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Published in: Surgical Endoscopy 5/2008

01-05-2008

Factors associated with prolonged stay after laparoscopic cholecystectomy in elderly patients

Authors: Shih-Ping Cheng, Yuan-Ching Chang, Chien-Liang Liu, Tsen-Long Yang, Kuo-Shyang Jeng, Jie-Jen Lee, Tsang-Pai Liu

Published in: Surgical Endoscopy | Issue 5/2008

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Abstract

Background

Laparoscopic cholecystectomy in elderly patients has been linked to higher complication rates and longer lengths of stay. The purpose of this study was to identify risk factors associated with prolonged postoperative hospitalization in elderly patients undergoing laparoscopic cholecystectomy.

Methods

The records of 287 patients aged 65 years or older, who underwent successful laparoscopic cholecystectomy between January 2001 and July 2006, were retrospectively reviewed. Clinical data was abstracted from the chart and compared between patients with a shorter or longer postoperative stay.

Results

The median postoperative hospital stay was three days (interquartile range 3–5). Forty-eight patients had complications, with an overall morbidity of 16% and mortality of 0.7%. The only independent predictor of prolonged postoperative stay was the occurrence of any major complication [odds ratio, 3.144; 95% confidence interval (CI), 1.882–5.251]. The physiological and operative severity score for the enumeration of mortality and morbidity (POSSUM) and underlying chronic obstructive pulmonary disease were independently associated with major complications.

