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Published in: Dysphagia 5/2020

01-10-2020 | Dysphagia | Original Article

Association Between Dysphagia and Inpatient Outcomes Across Frailty Level Among Patients ≥ 50 Years of Age

Authors: Seth M. Cohen, Deborah Lekan, Thomas Risoli Jr., Hui-Jie Lee, Stephanie Misono, Heather E. Whitson, Sudha Raman

Published in: Dysphagia | Issue 5/2020

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Abstract

Frail patients may have heightened risk of dysphagia, a potentially modifiable health factor. Our aim is to examine whether the relationship between dysphagia and adverse health outcomes differs by frailty conditions among inpatients ≥ 50 years of age. Medical or surgical hospitalizations among patients ≥ 50 years of age in the Healthcare Cost and Utilization Project’s National Inpatient Sample from 2014 through the first three quarters of 2015 were included. Adverse outcomes included length of stay (LOS), hospital costs, in-hospital mortality, discharge status, and medical complications. Dysphagia was determined by ICD-9-CM codes. Frailty was defined as (a) ≥ 1 condition in the10-item Johns Hopkins Adjusted Clinical Groups (ACG) frailty measure and a frailty index for the (b) ACG and (c) a 19-item Frailty Risk Score (FRS) categorized as non-frail, pre-frail, and frail. Weighted generalized linear models for complex survey designs using generalized estimating equations were performed. Of 6,230,114 unweighted hospitalizations, 4.0% had a dysphagia diagnosis. Dysphagia presented in 3.1% and 11.0% of non-frail and frail hospitalizations using the binary ACG (p < 0.001) and in 2.9%, 7.9%, and 16.0% of non-frail, pre-frail, and frail hospitalizations using the indexed FRS (p < 0.001). Dysphagia was associated with greater LOS, higher total costs, increased non-routine discharges, and more medical complications among both frail and non-frail patients using the three frailty definitions. Dysphagia was associated with adverse outcomes in both frail and non-frail medical or surgical hospitalizations. Dysphagia management is an important consideration for providers seeking to reduce risk in vulnerable populations.
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Literature
1.
go back to reference Regan J, Lawson S, De Aguiar V. The eating assessment tool-10 predicts aspiration in adults with stable chronic obstructive pulmonary disease. Dysphagia. 2017;32:714–20.PubMed Regan J, Lawson S, De Aguiar V. The eating assessment tool-10 predicts aspiration in adults with stable chronic obstructive pulmonary disease. Dysphagia. 2017;32:714–20.PubMed
2.
go back to reference Roden DF, Altman KW. Causes of dysphagia among different age groups A systematic review of the literature. Otolaryngol Clin North Am. 2013;46(6):965–87.PubMed Roden DF, Altman KW. Causes of dysphagia among different age groups A systematic review of the literature. Otolaryngol Clin North Am. 2013;46(6):965–87.PubMed
3.
go back to reference Bhattacharyya N. The prevalence of dysphagia among adults in the United States. Otolaryngol Head Neck Surg. 2014;151:765–9.PubMed Bhattacharyya N. The prevalence of dysphagia among adults in the United States. Otolaryngol Head Neck Surg. 2014;151:765–9.PubMed
4.
go back to reference Baijens LW, Clave P, Cras P, et al. European Society for Swallowing Disorders - European Union Geriatric Medicine Society white paper: oropharyngeal dysphagia as a geriatric syndrome. Clin Interv Aging. 2016;11:1403–28.PubMedPubMedCentral Baijens LW, Clave P, Cras P, et al. European Society for Swallowing Disorders - European Union Geriatric Medicine Society white paper: oropharyngeal dysphagia as a geriatric syndrome. Clin Interv Aging. 2016;11:1403–28.PubMedPubMedCentral
5.
go back to reference Guyomard V, Fulcher RA, Redmayne O, Metcalf AK, Potter JF, Myint PK. Effect of dysphasia and dysphagia on inpatient mortality and hospital length of stay: a database study. J Am Geriatr Soc. 2009;57(11):2101–6.PubMed Guyomard V, Fulcher RA, Redmayne O, Metcalf AK, Potter JF, Myint PK. Effect of dysphasia and dysphagia on inpatient mortality and hospital length of stay: a database study. J Am Geriatr Soc. 2009;57(11):2101–6.PubMed
6.
go back to reference Altman KW, Yu GP, Schaefer SD. Consequence of dysphagia in the hospitalized patient: impact on prognosis and hospital resources. Arch Otolaryngol Head Neck Surg. 2010;136(8):784–9.PubMed Altman KW, Yu GP, Schaefer SD. Consequence of dysphagia in the hospitalized patient: impact on prognosis and hospital resources. Arch Otolaryngol Head Neck Surg. 2010;136(8):784–9.PubMed
7.
