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Surgical Endoscopy
Published in: Surgical Endoscopy 6/2005

01-06-2005 | Original article

A comparative study of adhesion formation and abdominal wall ingrowth after laparoscopic ventral hernia repair in a porcine model using multiple types of mesh

Authors: J. J. McGinty, N. J. Hogle, H. McCarthy, D. L. Fowler

Published in: Surgical Endoscopy | Issue 6/2005

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Abstract

Background

The ideal mesh for laparoscopic ventral hernia repair is not yet identified.

Methods

We laparoscopically placed polypropylene (PPM), expanded polytetrafluoroethylene (ePTFE), and polyester with antiadhesive collagen layer (PCO) in eight pigs using sutures and tacks for fixation. After 28-day survival, we compared adhesion formation, fibrous ingrowth, and shrinkage among the types of mesh.

Results

Mean area of adhesions to PCO (8.25%) was less than that to ePTFE (57.14%, p < 0.001) or PPM (79.38%, p < 0.001). Adhesions peel strength was less for PCO (2.3 N) than for PPM (16.1 N, p < 0.001) or ePTFE (8.8 N, p = 0.02). Peel strength of mesh from the abdominal wall was less for ePTFE (1.3 N/cm of mesh width) than for PCO (2.8 N/cm, p = 0.001) or PPM (2.1 N/cm, p = 0.05). ePTFE area (94.4 cm2) was less than that for PCO (118.6 cm2, p < 0.001) or PPM (140.7 cm2, p < 0.02).

Conclusion

PCO had fewer and less severe adhesions than ePTFE or PPM while facilitating excellent ingrowth of the adjacent parietal tissue.
Literature
1.
Amid, PK, Shulman, AG, Lichtenstein, IL,  et al. 1994Experimental evaluation of a new composite mesh with the selective property of incorporation to the abdominal wall without adhering to the intestinesJ Biomed Mater Res28373375CrossRefPubMed
2.
Bellon, JM, Contreras, LA, Bujan, J,  et al. 1999Effects of relaparotomy through previously integrated polypropylene and polytetrafluoroethylene experimental implants in the abdominal wallJ Am Coll Surg188466472CrossRefPubMed
3.
Borrazzo EC, Belmont MF, Doffa D, Fowler DF (2004) Effect of prosthetic material on adhesion formation after laparoscopic ventral hernia repair in a porcine model. Surg Endosc 18: 108–112
4.
Ellis, H, Moran, BJ, Thompson, JN,  et al. 1999Adhesion related hospital readmissions after abdominal and pelvic surgery: a retrospective cohort studyLancet35314761480CrossRefPubMed
5.
Heniford, BT, Park, A, Ramshaw, BJ, Voeller, G 2003Laparoscopic repair of ventral hernias: nine years’ experience with 850 consecutive herniasAnn Surg238391400PubMed
6.
Kaufman, Z, Engelberg, M, Zager, M 1981Fecal fistula: a late complication of Marlex mesh repairDis Col Rectum245354
7.
Leber, GE, Garb, JL, Alexander, AL,  et al. 1998Long term complications associated with prosthetic repair of incisional herniasArch Surg133378382CrossRefPubMed
8.
Luijendijk, RW, Lange, DC, Wauters, CC,  et al. 1996Foreign material in postoperative adhesionsAnn Surg223242248CrossRefPubMed
9.
Luijendijk RW, Hop WC, vand den Tol MP, et al (2000) A comparison of suture repair with mesh repair for incisional hernia. N Engl J Med 343: 392–398CrossRefPubMed
10.
Marchal, F, Brunaud, L, Sebbag, H,  et al. 1999Treatment of incisional hernias by placement of an intraperitoneal prosthesis: a series of 128 patientsHernia3141147CrossRef
11.
Matthews, BD, Pratt, BL, Pollnger, HS,  et al. 2003Assessment of adhesion formation to intra-abdominal polypropylene mesh and polytetrafluoroethylene meshJ Surg Res114126132CrossRefPubMed
12.
Mutter, D, Jamali, FR, Moody, GT,  et al. 2000The concept of protected mesh to minimize adhesion foraiation in inteaperitoneal abdominal wall reinforcement. Preclinical evaluation of a new composite meshHernia4S3S9CrossRef
13.
Park, AE, Birch, DW, Lorics, P 1998Laparoscopic and open incisional hernia repair: a comparison studySurgery124816822CrossRefPubMed
14.
Rives, J, Pire, JC, Flament, JB,  et al. 1985Treatment of large eventrations. New therapeutic indications apropos of 322 casesChirurgie111215225PubMed
15.
16.
Therin, M, Mutter, D, Diemunsch, P, Rodeheaver, GT 1998Preclinical evaluation of a new composite mesh (collagen-polyester) for intraperitoneal hernia repair with the selective property of tissue incorporation on one side without adhesion formation on the opposite sideHernia2S27
17.
Voeller, GR, Ramshaw, B, Park, AE, Heniford, BT 1999Incisional hemiaJ Am Coll Surg189635637CrossRefPubMed
18.
Wantz, GE 1991Incisional hernioplasty with MersileneSurg Gynecol Obrstet172129137
Metadata
Title
A comparative study of adhesion formation and abdominal wall ingrowth after laparoscopic ventral hernia repair in a porcine model using multiple types of mesh
Authors
J. J. McGinty
N. J. Hogle
H. McCarthy
D. L. Fowler
Publication date
01-06-2005
Publisher
Springer-Verlag
Published in
Surgical Endoscopy / Issue 6/2005
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-004-8174-9

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