Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Dysphagia
Published in: Dysphagia 6/2020

01-12-2020 | Dysphagia | Original Article

Prognostic Prediction of Dysphagia by Analyzing the Corticobulbar Tract in the Early Stage of Intracerebral Hemorrhage

Published in: Dysphagia | Issue 6/2020

Login to get access

Abstract

We investigated the predictive value of the corticobulbar tract (CBT) for dysphagia using diffusion tensor tractography in the early stage of intracerebral hemorrhage (ICH) for dysphagia. Forty-two patients with spontaneous ICH ± intraventricular hemorrhage (IVH) and 22 control subjects were recruited. The patients were classified into three groups: group A—could remove nasogastric tube (NGT) in the acute stage of ICH, group B—could remove NGT within 6 months after onset, and group C—could not remove NGT until 6 months after onset. The CBT were reconstructed, and fractional anisotropy (FA) and tract volume (TV) values were determined. The FA of the CBT in the affected hemisphere in group A was lower than in the control group (p < 0.05). The FA and TV of the CBT in the affected hemisphere in group B were lower than those in the control group (p < 0.05). In group C, the FA and TV in the affected hemisphere and unaffected hemispheres were lower than in the control group (p < 0.05). The TV of the CBT in the affected hemisphere in group B showed a moderate negative correlation with the length of time until NGT removal (r = 0.430, p < 0.05). We found that patients with CBT injuries in both hemispheres were not able to remove the NGT until 6 months after onset, whereas patients who were injured only in the affected hemisphere were able to remove NGT within 6 months of onset. The severity of injury to the CBT in the affected hemisphere appeared to be related to the length of time until NGT removal.
Literature
1.
Martino R, Foley N, Bhogal S, Diamant N, Speechley M, Teasell R. Dysphagia after stroke: Incidence, diagnosis, and pulmonary complications. Stroke. 2005;36:2756–63.PubMed
2.
O’Neill PA, Smithard DG, Morris J. Complications and outcome following acute stroke: revised table. Stroke. 1998;29:1480–1.PubMed
3.
Mann G, Hankey GJ, Cameron D. Swallowing disorders following acute stroke: prevalence and diagnostic accuracy. Cerebrovasc Dis. 2000;10:380–6.PubMed
4.
Guyomard V, Fulcher RA, Redmayne O, Metcalf AK, Potter JF, Myint PK. Effect of dysphasia and dysphagia on inpatient mortality and hospital length of stay: a database study. J Am Geriatr Soc. 2009;57:2101–6.PubMed
5.
Wilson RD. Mortality and cost of pneumonia after stroke for different risk groups. J Stroke Cerebrovasc Dis. 2012;10:61–7.
6.
Lin WC, Huang CY, Lee LF, Chen YW, Ho CH, Sun YT. Initial National Institute of Health Stroke Scale to early predict the improvement of swallowing in patients with acute ischemic stroke. J Stroke Cerebrovasc Dis. 2019;28:104297.PubMed
7.
Schmidt J, Holas M, Halvorson K, Reding M. Videofluoroscopic evidence of aspiration predicts pneumonia and death but not dehydration following stroke. Dysphagia. 1994;9:7–11.PubMed
8.
Kalra L, Smith DH, Crome P. Stroke in patients aged over 75 years: outcome and predictors. Postgrad Med J. 1993;69:33–6.PubMedPubMedCentral
9.
Eslick GD, Talley NJ. Dysphagia: epidemiology, risk factors and impact on quality of life—a population-based study. Aliment Pharmacol Ther. 2008;27:971–9.PubMed