go back to reference van der Maarel-Wierink CD, Vanobbergen JN, Bronkhorst EM, Schols JM, de Baat C. Meta-analysis of dysphagia and aspiration pneumonia in frail elders. J Dent Res. 2011;90(12):1398–404.PubMed van der Maarel-Wierink CD, Vanobbergen JN, Bronkhorst EM, Schols JM, de Baat C. Meta-analysis of dysphagia and aspiration pneumonia in frail elders. J Dent Res. 2011;90(12):1398–404.PubMed
8.
go back to reference Patel DA, Krishnaswami S, Steger E, Conover E, Vaezi MF, Cuicci MR, Francis DO. Economic and survival burden of dysphagia among inpatients in the United States. Dis Esophagus. 2018;31(1):1–7.PubMed Patel DA, Krishnaswami S, Steger E, Conover E, Vaezi MF, Cuicci MR, Francis DO. Economic and survival burden of dysphagia among inpatients in the United States. Dis Esophagus. 2018;31(1):1–7.PubMed
9.
go back to reference Ortega O, Martin A, Clave P. Diagnosis and management of oropharyngeal dysphagia among older persons, state of the art. J Am Med Dir Assoc. 2017;18(7):576–82.PubMed Ortega O, Martin A, Clave P. Diagnosis and management of oropharyngeal dysphagia among older persons, state of the art. J Am Med Dir Assoc. 2017;18(7):576–82.PubMed
10.
go back to reference Clave P, Shaker R. Dysphagia: current reality and scope of the problem. Nat Rev Gastroenterol Hepatol. 2015;12:259–70.PubMed Clave P, Shaker R. Dysphagia: current reality and scope of the problem. Nat Rev Gastroenterol Hepatol. 2015;12:259–70.PubMed
11.
go back to reference Madhavan A, LaGorio LA, Crary MA, Dahl WJ, Carnaby GD. Prevalence of and risk factors for dysphagia in the community dwelling elderly: a systematic review. J Nutr Health Aging. 2016;20(8):806–15.PubMed Madhavan A, LaGorio LA, Crary MA, Dahl WJ, Carnaby GD. Prevalence of and risk factors for dysphagia in the community dwelling elderly: a systematic review. J Nutr Health Aging. 2016;20(8):806–15.PubMed
12.
go back to reference Maeda K, Akagi J. Sarcopenia is an independent risk factor of dysphagia in hospitalized older people. Geriatr Gerontol Int. 2016;16(4):515–21.PubMed Maeda K, Akagi J. Sarcopenia is an independent risk factor of dysphagia in hospitalized older people. Geriatr Gerontol Int. 2016;16(4):515–21.PubMed
13.
go back to reference Maeda K, Takaki M, Akagi J. Decreased skeletal muscle mass and risk factors of sarcopenic dysphagia: a prospective observational cohort study. J Gerontol A Biol Sci Med Sci. 2017;72(9):1290–4.PubMed Maeda K, Takaki M, Akagi J. Decreased skeletal muscle mass and risk factors of sarcopenic dysphagia: a prospective observational cohort study. J Gerontol A Biol Sci Med Sci. 2017;72(9):1290–4.PubMed
14.
go back to reference Yang EJ, Kim MH, Lim JY, Paik NJ. Oropharyngeal Dysphagia in a community-based elderly cohort: the Korean longitudinal study on health and aging. J Korean Med Sci. 2013;28(10):1534–9.PubMedPubMedCentral Yang EJ, Kim MH, Lim JY, Paik NJ. Oropharyngeal Dysphagia in a community-based elderly cohort: the Korean longitudinal study on health and aging. J Korean Med Sci. 2013;28(10):1534–9.PubMedPubMedCentral
15.
go back to reference Sternberg SA, Wershof Schwartz A, Karunananthan S, Bergman H, Mark CA. The identification of frailty: a systematic literature review. J Am Geriatr Soc. 2011;59(11):2129–38.PubMed Sternberg SA, Wershof Schwartz A, Karunananthan S, Bergman H, Mark CA. The identification of frailty: a systematic literature review. J Am Geriatr Soc. 2011;59(11):2129–38.PubMed
16.
go back to reference Starmer HM, Quon H, Simpson M, Webster K, Tippett D, Herbert RJ, Eisele DW, Gourin CG. Speech-language pathology care and short- and long-term outcomes of laryngeal cancer treatment in the elderly. Laryngoscope. 2015;125(12):2756–63.PubMed Starmer HM, Quon H, Simpson M, Webster K, Tippett D, Herbert RJ, Eisele DW, Gourin CG. Speech-language pathology care and short- and long-term outcomes of laryngeal cancer treatment in the elderly. Laryngoscope. 2015;125(12):2756–63.PubMed
17.