Conclusions

A major complication is the most important cause of prolonged hospital stay after laparoscopic cholecystectomy in the elderly. No specific comorbidity has direct impact on the duration of hospitalization, but pulmonary disease is associated with increased risk of major complications.
Literature
1.
go back to reference Ratner J, Lisbona A, Rosenbloom M, Palayew M, Szabolcsi S, Tupaz T (1991) The prevalence of gallstone disease in very old institutionalized persons. JAMA 265:902–903PubMedCrossRef Ratner J, Lisbona A, Rosenbloom M, Palayew M, Szabolcsi S, Tupaz T (1991) The prevalence of gallstone disease in very old institutionalized persons. JAMA 265:902–903PubMedCrossRef
2.
go back to reference Morrow DJ, Thompson J, Wilson SE (1978) Acute cholecystitis in the elderly: a surgical emergency. Arch Surg 113:1149–1152PubMedCrossRef Morrow DJ, Thompson J, Wilson SE (1978) Acute cholecystitis in the elderly: a surgical emergency. Arch Surg 113:1149–1152PubMedCrossRef
3.
go back to reference Sauerland S, Agresta F, Bergamaschi R, Borzellino G, Budzynski A, Champault G, Fingerhut A, Isla A, Johansson M, Lundorff P, Navez B, Saad S, Neugebauer EA (2006) Laparoscopy for abdominal emergencies: evidence-based guidelines of the European Association for Endoscopic Surgery. Surg Endosc 20:14–29PubMedCrossRef Sauerland S, Agresta F, Bergamaschi R, Borzellino G, Budzynski A, Champault G, Fingerhut A, Isla A, Johansson M, Lundorff P, Navez B, Saad S, Neugebauer EA (2006) Laparoscopy for abdominal emergencies: evidence-based guidelines of the European Association for Endoscopic Surgery. Surg Endosc 20:14–29PubMedCrossRef
4.
go back to reference Roslyn JJ, Binns GS, Hughes EF, Saunders-Kirkwood K, Zinner MJ, Cates JA (1993) Open cholecystectomy. A contemporary analysis of 42,474 patients. Ann Surg 218:129–137PubMedCrossRef Roslyn JJ, Binns GS, Hughes EF, Saunders-Kirkwood K, Zinner MJ, Cates JA (1993) Open cholecystectomy. A contemporary analysis of 42,474 patients. Ann Surg 218:129–137PubMedCrossRef
5.
go back to reference Weber DM (2003) Laparoscopic surgery: an excellent approach in elderly patients. Arch Surg 138:1083–1088PubMedCrossRef Weber DM (2003) Laparoscopic surgery: an excellent approach in elderly patients. Arch Surg 138:1083–1088PubMedCrossRef
6.
go back to reference Turrentine FE, Wang H, Simpson VB, Jones RS (2006) Surgical risk factors, morbidity, and mortality in elderly patients. J Am Coll Surg 203:865–877PubMedCrossRef Turrentine FE, Wang H, Simpson VB, Jones RS (2006) Surgical risk factors, morbidity, and mortality in elderly patients. J Am Coll Surg 203:865–877PubMedCrossRef
7.
go back to reference Lujan JA, Sanchez-Bueno F, Parrilla P, Robles R, Torralba JA, Gonzalez-Costea R (1998) Laparoscopic vs. open cholecystectomy in patients aged 65 and older. Surg Laparosc Endosc 8:208–210PubMedCrossRef Lujan JA, Sanchez-Bueno F, Parrilla P, Robles R, Torralba JA, Gonzalez-Costea R (1998) Laparoscopic vs. open cholecystectomy in patients aged 65 and older. Surg Laparosc Endosc 8:208–210PubMedCrossRef
8.
go back to reference Kalish RL, Daley J, Duncan CC, Davis RB, Coffman GA, Iezzoni LI (1995) Costs of potential complications of care for major surgery patients. Am J Med Qual 10:48–54PubMedCrossRef Kalish RL, Daley J, Duncan CC, Davis RB, Coffman GA, Iezzoni LI (1995) Costs of potential complications of care for major surgery patients. Am J Med Qual 10:48–54PubMedCrossRef
9.
go back to reference Issa ME, Al-Rashedy M, Ballester P, Ammori BJ (2005) Predictors of duration of postoperative hospital stay in patients undergoing advanced laparoscopic surgery. Surg Laparosc Endosc Percutan Tech 15:90–93PubMedCrossRef Issa ME, Al-Rashedy M, Ballester P, Ammori BJ (2005) Predictors of duration of postoperative hospital stay in patients undergoing advanced laparoscopic surgery. Surg Laparosc Endosc Percutan Tech 15:90–93PubMedCrossRef
10.
go back to reference Jones K, DeCamp BS, Mangram AJ, Dunn EL (2005) Laparoscopic converted to open cholecystectomy minimally prolongs hospitalization. Am J Surg 190:879–881PubMed Jones K, DeCamp BS, Mangram AJ, Dunn EL (2005) Laparoscopic converted to open cholecystectomy minimally prolongs hospitalization. Am J Surg 190:879–881PubMed
11.
go back to reference Copeland GP, Jones D, Walters M (1991) POSSUM: a scoring system for surgical audit. Br J Surg 78:355–360PubMedCrossRef Copeland GP, Jones D, Walters M (1991) POSSUM: a scoring system for surgical audit. Br J Surg 78:355–360PubMedCrossRef
12.
go back to reference Charlson ME, Pompei P, Ales KL, MacKenzie CR (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373–383PubMedCrossRef Charlson ME, Pompei P, Ales KL, MacKenzie CR (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373–383PubMedCrossRef
13.