10.
Ickenstein GW, Stein J, Ambrosi D, Goldstein R, Horn M, Bogdahn U. Predictors of survival after severe dysphagic stroke. J Neurol. 2005;252:1510–6.PubMed
11.
Ickenstein GW, Kelly PJ, Furie KL, Ambrosi D, Rallis N, Goldstein R, et al. Predictors of feeding gastrostomy tube removal in stroke patients with dysphagia. J Stroke Cerebrovasc Dis. 2003;12:169–74.PubMed
12.
Broadley S, Croser D, Cottrell J, Creevy M, Teo E, Yiu D, et al. Predictors of prolonged dysphagia following acute stroke. J Clin Neurosci. 2003;10:300–5.PubMed
13.
Kumar S, Doughty C, Doros G, Selim M, Lahoti S, Gokhale S, Schlaug G. Recovery of swallowing after dysphagic stroke: an analysis of prognostic factors. J Stroke Cerebrovasc Dis. 2014;23:56–62.PubMed
14.
Maeshima S, Okazaki H, Okamoto S, Mizuno S, Asano N, Tsunoda T, et al. Dysphagia following putaminal hemorrhage at a rehabilitation hospital. J Stroke Cerebrovasc Dis. 2016;25:389–96.PubMed
15.
Maeshima S, Osawa A, Yamane F, Ishihara S, Tanahashi N. Dysphagia following acute thalamic haemorrhage: clinical correlates and outcomes. Eur Neurol. 2014;71:165–72.PubMed
16.
Flowers HL, AlHarbi MA, Mikulis D, Silver FL, Rochon E, Streiner D, Martino R. MRI-based neuroanatomical predictors of dysphagia, dysarthria, and aphasia in patients with first acute ischemic stroke. Cerebrovasc Dis Extra. 2017;7:21–34.PubMedPubMedCentral
17.
Mann G, Hankey GJ, Cameron D. Swallowing function after stroke: prognosis and prognostic factors at 6 months. Stroke. 1999;30:744–8.PubMed
18.
Ween JE, Alexander MP, D’Esposito M, Roberts M. Incontinence after stroke in a rehabilitation setting: outcome associations and predictive factors. Neurology. 1996;47:659–63.PubMed
19.
Daniels SK, McAdam CP, Brailey K, Foundas AL. Clinical assessment of swallowing and prediction of dysphagia severity. Am J Speech Lang Pathol. 1997;6:17–24.
20.
Horner J, Massey EW, Riski JE, Lathrop DL, Chase KN. Aspiration following stroke: clinical correlates and outcome. Neurology. 1988;38:1359–62.PubMed
21.
Broadley S, Croser D, Cottrell J, Creevy M, Teo E, Yiu D, Pathi R, Taylor J, Thompson PD. Predictors of prolonged dysphagia following acute stroke. J Clin Neurosci. 2003;10:300–5.PubMed
22.
Okubo PC, Fabio SR, Domenis DR, Takayanagui OM. Using the national institute of health stroke scale to predict dysphagia in acute ischemic stroke. Cerebrovasc Dis. 2012;33:501–7.PubMed
23.
Joundi RA, Martino R, Saposnik G, Giannakeas V, Fang J, Kapral MK. Predictors and outcomes of dysphagia screening after acute ischemic stroke. Stroke. 2017;48:900–6.PubMed
24.
Kwon HG, Lee J, Jang SH. Injury of the corticobulbar tract in patients with dysarthria following cerebral infarct: diffusion tensor tractography study. Int J Neurosci. 2016;126:361–5.PubMed
25.
Jenabi M, Peck KK, Young RJ, Brennan N, Holodny AI. Identification of the corticobulbar tracts of the tongue and face using deterministic and probabilistic DTI fiber tracking in patients with brain tumor. Am J Neuroradiol. 2015;36:2036–41.PubMedPubMedCentral
26.
Jang SH, Seo JP. The anatomical location of the corticobulbar tract at the corona radiata in the human brain: diffusion tensor tractography study. Neurosci Lett. 2015;590:80–3.PubMed
27.
