Skip to main content
Top
Published in: Surgical Endoscopy 3/2009

01-03-2009

Outcome of surgical fundoplication for extra-oesophageal symptoms of reflux

Authors: Mohd Iqbal, A. J. Batch, Krishna Moorthy, B. T. Cooper, R. T. Spychal

Published in: Surgical Endoscopy | Issue 3/2009

Login to get access

Abstract

Background

The role of surgery in the management of extra-oesophageal symptoms of gastro-oesophageal reflux (EOR) is unclear. In this retrospective study we studied patients who had surgical fundoplication for EOR symptoms from 1995 to 2005. We analysed outcome with respect to symptomatic improvement and patient satisfaction.

Methods

From our database of 240 patients who had surgical fundoplication for gastro-oesophageal reflux disease, 51 patients who had predominantly EOR symptoms were identified. All the patients had objective evidence of reflux and had been offered surgery because of failure of medical therapy and/or of development of complications.
Patients were asked to score their symptoms before and after surgery using the Reflux Symptom Index, and to record their use of medicine before and after operation, their experience with surgery and their overall quality of life using a written questionnaire.

Results

Forty of the 51 patients were available for analysis. Common symptoms were cough and breathlessness (32/40), throat clearing/postnasal drip (31/40), sensation of lump in the throat (29/40), and voice problems (22/40). Of these forty patients, 34 (85%) had associated classical symptoms as well. Mean follow up at the time of questionnaire was 53.3 (6–120) months. The mean Reflux Symptom Index score improved from 22.80 (SD 10.80) to 11.83 (SD 9.91) (p < 0.0001, paired t-test).
Six of the 39 responders (15.3%) said they would not have had the operation knowing what they know now and that problems related to the operation outweighed any benefits. These problems included gas bloating, inability to retch and dysphagia lasting up to one year after surgery. Twenty-five percent of the 40 patients described their overall quality of life as excellent, 32.5% as good, 32.5% as satisfactory and 10% as bad.