go back to reference Alvarez-Hernandez J, PlanasVila M, Leon-Sanz M, de Lorenzo AG, Celaya-Perez S, Garcia-Lorda P, Araujo K, SartoGuerri B, Researchers PR. Prevalence and costs of malnutrition in hospitalized patients: the PREDyCES Study. Nutr Hosp. 2012;27(4):1049–59.PubMed Alvarez-Hernandez J, PlanasVila M, Leon-Sanz M, de Lorenzo AG, Celaya-Perez S, Garcia-Lorda P, Araujo K, SartoGuerri B, Researchers PR. Prevalence and costs of malnutrition in hospitalized patients: the PREDyCES Study. Nutr Hosp. 2012;27(4):1049–59.PubMed
18.
go back to reference Starmer HM, Riley LH 3rd, Hillel AT, Akst LM, Best SR, Gourin CG. Dysphagia, short-term outcomes, and cost of care after anterior cervical disc surgery. Dysphagia. 2014;29(1):68–77.PubMed Starmer HM, Riley LH 3rd, Hillel AT, Akst LM, Best SR, Gourin CG. Dysphagia, short-term outcomes, and cost of care after anterior cervical disc surgery. Dysphagia. 2014;29(1):68–77.PubMed
19.
go back to reference Carrion S, Cabre M, Monteis R, et al. Oropharyngeal dysphagia is a prevalent risk factor for malnutrition in a cohort of older patients admitted with an acute disease to a general hospital. Clin Nutr. 2015;34(3):436–42.PubMed Carrion S, Cabre M, Monteis R, et al. Oropharyngeal dysphagia is a prevalent risk factor for malnutrition in a cohort of older patients admitted with an acute disease to a general hospital. Clin Nutr. 2015;34(3):436–42.PubMed
20.
go back to reference Brodsky R. Nutrition issues in Dysphagia: identification, management, and the role of the dietician. Nutr Clin Pract. 1999;14:S47–S51. Brodsky R. Nutrition issues in Dysphagia: identification, management, and the role of the dietician. Nutr Clin Pract. 1999;14:S47–S51.
21.
go back to reference Langmore SE, Terpenning MS, Schork A, et al. Predictors of aspiration pneumonia: how important is dysphagia? Dysphagia. 1998;13(2):69–81.PubMed Langmore SE, Terpenning MS, Schork A, et al. Predictors of aspiration pneumonia: how important is dysphagia? Dysphagia. 1998;13(2):69–81.PubMed
22.
go back to reference Payne M, Morley JE. Editorial: dysphagia, dementia, and frailty. J Nutr Health Aging. 2018;22(5):562–5.PubMed Payne M, Morley JE. Editorial: dysphagia, dementia, and frailty. J Nutr Health Aging. 2018;22(5):562–5.PubMed
23.
go back to reference Bock JM, Varadarajan V, Brawley MC, Blumin JH. Evaluation of the natural history of patients who aspirate. Laryngoscope. 2017;127(Suppl 8):S1–S10.PubMedPubMedCentral Bock JM, Varadarajan V, Brawley MC, Blumin JH. Evaluation of the natural history of patients who aspirate. Laryngoscope. 2017;127(Suppl 8):S1–S10.PubMedPubMedCentral
24.
go back to reference Santos-Eggimann B, Cuenoud P, Spagnoli J, Junod J. Prevalence of frailty in middle-aged and older community dwelling Europeans living in 10 countries. J Gerontol A Biol Sci Med Sci. 2009;64(6):675–81.PubMed Santos-Eggimann B, Cuenoud P, Spagnoli J, Junod J. Prevalence of frailty in middle-aged and older community dwelling Europeans living in 10 countries. J Gerontol A Biol Sci Med Sci. 2009;64(6):675–81.PubMed
25.
go back to reference Hanlon P, Nicholl BI, Jani BD, Lee D, McQueenie R, Mair FS. Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: a prospective anlaysis of 493.737 UK Biobank participants. Lancet Public Health. 2018;3(7):e323–e332332.PubMedPubMedCentral Hanlon P, Nicholl BI, Jani BD, Lee D, McQueenie R, Mair FS. Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: a prospective anlaysis of 493.737 UK Biobank participants. Lancet Public Health. 2018;3(7):e323–e332332.PubMedPubMedCentral
28.
