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01-04-2013

Laparoscopic versus open resection of colorectal liver metastasis

Authors: Alfredo D. Guerron, Shamil Aliyev, Orhan Agcaoglu, Erol Aksoy, Halit Eren Taskin, Federico Aucejo, Charles Miller, John Fung, Eren Berber

Published in: Surgical Endoscopy | Issue 4/2013

Abstract

Background

Findings have shown laparoscopic liver resection (LLR) to be feasible and safe, but the data in the literature regarding oncologic outcomes are scant. This study aimed to compare the perioperative and short-term oncologic outcomes between LLR and open resection of colorectal liver metastasis (CLM).

Methods

Between January 2006 and April 2012, 40 patients underwent LLR of CLM. These patients were compared with a consecutive matched group of 40 patients who underwent open resection within the same period. Data were obtained from a prospective institutional review board (IRB)-approved database. Statistical analysis was performed using t test, Chi-square, and Kaplan–Meier survival.

Results

The groups were similar in terms of age, gender, tumor size, number of tumors, and type of resections performed. The operative time was similar in the two groups, but the estimated blood loss was less in the LLR group than in the open resection group. The length of stay was shorter in the LLR group (3.7 vs 6.5 days; p < 0.001). The 2-year overall survival rate was 89 % for LLR and 81 % for open resection. The median disease-free survival time was 23 months in each group.

Conclusions

The findings suggest that LLR is associated with less blood loss and a shorter hospital stay than open resection for CLM. According to our short-term results, LLR is equivalent to open resection in terms of oncologic outcomes.

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Title: Laparoscopic versus open resection of colorectal liver metastasis
Authors: Alfredo D. Guerron
Shamil Aliyev
Orhan Agcaoglu
Erol Aksoy
Halit Eren Taskin
Federico Aucejo
Charles Miller
John Fung
Eren Berber
Publication date: 01-04-2013
Publisher: Springer-Verlag
Published in: Surgical Endoscopy / Issue 4/2013
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-012-2563-2

At a glance: The STEP trials

Springer Medicine

Laparoscopic versus open resection of colorectal liver metastasis

Abstract

Background

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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