Jang SH, Kim SH, Kwon YH. Extensive traumatic axonal injury of brain due to violence: a case report. Medicine (Baltim). 2018;97:e13315.
28.
Jang SH, Lee HD. Weak phonation due to unknown injury of the corticobulbar tract in a patient with mild traumatic brain injury: a diffusion tensor tractography study. Neural Regen Res. 2018;13:936.PubMedPubMedCentral
29.
Jang SH, Seo YS. Dysarthria due to injury of the corticobulbar tract in a patient with mild traumatic brain injury. Am J Phys Med Rehabil. 2016;95:e187–8.PubMed
30.
Pan C, Peck KK, Young RJ, Holodny AI. Somatotopic organization of motor pathways in the internal capsule: a probabilistic diffusion tractography study. Am J Neuroradiol. 2012;33:1274–80.PubMedPubMedCentral
31.
Yim SH, Kim JH, Han ZA, Jeon S, Cho JH, Kim GS, Choi SA, Lee JH. Distribution of the corticobulbar tract in the internal capsule. J Neurol Sci. 2013;334:63–8.PubMed
32.
Jang SH, Lee J, Kwon HG. Reorganization of the corticobulbar tract in a patient with bilateral middle cerebral artery territory infarct. Am J Phys Med Rehabil. 2016;95:e58–9.PubMed
33.
Kim HK, Han M, Lee HJ. Corticobulbar tract involvement in neuropsychiatric systemic lupus erythematosus: a case report. Iran J Radiol. 2016;13:e32927.PubMedPubMedCentral
34.
35.
Jang SH, Kim SH, Seo JP. Image of the month: dysphasia due to injury of the corticobulbar tract following traumatic brain injury. Clin Med (Lond). 2017;17:584–5.
36.
Moon HI, Kim GS, Lee E. Is the location of white matter lesions important in the swallowing function of older patients with mild stroke? Dysphagia. 2018;34(3):407–14.PubMed
37.
Trapl M, Enderle P, Nowotny M, Teuschl Y, Matz K, Dachenhausen A, Brainin M. Dysphagia bedside screening for acute-stroke patients: the Gugging Swallowing Screen. Stroke. 2007;38:2948–52.PubMed
38.
Rosenbek JC, Robbins JA, Roecker EB, Coyle JL, Wood JL. A penetration-aspiration scale. Dysphagia. 1996;11:93–8.PubMed
39.
Han TR, Paik NJ, Park JW. Quantifying swallowing function after stroke: a functional dysphagia scale based on videofluoroscopic studies. Arch Phys Med Rehabil. 2001;82:677–82.PubMed
40.
Kothari RU, Brott T, Broderick JP, Barsan WG, Sauerbeck LR, Zuccarello M, Khoury J. The ABCs of measuring intracerebral hemorrhage volumes. Stroke. 1996;27:1304–5.PubMed
41.
Staykov D, Wagner I, Volbers B, Hauer EM, Doerfler A, Schwab S, Bardutzky J. Natural course of perihemorrhagic edema after intracerebral hemorrhage. Stroke. 2011;42:2625–9.PubMed
42.
Lee SH, Park HK, Ryu WS, Lee JS, Bae HJ, Han MK, Lee YS, Kwon HM, Kim CK, Park ES, Chung JW, Jung KH, Roh JK. Effects of celecoxib on hematoma and edema volumes in primary intracerebral hemorrhage: a multicenter randomized controlled trial. Eur J Neurol. 2013;20:1161–9.PubMed
43.
Morgan TC, Dawson J, Spengler D, Lees KR, Aldrich C, Mishra NK, et al. The Modified Graeb Score: an enhanced tool for intraventricular hemorrhage measurement and prediction of functional outcome. Stroke. 2013;44:635–41.PubMedPubMedCentral
44.
Smith SM, Jenkinson M, Woolrich MW, Beckmann CF, Behrens TE, Johansen-Berg H, Bannister PR, De Luca M, Drobnjak I, Flitney DE, Niazy RK, Saunders J, Vickers J, Zhang Y, De Stefano N, Brady JM, Matthews PM. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage. 2004;23(Suppl 1):S208–19.PubMed
45.