go back to reference Nieman CL, Pitman KT, Tufaro AP, Eisele DW, Frick KD, Gourin CG. The effect of frailty on short-term outcomes after head and neck cancer surgery. Laryngoscope. 2018;128(1):102–10.PubMed Nieman CL, Pitman KT, Tufaro AP, Eisele DW, Frick KD, Gourin CG. The effect of frailty on short-term outcomes after head and neck cancer surgery. Laryngoscope. 2018;128(1):102–10.PubMed
29.
go back to reference González-Fernández M, Gardyn M, Wyckoff S, Ky PK, Palmer JB. Validation of ICD-9 Code 787.2 for identification of individuals with dysphagia from administrative databases. Dysphagia 2009;24:398–402.PubMed González-Fernández M, Gardyn M, Wyckoff S, Ky PK, Palmer JB. Validation of ICD-9 Code 787.2 for identification of individuals with dysphagia from administrative databases. Dysphagia 2009;24:398–402.PubMed
30.
go back to reference The Johns Hopkins ACG System: Version 11.0 Technical Reference Guide. Chapter 2. Baltimore, MD: The Johns Hopkins University; 2015. The Johns Hopkins ACG System: Version 11.0 Technical Reference Guide. Chapter 2. Baltimore, MD: The Johns Hopkins University; 2015.
31.
go back to reference McIsaac DI, Bryson GL, Van Walraven C. Association of 1-year postoperative mortality following major elective noncardiace surgery: a population-based cohort study. JAMA Surg. 2016;151(6):538–45.PubMed McIsaac DI, Bryson GL, Van Walraven C. Association of 1-year postoperative mortality following major elective noncardiace surgery: a population-based cohort study. JAMA Surg. 2016;151(6):538–45.PubMed
32.
go back to reference McIsaac DI, Beaule PE, Bryson GL, Van Walraven C. The impact of frailty on outcomes and healthcare resource usage after total joint arthroplasty: a population-based cohort study. Bone Joint J. 2016;98B(6):799–805. McIsaac DI, Beaule PE, Bryson GL, Van Walraven C. The impact of frailty on outcomes and healthcare resource usage after total joint arthroplasty: a population-based cohort study. Bone Joint J. 2016;98B(6):799–805.
33.
go back to reference Sternberg S, Bentur N, Abrams C, et al. Identifying frail old people using predictive modeling. Am J Manag Care 2012;18(10):e392–7.PubMed Sternberg S, Bentur N, Abrams C, et al. Identifying frail old people using predictive modeling. Am J Manag Care 2012;18(10):e392–7.PubMed
34.
go back to reference Lekan DA, Wallace DC, McCoy TP, Hu J, Silva SG, Whitson HE. Frailty assessment in hospitalized older adults using electronic health record. Biol Res Nurs. 2017;19(2):213–28.PubMed Lekan DA, Wallace DC, McCoy TP, Hu J, Silva SG, Whitson HE. Frailty assessment in hospitalized older adults using electronic health record. Biol Res Nurs. 2017;19(2):213–28.PubMed
35.
go back to reference Lekan DA, McCoty TP. Frailty risk in hospitalized older adults with and without diabetes mellitus. J Clin Nurs. 2018;27(19–20):3510–21.PubMed Lekan DA, McCoty TP. Frailty risk in hospitalized older adults with and without diabetes mellitus. J Clin Nurs. 2018;27(19–20):3510–21.PubMed
36.
go back to reference Elixhauser A, Steiner C, Harris DR, Coffey RM. Comorbidity measures for use with administrative data. Med Care. 1998;36(1):8–27.PubMed Elixhauser A, Steiner C, Harris DR, Coffey RM. Comorbidity measures for use with administrative data. Med Care. 1998;36(1):8–27.PubMed
39.
go back to reference Hardin JW, Hilbe JM. Generalized linear models and extensions. 2nd ed. College Station, TX: Stata Press; 2007. p. 89. Hardin JW, Hilbe JM. Generalized linear models and extensions. 2nd ed. College Station, TX: Stata Press; 2007. p. 89.
41.
go back to reference Rao JNK, Scott AJ. On simple adjustments to chi-square tests with survey data. Ann Stat. 1987;15:385–97. Rao JNK, Scott AJ. On simple adjustments to chi-square tests with survey data. Ann Stat. 1987;15:385–97.