go back to reference Rozzini R, Frisoni GB, Ferrucci L, Barbisoni P, Sabatini T, Ranieri P, Guralnik JM, Trabucchi M (2002) Geriatric Index of Comorbidity: validation and comparison with other measures of comorbidity. Age Ageing 31:277–285PubMedCrossRef Rozzini R, Frisoni GB, Ferrucci L, Barbisoni P, Sabatini T, Ranieri P, Guralnik JM, Trabucchi M (2002) Geriatric Index of Comorbidity: validation and comparison with other measures of comorbidity. Age Ageing 31:277–285PubMedCrossRef
14.
go back to reference Clavien PA, Sanabria JR, Strasberg SM (1992) Proposed classification of complications of surgery with examples of utility in cholecystectomy. Surgery 111:518–526PubMed Clavien PA, Sanabria JR, Strasberg SM (1992) Proposed classification of complications of surgery with examples of utility in cholecystectomy. Surgery 111:518–526PubMed
15.
go back to reference Collins TC, Daley J, Henderson WH, Khuri SF (1999) Risk factors for prolonged length of stay after major elective surgery. Ann Surg 230:251–259PubMedCrossRef Collins TC, Daley J, Henderson WH, Khuri SF (1999) Risk factors for prolonged length of stay after major elective surgery. Ann Surg 230:251–259PubMedCrossRef
16.
go back to reference Bingener J, Richards ML, Schwesinger WH, Strodel WE, Sirinek KR (2003) Laparoscopic cholecystectomy for elderly patients: gold standard for golden years? Arch Surg 138:531–536PubMedCrossRef Bingener J, Richards ML, Schwesinger WH, Strodel WE, Sirinek KR (2003) Laparoscopic cholecystectomy for elderly patients: gold standard for golden years? Arch Surg 138:531–536PubMedCrossRef
17.
go back to reference Tambyraja AL, Kumar S, Nixon SJ (2004) Outcome of laparoscopic cholecystectomy in patients 80 years and older. World J Surg 28:745–748PubMedCrossRef Tambyraja AL, Kumar S, Nixon SJ (2004) Outcome of laparoscopic cholecystectomy in patients 80 years and older. World J Surg 28:745–748PubMedCrossRef
18.
19.
go back to reference Tambyraja AL, Kumar S, Nixon SJ (2005) POSSUM scoring for laparoscopic cholecystectomy in the elderly. ANZ J Surg 75:550–552PubMedCrossRef Tambyraja AL, Kumar S, Nixon SJ (2005) POSSUM scoring for laparoscopic cholecystectomy in the elderly. ANZ J Surg 75:550–552PubMedCrossRef
20.
21.
go back to reference Cooper GS, Shlaes DM, Salata RA (1994) Intraabdominal infection: differences in presentation and outcome between younger patients and the elderly. Clin Infect Dis 19:146–148PubMedCrossRef Cooper GS, Shlaes DM, Salata RA (1994) Intraabdominal infection: differences in presentation and outcome between younger patients and the elderly. Clin Infect Dis 19:146–148PubMedCrossRef
22.
go back to reference Burns LR, Wholey DR (1991) The effects of patient, hospital, and physician characteristics on length of stay and mortality. Med Care 29:251–271PubMedCrossRef Burns LR, Wholey DR (1991) The effects of patient, hospital, and physician characteristics on length of stay and mortality. Med Care 29:251–271PubMedCrossRef
23.
go back to reference Polanczyk CA, Marcantonio E, Goldman L, Rohde LE, Orav J, Mangione CM, Lee TH (2001) Impact of age on perioperative complications and length of stay in patients undergoing noncardiac surgery. Ann Intern Med 134:637–643PubMedCrossRef Polanczyk CA, Marcantonio E, Goldman L, Rohde LE, Orav J, Mangione CM, Lee TH (2001) Impact of age on perioperative complications and length of stay in patients undergoing noncardiac surgery. Ann Intern Med 134:637–643PubMedCrossRef
24.
go back to reference Richardson WS, Fuhrman GS, Burch E, Bolton JS, Bowen JC (2001) Outpatient laparoscopic cholecystectomy. Outcomes of 847 planned procedures. Surg Endosc 15:193–195PubMedCrossRef Richardson WS, Fuhrman GS, Burch E, Bolton JS, Bowen JC (2001) Outpatient laparoscopic cholecystectomy. Outcomes of 847 planned procedures. Surg Endosc 15:193–195PubMedCrossRef
25.
go back to reference Uchiyama K, Takifuji K, Tani M, Onishi H, Yamaue H (2002) Effectiveness of the clinical pathway to decrease length of stay and cost for laparoscopic surgery. Surg Endosc 16:1594–1597PubMedCrossRef Uchiyama K, Takifuji K, Tani M, Onishi H, Yamaue H (2002) Effectiveness of the clinical pathway to decrease length of stay and cost for laparoscopic surgery. Surg Endosc 16:1594–1597PubMedCrossRef
26.
go back to reference McAleese P, Odling-Smee W (1994) The effect of complications on length of stay. Ann Surg 220:740–744PubMedCrossRef McAleese P, Odling-Smee W (1994) The effect of complications on length of stay. Ann Surg 220:740–744PubMedCrossRef
27.
go back to reference Kazantsev GB, Schwesinger WH (2002) Shortening postoperative stays. Surg Endosc 16:375–376CrossRef Kazantsev GB, Schwesinger WH (2002) Shortening postoperative stays. Surg Endosc 16:375–376CrossRef
28.