Behrens TE, Berg HJ, Jbabdi S, Rushworth MF, Woolrich MW. Probabilistic diffusion tractography with multiple fibre orientations: what can we gain? Neuroimage. 2007;34:144–55.PubMed
46.
Behrens TE, Johansen-Berg H, Woolrich M, Smith S, Wheeler-Kingshott C, Boulby P, Barker G, Sillery E, Sheehan K, Ciccarelli O. Non-invasive mapping of connections between human thalamus and cortex using diffusion imaging. Nat Neurosci. 2003;6:750.PubMed
47.
Wuensch KL. Straightforward statistic for the behavioral sciences. J Am Stat Assoc. 1996;91:1750.
48.
Lim KO, Hedehus M, Moseley M, de Crespigny A, Sullivan EV, Pfefferbaum A. Compromised white matter tract integrity in schizophrenia inferred from diffusion tensor imaging. Arch Gen Psychiatry. 1999;56:367–74.PubMed
49.
Filippi M, Cercignani M, Inglese M, Horsfield M, Comi G. Diffusion tensor magnetic resonance imaging in multiple sclerosis. Neurology. 2001;56:304–11.PubMed
50.
Mori S, Frederiksen K, Van Zijl PC, Stieltjes B, Kraut MA, Solaiyappan M, Pomper MG. Brain white matter anatomy of tumor patients evaluated with diffusion tensor imaging. Ann Neurol. 2002;51:377–80.PubMed
51.
52.
Mori S, van Zijl PC. Fiber tracking: principles and strategies—a technical review. NMR Biomed. 2002;15:468–80.PubMed
53.
Seo JP, Jang SH. Different characteristics of the corticospinal tract according to the cerebral origin: DTI study. Am J Neuroradiol. 2013;34:1359–63.PubMedPubMedCentral
54.
Kwon HG, Choi BY, Kim SH, Chang CH, Jung YJ, Lee HD, Jang SH. Injury of the cingulum in patients with putaminal hemorrhage: a diffusion tensor tractography study. Front Hum Neurosci. 2014;8:366.PubMedPubMedCentral
55.
Yeo SS, Choi BY, Chang CH, Jung YJ, Ahn SH, Son SM, Byun WM, Jang SH. Periventricular white matter injury by primary intraventricular hemorrhage: a diffusion tensor imaging study. Eur Neurol. 2011;66:235–41.PubMed
56.
Barritt AW, Smithard DG. Role of cerebral cortex plasticity in the recovery of swallowing function following dysphagic stroke. Dysphagia. 2009;24:83.PubMed
57.
Jang SH, Shin SM. The usefulness of diffusion tensor tractography for estimating the state of corticobulbar tract in stroke patients. Clin Neurophysiol. 2016;127:2708–9.PubMed
58.
Yamada K, Sakai K, Akazawa K, Yuen S, Nishimura T. MR tractography: a review of its clinical applications. Magn Reson Med Sci. 2009;8:165–74.PubMed
Metadata
Title
Prognostic Prediction of Dysphagia by Analyzing the Corticobulbar Tract in the Early Stage of Intracerebral Hemorrhage
Publication date
01-12-2020
Published in
Dysphagia / Issue 6/2020
Print ISSN: 0179-051X
Electronic ISSN: 1432-0460
DOI
https://doi.org/10.1007/s00455-020-10093-3

Other articles of this Issue 6/2020

Dysphagia 6/2020 Go to the issue

Original Article

A Systematic Review of Tracheostomy Modifications and Swallowing in Adults

Original Article

Evaluating the Psychometric Properties of the Kannada Version of EAT 10

Original Article

Swallow Safety in Infant Pigs With and Without Recurrent Laryngeal Nerve Lesion

Original Article

Handheld Cough Testing: A Novel Tool for Cough Assessment and Dysphagia Screening

Original Article

Insulin-Like Growth Factor-1 (IGF-1) and Reduced Tongue Pressure in Relation to Atherosclerosis Among Community-Dwelling Elderly Japanese Men: A Cross-Sectional Study

Review

A Systematic Review of the Influence of Bolus Characteristics on Respiratory Measures in Healthy Swallowing