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Published in: Surgical Endoscopy 7/2007

01-07-2007

The cost of laparoscopic myotomy versus pneumatic dilatation for esophageal achalasia

Authors: Paul J. Karanicolas, Shona E. Smith, Richard I. Inculet, Richard A. Malthaner, Richard P. Reynolds, Ron Goeree, Amiram Gafni

Published in: Surgical Endoscopy | Issue 7/2007

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Abstract

Background

The two main treatment options for esophageal achalasia are laparoscopic distal esophageal myotomy (LM) and pneumatic dilatation (PD). Our objective was to compare the costs of these management strategies.

Methods

We constructed a decision analytic model consisting of two treatment strategies for patients diagnosed with achalasia. Probabilities of events were systematically derived from a literature review, supplemented by expert opinion when necessary. Costs were estimated from the perspective of a third-party payer and society, including both direct and indirect costs. Future costs were discounted at a rate of 5.5% over a time horizon of 5 and 10 years. Uncertainty in the probability estimates was incorporated using probabilistic sensitivity analyses. We tested uncertainty in the model by modifying key assumptions and repeating the analysis.

Results

From the societal perspective, the expected cost per patient was $10,789 (LM) compared with $5,315 (PD) five years following diagnosis, and $11,804 (LM) compared with $7,717 (PD) after 10 years. The 95% confidence interval of the incremental cost per patient treated with LM was ($5,280, $5,668) after five years, and ($3,863, $4,311) after 10 years. The incremental cost of LM was similar from the third-party payer perspective and in the secondary model analyzed.

Conclusions

Initial LM is a more costly management strategy under all clinically plausible scenarios tested in this model. Further research is needed to determine patients’ preferences for the two treatment modalities, and society’s willingness to bear the incremental cost of LM for those who choose it.
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Metadata
Title
The cost of laparoscopic myotomy versus pneumatic dilatation for esophageal achalasia
Authors
Paul J. Karanicolas
Shona E. Smith
Richard I. Inculet
Richard A. Malthaner
Richard P. Reynolds
Ron Goeree
Amiram Gafni
Publication date
01-07-2007
Publisher
Springer-Verlag
Published in
Surgical Endoscopy / Issue 7/2007
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-007-9364-z

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