go back to reference Giger UF, Michel JM, Opitz I, Th Inderbitzin D, Kocher T, Krahenbuhl L (2006) Risk factors for perioperative complications in patients undergoing laparoscopic cholecystectomy: analysis of 22,953 consecutive cases from the Swiss Association of Laparoscopic and Thoracoscopic Surgery database. J Am Coll Surg 203:723–728PubMedCrossRef Giger UF, Michel JM, Opitz I, Th Inderbitzin D, Kocher T, Krahenbuhl L (2006) Risk factors for perioperative complications in patients undergoing laparoscopic cholecystectomy: analysis of 22,953 consecutive cases from the Swiss Association of Laparoscopic and Thoracoscopic Surgery database. J Am Coll Surg 203:723–728PubMedCrossRef
29.
go back to reference Kwon AH, Matsui Y (2006) Laparoscopic cholecystectomy in patients aged 80 years and over. World J Surg 30:1204–1210PubMedCrossRef Kwon AH, Matsui Y (2006) Laparoscopic cholecystectomy in patients aged 80 years and over. World J Surg 30:1204–1210PubMedCrossRef
30.
go back to reference McMahon AJ, Fischbacher CM, Frame SH, MacLeod MC (2000) Impact of laparoscopic cholecystectomy: A population-based study. Lancet 356:1632–1637PubMedCrossRef McMahon AJ, Fischbacher CM, Frame SH, MacLeod MC (2000) Impact of laparoscopic cholecystectomy: A population-based study. Lancet 356:1632–1637PubMedCrossRef
31.
go back to reference De Groot V, Beckerman H, Lankhorst GJ, Bouter LM (2003) How to measure comorbidity. A critical review of available methods. J Clin Epidemiol 56:221–229PubMedCrossRef De Groot V, Beckerman H, Lankhorst GJ, Bouter LM (2003) How to measure comorbidity. A critical review of available methods. J Clin Epidemiol 56:221–229PubMedCrossRef
33.
go back to reference Prytherch DR, Whiteley MS, Higgins B, Weaver PC, Prout WG, Powell SJ (1998) POSSUM and Portsmouth POSSUM for predicting mortality. Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity. Br J Surg 85:1217–1220PubMedCrossRef Prytherch DR, Whiteley MS, Higgins B, Weaver PC, Prout WG, Powell SJ (1998) POSSUM and Portsmouth POSSUM for predicting mortality. Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity. Br J Surg 85:1217–1220PubMedCrossRef
34.
go back to reference McAlister FA, Bertsch K, Man J, Bradley J, Jacka M (2005) Incidence of and risk factors for pulmonary complications after nonthoracic surgery. Am J Respir Crit Care Med 171:514–517PubMedCrossRef McAlister FA, Bertsch K, Man J, Bradley J, Jacka M (2005) Incidence of and risk factors for pulmonary complications after nonthoracic surgery. Am J Respir Crit Care Med 171:514–517PubMedCrossRef
35.
go back to reference Lawrence VA, Hilsenbeck SG, Mulrow CD, Dhanda R, Sapp J, Page CP (1995) Incidence and hospital stay for cardiac and pulmonary complications after abdominal surgery. J Gen Intern Med 10:671–678PubMedCrossRef Lawrence VA, Hilsenbeck SG, Mulrow CD, Dhanda R, Sapp J, Page CP (1995) Incidence and hospital stay for cardiac and pulmonary complications after abdominal surgery. J Gen Intern Med 10:671–678PubMedCrossRef
36.
go back to reference Smetana GW, Lawrence VA, Cornell JE (2006) Preoperative pulmonary risk stratification for noncardiothoracic surgery: systematic review for the American College of Physicians. Ann Intern Med 144:581–595PubMedCrossRef Smetana GW, Lawrence VA, Cornell JE (2006) Preoperative pulmonary risk stratification for noncardiothoracic surgery: systematic review for the American College of Physicians. Ann Intern Med 144:581–595PubMedCrossRef
37.
go back to reference Lawrence VA, Cornell JE, Smetana GW (2006) Strategies to reduce postoperative pulmonary complications after noncardiothoracic surgery: systematic review for the American College of Physicians. Ann Intern Med 144:596–608PubMedCrossRef Lawrence VA, Cornell JE, Smetana GW (2006) Strategies to reduce postoperative pulmonary complications after noncardiothoracic surgery: systematic review for the American College of Physicians. Ann Intern Med 144:596–608PubMedCrossRef
38.
go back to reference Nilsson E, Ros A, Rahmqvist M, Backman K, Carlsson P (2004) Cholecystectomy: costs and health-related quality of life: a comparison of two techniques. Int J Qual Health Care 16:473–482PubMedCrossRef Nilsson E, Ros A, Rahmqvist M, Backman K, Carlsson P (2004) Cholecystectomy: costs and health-related quality of life: a comparison of two techniques. Int J Qual Health Care 16:473–482PubMedCrossRef
Metadata
Title
Factors associated with prolonged stay after laparoscopic cholecystectomy in elderly patients
Authors
Shih-Ping Cheng
Yuan-Ching Chang
Chien-Liang Liu
Tsen-Long Yang
Kuo-Shyang Jeng
Jie-Jen Lee
Tsang-Pai Liu
Publication date
01-05-2008
Publisher
Springer-Verlag
Published in
Surgical Endoscopy / Issue 5/2008
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-007-9610-4

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