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Published in: Surgical Endoscopy 10/2011

01-10-2011

Long-term outcomes of laparoscopic surgery versus open resection for middle and lower rectal cancer: an NTCLES study

Authors: Shaotang Li, Pan Chi, Huiming Lin, Xingrong Lu, Ying Huang

Published in: Surgical Endoscopy | Issue 10/2011

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Abstract

Background

Prognoses for treatment of middle and lower rectal cancer remain unclear because anatomical and complex surgical procedures specifically influence long-term outcomes. This study analyzes the long-term outcomes of laparoscopic versus open resection for middle and lower rectal cancer.

Methods

Patients (laparoscopic, n = 113; open, n = 123) who underwent curative resection for middle and lower rectal cancer from 2000 to 2005 participated in the study. All operations were performed by the same surgical team with extensive experience in laparoscopic and open procedures. The mean follow-up time of all patients was 74.8 months.

Results

No statistical differences in local recurrence rate (9.1% vs. 6.4%; log-rank = 0.432; p = 0.511) and in distant recurrence rate (19.7% vs. 15.5%; log-rank = 0.505; p = 0.477) between laparoscopic and open groups were observed within 5 years. The 5-year overall survival rates of the laparoscopic and open groups were 77.9 and 78.9%, respectively; no significant statistical difference was observed between them (log-rank = 0.012; p = 0.913). The 5-year survival rates between groups were not different between stages: stage I (91.7% vs. 92.0%; p = 0.950), stage II (82.8% vs. 79.4%; p = 0.643), and stage III (66.7% vs. 70.3%; p = 0.850). However, significant statistical differences between different stages were observed (log-rank = 11.156; p = 0.004).

Conclusion

Laparoscopic and open surgery for middle and lower rectal cancer offer similar long-term outcomes. The continued use of laparoscopic surgery in these patients can be supported.
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Metadata
Title
Long-term outcomes of laparoscopic surgery versus open resection for middle and lower rectal cancer: an NTCLES study
Authors
Shaotang Li
Pan Chi
Huiming Lin
Xingrong Lu
Ying Huang
Publication date
01-10-2011
Publisher
Springer-Verlag
Published in
Surgical Endoscopy / Issue 10/2011
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-011-1683-4

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