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Surgical Endoscopy
Published in: Surgical Endoscopy 10/2016

01-10-2016 | New Technology

A novel endoscopic fluorescent band ligation method for tumor localization

Authors: Jong Hee Hyun, Seok-Ki Kim, Kwang Gi Kim, Hong Rae Kim, Hyun Min Lee, Sunup Park, Sung Chun Kim, Yongdoo Choi, Dae Kyung Sohn

Published in: Surgical Endoscopy | Issue 10/2016

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Abstract

Background

Accurate tumor localization is essential for minimally invasive surgery. This study describes the development of a novel endoscopic fluorescent band ligation method for the rapid and accurate identification of tumor sites during surgery.

Methods and materials

The method utilized a fluorescent rubber band, made of indocyanine green (ICG) and a liquid rubber solution mixture, as well as a near-infrared fluorescence laparoscopic system with a dual light source using a high-powered light-emitting diode (LED) and a 785-nm laser diode. The fluorescent rubber bands were endoscopically placed on the mucosae of porcine stomachs and colons. During subsequent conventional laparoscopic stomach and colon surgery, the fluorescent bands were assayed using the near-infrared fluorescence laparoscopy system.

Results

The locations of the fluorescent clips were clearly identified on the fluorescence images in real time. The system was able to distinguish the two or three bands marked on the mucosal surfaces of the stomach and colon. Resection margins around the fluorescent bands were sufficient in the resected specimens obtained during stomach and colon surgery.

Conclusion

These novel endoscopic fluorescent bands could be rapidly and accurately localized during stomach and colon surgery. Use of these bands may make possible the excision of exact target sites during minimally invasive gastrointestinal surgery.
Appendix
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Literature
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Metadata
Title
A novel endoscopic fluorescent band ligation method for tumor localization
Authors
Jong Hee Hyun
Seok-Ki Kim
Kwang Gi Kim
Hong Rae Kim
Hyun Min Lee
Sunup Park
Sung Chun Kim
Yongdoo Choi
Dae Kyung Sohn
Publication date
01-10-2016
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 10/2016
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-016-4785-1

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