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Published in:

01-11-2007

Nissen versus Toupet fundoplication: Results of a randomized and multicenter trial

Authors: E. Guérin, K. Bétroune, J. Closset, A. Mehdi, J. C. Lefèbvre, J. J. Houben, M. Gelin, P. Vaneukem, I. El Nakadi

Published in: Surgical Endoscopy | Issue 11/2007

Abstract

Background

Laparoscopic Toupet fundoplication (TF) is reported to be as effective as Nissen (NF), but to be associated with fewer unfavorable postoperative side-effects. This study evaluates the one- and three-year clinical outcome of 140 randomized patients after a laparoscopic NF or TF.

Patients and methods

Inclusion criteria included patients over 16 years old with complications of gastro-oesophageal reflux disease (GORD) and persistence or recurrence of symptoms after three months of treatment. Subjects with a previous history of gastric surgery or repeated fundoplication, brachy-oesophagus or severe abnormal manometry results were excluded. Seventy-seven NF and 63 TF were performed. The severity of symptoms was assessed before and after the procedure.

Results

One hundred and twenty-one of the 140 patients after one year, and 118 after three years, were evaluated and no statistically significant clinical difference was observed. The level of satisfaction concerning the outcome of the operation remained high after one or three years regardless of the type of fundoplication performed.

Conclusions

Functional complications after NF are not avoided with TF.

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Title: Nissen versus Toupet fundoplication: Results of a randomized and multicenter trial
Authors: E. Guérin
K. Bétroune
J. Closset
A. Mehdi
J. C. Lefèbvre
J. J. Houben
M. Gelin
P. Vaneukem
I. El Nakadi
Publication date: 01-11-2007
Publisher: Springer-Verlag
Published in: Surgical Endoscopy / Issue 11/2007
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-007-9474-7

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Nissen versus Toupet fundoplication: Results of a randomized and multicenter trial

Abstract

Background

Patients and methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Patients and methods

Results

Conclusions

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