch T (2013) Peroral endoscopic myotomy for the treatment of achalasia: an international prospective multicenter study. Gastroenterology 145:309–311CrossRef Von Renteln D, Fuchs KH, Fockens P, Bauerfeind P, Vassiliou MC, Werner YB, Fried G, Breithaupt W, Heinrich H, Bredenoord AJ, Kersten JF, Verlaan T, Trevisonno M, Rösch T (2013) Peroral endoscopic myotomy for the treatment of achalasia: an international prospective multicenter study. Gastroenterology 145:309–311CrossRef
13.
go back to reference Zhao JG, Li YD, Cheng YS et al (2009) Long term safety and outcome of a temporary self-expanding metallic stent for achalasia: prospective study with a 13 year single center experience. Eur Radiol 19:1973–1980CrossRefPubMedPubMedCentral Zhao JG, Li YD, Cheng YS et al (2009) Long term safety and outcome of a temporary self-expanding metallic stent for achalasia: prospective study with a 13 year single center experience. Eur Radiol 19:1973–1980CrossRefPubMedPubMedCentral
14.
go back to reference Athanasios DS, Chrysoula M, George DD et al (2015) Self-expandable metal stents for achalasia: thinking out of box. World J Gastrointest Endosc 7:45–52CrossRef Athanasios DS, Chrysoula M, George DD et al (2015) Self-expandable metal stents for achalasia: thinking out of box. World J Gastrointest Endosc 7:45–52CrossRef
15.
go back to reference Cai XB, Dai YM, Zhou H et al (2013) Comparison between botulinum injection and removable covered self-expanding metal stents for the treatment of achalasia. Dig Dis Sci 58:1960–1966CrossRefPubMed Cai XB, Dai YM, Zhou H et al (2013) Comparison between botulinum injection and removable covered self-expanding metal stents for the treatment of achalasia. Dig Dis Sci 58:1960–1966CrossRefPubMed
16.
go back to reference Chen YS, Ma F, Wu CG et al (2010) Temporary self-expanding metallic stents for achalasia: a prospective study with a long-term follow-up. World J Gastrointest Endosc 16:5110–5117 Chen YS, Ma F, Wu CG et al (2010) Temporary self-expanding metallic stents for achalasia: a prospective study with a long-term follow-up. World J Gastrointest Endosc 16:5110–5117
17.
go back to reference Dai J, Shen YF, Ge ZZ et al (2012) Efficacy of implantation of a modified temporary metallic stent for cardia achalasia. Chin J Dig Endosc 29:19–23 Dai J, Shen YF, Ge ZZ et al (2012) Efficacy of implantation of a modified temporary metallic stent for cardia achalasia. Chin J Dig Endosc 29:19–23
18.
go back to reference Yaghoobi M, Mikaeli J, Montazeri G et al (2003) Correlation between clinical severity score and the lower esophageal sphincter relaxation pressure in idiopathic achalasia. Am J Gastroenterol 98:278–283CrossRefPubMed Yaghoobi M, Mikaeli J, Montazeri G et al (2003) Correlation between clinical severity score and the lower esophageal sphincter relaxation pressure in idiopathic achalasia. Am J Gastroenterol 98:278–283CrossRefPubMed
19.
go back to reference Diaz RAB, Sampascual SB, Calderon AJ et al (2009) Self-expanding esophageal prostheses as an alternative temporary treatment for achalasia. Gastrointest Endosc 69(4):980CrossRef Diaz RAB, Sampascual SB, Calderon AJ et al (2009) Self-expanding esophageal prostheses as an alternative temporary treatment for achalasia. Gastrointest Endosc 69(4):980CrossRef
20.
go back to reference Werner YB, Costamagna G, Swanstrom LL et al (2015) Clinical response to peroral endoscopic myotomy in patients with idiopathic achalasia at a minimum follow-up of 2 years. Gut 0:1–8 (Gut Online first, published on April 30, 2015) Werner YB, Costamagna G, Swanstrom LL et al (2015) Clinical response to peroral endoscopic myotomy in patients with idiopathic achalasia at a minimum follow-up of 2 years. Gut 0:1–8 (Gut Online first, published on April 30, 2015)
Metadata
Title
Long-term efficacy of modified retrievable stents for treatment of achalasia cardia
Authors
Jun Dai
Yufeng Shen
Xiaobo Li
Yunjie Gao
Yan Song
Zhizheng Ge
Publication date
01-12-2016
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 12/2016
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-016-4879-9

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