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Surgical Endoscopy

Published in:

01-04-2007

Endoscopic endoluminal radiofrequency ablation of Barrett’s esophagus in patients with fundoplications

Authors: N. Hubbard, V. Velanovich

Published in: Surgical Endoscopy | Issue 4/2007

Abstract

Background

Endoscopic endoluminal radiofrequency ablation using the Barrx device is a new technique to treat Barrett’s esophagus. This procedure has been used in patients who have not had antireflux surgery. This report is presents an early experience of the effects of endoluminal ablation on the reflux symptoms and completeness of ablation in post-fundoplication patients.

Methods

Seven patients who have had either a laparoscopic or open Nissen fundoplication and Barrett’s esophagus underwent endoscopic endoluminal ablation of the Barrett’s metaplasia using the Barrx device (Barrx Medical, Sunnyvale, CA). Preprocedure, none of the patients had significant symptoms related to gastroesophageal reflux disease. One to two weeks after the ablation, patients were questioned as to the presence of symptoms. Preprocedure and postprocedure, they completed the GERD-HRQL symptom severity questionnaire (best possible score, 0; worst possible score, 50). Patients had follow-up endoscopy to assess completeness of ablation 3 months after the original treatment.

Results

All patients completed the ablation without complications. No patients reported recurrence of their GERD symptoms. The median preprocedure total GERD-HRQL score was 2, compared to a median postprocedure score of 1. One patient had residual Barrett’s metaplasia at 3 months follow-up, requiring re-ablation.

Conclusions

This preliminary report of a small number of patients demonstrates that endoscopic endoluminal ablation of Barrett’s metaplasia using the Barrx device is safe and effective in patients who have already undergone antireflux surgery. There appears to be no disruption in the fundoplication or recurrence of GERD-related symptoms. Nevertheless, longer-term follow-up with more patients is needed.

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Title: Endoscopic endoluminal radiofrequency ablation of Barrett’s esophagus in patients with fundoplications
Authors: N. Hubbard
V. Velanovich
Publication date: 01-04-2007
Publisher: Springer-Verlag
Published in: Surgical Endoscopy / Issue 4/2007
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-007-9199-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Endoscopic endoluminal radiofrequency ablation of Barrett’s esophagus in patients with fundoplications

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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