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21-11-2022 | Dysphagia | Original Article

Effect of Modified Pharyngeal Electrical Stimulation on Patients with Severe Chronic Neurogenic Dysphagia: A Single-Arm Prospective Study

Authors: Xue Zhang, Yunxiao Liang, Xiaolu Wang, Yilong Shan, Mengshu Xie, Chao Li, Jiena Hong, Jiemei Chen, Guifang Wan, Yaowen Zhang, Yiqiu Lin, Fei Zhao, Zitong He, Zulin Dou, Hongmei Wen

Published in: Dysphagia | Issue 4/2023

Abstract

Current treatments for severe chronic neurogenic dysphagia (SCND) are limited. Modified pharyngeal electrical stimulation (mPES) was modified from pharyngeal electrical stimulation (PES). This prospective study aimed to explore the efficacy and safety of mPES on SCND. 30 patients with severe chronic neurogenic dysphagia were recruited. mPES was administered to patients once daily until the functional oral intake scale score (FOIS) reach 3. Videofluoroscopic swallow study (VFSS), flexible endoscopic evaluation of swallowing (FEES), and high-resolution manometry (HRM) were utilized for evaluating the swallowing function. After mPES, 24 of 30 patients (80%) reached the endpoint (FOIS = 3) (P < 0.001). 3 of 6 tracheotomized patients (50%) removed the tracheal tube. The median number of mPES sessions for the 24 patients who met the criteria was 28 (17, 38) and the median period was 43 (29, 63) days. Moreover, a significant increase was observed in hypopharyngeal peak pressure (P = 0.015), hypopharyngeal contraction duration (P = 0.023), velopharyngeal peak pressure (P = 0.044), and velopharyngeal contraction duration (P = 0.031). A reduction was observed in PAS (P < 0.001), secretion (P = 0.001), vallecular residue (P < 0.001), left (P = 0.001), and right (P < 0.001) pyriform sinus residue. The median FOIS of 30 patients at 3-month follow-up was 5 (3, 6). No serious side effects were reported. mPES is a promising effective and safe therapeutic approach that is simple to use in patients with SCND.

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Title: Effect of Modified Pharyngeal Electrical Stimulation on Patients with Severe Chronic Neurogenic Dysphagia: A Single-Arm Prospective Study
Authors: Xue Zhang
Yunxiao Liang
Xiaolu Wang
Yilong Shan
Mengshu Xie
Chao Li
Jiena Hong
Jiemei Chen
Guifang Wan
Yaowen Zhang
Yiqiu Lin
Fei Zhao
Zitong He
Zulin Dou
Hongmei Wen
Publication date: 21-11-2022
Publisher: Springer US
Keywords: Dysphagia
Dysphagia
Dysphagia
Flexible Endoscopic Evaluation of Swallowing
Flexible Endoscopic Evaluation of Swallowing
Published in: Dysphagia / Issue 4/2023
Print ISSN: 0179-051X
Electronic ISSN: 1432-0460
DOI: https://doi.org/10.1007/s00455-022-10536-z

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Effect of Modified Pharyngeal Electrical Stimulation on Patients with Severe Chronic Neurogenic Dysphagia: A Single-Arm Prospective Study

Abstract

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Abstract

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