Conclusion

Surgery can be an effective treatment in the majority of patients with extra-oesophageal symptoms of reflux.
Literature
1.
go back to reference Allen CJ, Anvari M (2002) Preoperative symptom evaluation and esophageal acid infusion predict response to laparoscopic Nissen fundoplication in gastro-esophageal reflux patients who present with cough. Surg Endosc 16:1037–1041PubMedCrossRef Allen CJ, Anvari M (2002) Preoperative symptom evaluation and esophageal acid infusion predict response to laparoscopic Nissen fundoplication in gastro-esophageal reflux patients who present with cough. Surg Endosc 16:1037–1041PubMedCrossRef
2.
go back to reference Belfasky PC, Postma GN, Amin MR, Koufman JA (2002) Symptoms and findings of laryngopharyngeal reflux. Ear Nose Throat J 81:10–13 Belfasky PC, Postma GN, Amin MR, Koufman JA (2002) Symptoms and findings of laryngopharyngeal reflux. Ear Nose Throat J 81:10–13
3.
go back to reference Drug VL, Cobzeanu D, Papaghuic C et al (2005) Gastro-oesophageal reflux involvement in ENT disorders. Rev Med Chir Soc Med Nat Iasi 109:220–222PubMed Drug VL, Cobzeanu D, Papaghuic C et al (2005) Gastro-oesophageal reflux involvement in ENT disorders. Rev Med Chir Soc Med Nat Iasi 109:220–222PubMed
4.
go back to reference Duffy JP Maggard M, Hiyama DT, Atkinson JB (2003) Laparoscopic Nissen fundoplication improves quality of life in patients with atypical symptoms of gastro-esophageal reflux. Am Surg 69:833–838 Duffy JP Maggard M, Hiyama DT, Atkinson JB (2003) Laparoscopic Nissen fundoplication improves quality of life in patients with atypical symptoms of gastro-esophageal reflux. Am Surg 69:833–838
5.
go back to reference Farrel TM, Richardson WS, Trus TL, Smith CD, Hunter JG (2001) Response of atypical symptoms of gastro-oesophageal reflux to antireflux surgery. Br J Surg 88:1649–1652CrossRef Farrel TM, Richardson WS, Trus TL, Smith CD, Hunter JG (2001) Response of atypical symptoms of gastro-oesophageal reflux to antireflux surgery. Br J Surg 88:1649–1652CrossRef
6.
go back to reference Fernando HC, El-Sherif Amgad, Landreneau JR, Gilbert S et al (2005) Efficacy of laparoscopic fundoplication in controlling pulmonary symptoms associated with gastro-esophageal reflux disease. Surgery 138:612–617 Fernando HC, El-Sherif Amgad, Landreneau JR, Gilbert S et al (2005) Efficacy of laparoscopic fundoplication in controlling pulmonary symptoms associated with gastro-esophageal reflux disease. Surgery 138:612–617
7.
go back to reference Fuchs KH, DeMeester TR, Albertucci M (1987) Specificity and sensitivity of objective diagnosis of gastro-esophageal reflux disease. Surgery 102:575–580PubMed Fuchs KH, DeMeester TR, Albertucci M (1987) Specificity and sensitivity of objective diagnosis of gastro-esophageal reflux disease. Surgery 102:575–580PubMed
8.
go back to reference Gadenstatter M, Wykypiel, Schwab GP, Profanter C, Wetscher GJ (1999) Respiratory symptoms and dysphagia in patients with gastro-oesophageal reflux disease: a comparison of medical and surgical therapy. Langenbach’s Arch Surg 384:563–567 Gadenstatter M, Wykypiel, Schwab GP, Profanter C, Wetscher GJ (1999) Respiratory symptoms and dysphagia in patients with gastro-oesophageal reflux disease: a comparison of medical and surgical therapy. Langenbach’s Arch Surg 384:563–567
9.
go back to reference James BY, Zeitels SM, Rattner DW (1998) Outcomes of atypical symptoms attributed to gastro-oesophageal reflux treated by laparoscopic fundoplication. Surgery 124:28–32 James BY, Zeitels SM, Rattner DW (1998) Outcomes of atypical symptoms attributed to gastro-oesophageal reflux treated by laparoscopic fundoplication. Surgery 124:28–32
10.
go back to reference Johnson WE, Hagen JA, Demeester TR et al (1996) Outcome of respiratory symptoms after antireflux surgery on patients with gastro-esophageal reflux. Arch Surg 31:489–492 Johnson WE, Hagen JA, Demeester TR et al (1996) Outcome of respiratory symptoms after antireflux surgery on patients with gastro-esophageal reflux. Arch Surg 31:489–492
11.
go back to reference Novitsky YW, Zawacki JK, Irwin RS et al (2002) Chronic cough due to gastro-oesophageal reflux disease Efficacy of antireflux surgery. Surg Endosc 16:567–571PubMedCrossRef Novitsky YW, Zawacki JK, Irwin RS et al (2002) Chronic cough due to gastro-oesophageal reflux disease Efficacy of antireflux surgery. Surg Endosc 16:567–571PubMedCrossRef
12.
go back to reference Poelmans J, Feenstra L, Tack J (2006) Determinants of long term outcome of patients with reflux related ear, nose and throat symptoms. Dig Dis Sci 51:282–288PubMedCrossRef Poelmans J, Feenstra L, Tack J (2006) Determinants of long term outcome of patients with reflux related ear, nose and throat symptoms. Dig Dis Sci 51:282–288PubMedCrossRef
13.
go back to reference Rakita S, Villadolid D, Thomas A, Bloomstan M, Albrinck M, Goldin S (2006) Laparoscopic Nissen fundoplication offers high patient satisfaction with relief of extra-esophageal symptoms of gastro-esophageal reflux disease. Am Surg 72:207–212PubMed Rakita S, Villadolid D, Thomas A, Bloomstan M, Albrinck M, Goldin S (2006) Laparoscopic Nissen fundoplication offers high patient satisfaction with relief of extra-esophageal symptoms of gastro-esophageal reflux disease. Am Surg 72:207–212PubMed
14.
go back to reference Richter JE (1998) Extra-oesophageal presentations of gastroesophageal reflux disease. Semin Gastrointest Dis 8:75–89 Richter JE (1998) Extra-oesophageal presentations of gastroesophageal reflux disease. Semin Gastrointest Dis 8:75–89
15.
go back to reference Sarela AI, Verbeke CS, Pring C, Guillou PJ (2004) Is symptom control the correct end point for proton pump inhibitor treatment in Barrets oesophagus? Gut 53:1387–1388PubMedCrossRef Sarela AI, Verbeke CS, Pring C, Guillou PJ (2004) Is symptom control the correct end point for proton pump inhibitor treatment in Barrets oesophagus? Gut 53:1387–1388PubMedCrossRef
16.
go back to reference Westcott CJ, Hopkins MB, Bach K, Postma GN, Belafsky PC, Koufman JA (2004) Fundoplication for laryngopharyngeal reflux disease. J Am Coll Surg 199:23–30PubMedCrossRef Westcott CJ, Hopkins MB, Bach K, Postma GN, Belafsky PC, Koufman JA (2004) Fundoplication for laryngopharyngeal reflux disease. J Am Coll Surg 199:23–30PubMedCrossRef
Metadata
Title
Outcome of surgical fundoplication for extra-oesophageal symptoms of reflux
Authors
Mohd Iqbal
A. J. Batch
Krishna Moorthy
B. T. Cooper
R. T. Spychal
Publication date
01-03-2009
Publisher
Springer-Verlag
Published in
Surgical Endoscopy / Issue 3/2009
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-008-9861-8

Other articles of this Issue 3/2009

Surgical Endoscopy 3/2009 Go to the issue