42.
go back to reference Rockwood K, Andrew M, Mitnitski A. A comparison of two approaches to measuring frailty in elderly people. J Gerontol A Biol Sci Med Sci. 2007;62(7):738–43.PubMed Rockwood K, Andrew M, Mitnitski A. A comparison of two approaches to measuring frailty in elderly people. J Gerontol A Biol Sci Med Sci. 2007;62(7):738–43.PubMed
43.
go back to reference Rockwood K, Howlett SE, MacKnight C, et al. Prevalence, attributes, and outcomes of fitness and frailty in community-dwelling older adults: report from the Canadian Study of Health and Aging. J Gerontol A Biol Sci Med Sci. 2004;59(12):1310–7.PubMed Rockwood K, Howlett SE, MacKnight C, et al. Prevalence, attributes, and outcomes of fitness and frailty in community-dwelling older adults: report from the Canadian Study of Health and Aging. J Gerontol A Biol Sci Med Sci. 2004;59(12):1310–7.PubMed
44.
go back to reference Song X, Mitnitski A, Rockwood K. Prevalence and 10-year outcomes of frailty in older adults in relation to deficit accumulation. J Am Geritr Soc. 2010;58(4):681–7. Song X, Mitnitski A, Rockwood K. Prevalence and 10-year outcomes of frailty in older adults in relation to deficit accumulation. J Am Geritr Soc. 2010;58(4):681–7.
45.
go back to reference Searle SD, Mitnitski A, Gahbauer EA, Gill TM, Rockwood K. A standard procedure for creating a frailty index. BMC Geriatr 2018;8:24. Searle SD, Mitnitski A, Gahbauer EA, Gill TM, Rockwood K. A standard procedure for creating a frailty index. BMC Geriatr 2018;8:24.
46.
go back to reference Cabre M, Serra-Prat M, Force L, Almirall J, Palomera E, Clave P. Oropharyngeal dysphagia is a risk factor for readmission for pneumonia in the very elderly persons: observational prospective study. J Gerontol a Biol Sci Med Sci. 2014;69(3):330–7.PubMed Cabre M, Serra-Prat M, Force L, Almirall J, Palomera E, Clave P. Oropharyngeal dysphagia is a risk factor for readmission for pneumonia in the very elderly persons: observational prospective study. J Gerontol a Biol Sci Med Sci. 2014;69(3):330–7.PubMed
47.
go back to reference Wilmskoetter J, Simpson AN, Logan SL, Simpson KN, Bonilha HS. Impact of gastrostomy feeding tube placement on the 1-year trajectory of care in patients after stroke. Nutr Clin Pract. 2018;33(4):553–66.PubMed Wilmskoetter J, Simpson AN, Logan SL, Simpson KN, Bonilha HS. Impact of gastrostomy feeding tube placement on the 1-year trajectory of care in patients after stroke. Nutr Clin Pract. 2018;33(4):553–66.PubMed
48.
go back to reference Wou F, Gladman JR, Bradshaw L, Franklin M, Edmans J, Conroy SP. The predictive properties of frailty-rating scales in the acute medical unit. Age Ageing. 2013;42(6):776–81.PubMedPubMedCentral Wou F, Gladman JR, Bradshaw L, Franklin M, Edmans J, Conroy SP. The predictive properties of frailty-rating scales in the acute medical unit. Age Ageing. 2013;42(6):776–81.PubMedPubMedCentral
49.
go back to reference Segal JB, Huang J, Roth DL, Varadhan R. External validation of the claims-based frailty index in the national health and aging trends study cohort. Am J Epidemiol. 2017;186(6):745–7.PubMedPubMedCentral Segal JB, Huang J, Roth DL, Varadhan R. External validation of the claims-based frailty index in the national health and aging trends study cohort. Am J Epidemiol. 2017;186(6):745–7.PubMedPubMedCentral
50.
go back to reference Serra-Prat M, Hinojosa G, Lopez D, Juan M, Fabre E, Voss DS, Calvo M, Marta V, Ribo L, Palomera E, Arreola V, Clave P. Prevalence of oropharyngeal dysphagia and impaired safety and efficacy of swallow in independently living older persons. J Am Geriatr Soc. 2011;59:186–7.PubMed Serra-Prat M, Hinojosa G, Lopez D, Juan M, Fabre E, Voss DS, Calvo M, Marta V, Ribo L, Palomera E, Arreola V, Clave P. Prevalence of oropharyngeal dysphagia and impaired safety and efficacy of swallow in independently living older persons. J Am Geriatr Soc. 2011;59:186–7.PubMed
51.
go back to reference Fujishima I, Fuhu-Kurachi M, Arai H, et al. Sarcopenia and dysphagia: position paper by four professional organizations. Geriatr Gerontol Int. 2019;19(2):91–7.PubMed Fujishima I, Fuhu-Kurachi M, Arai H, et al. Sarcopenia and dysphagia: position paper by four professional organizations. Geriatr Gerontol Int. 2019;19(2):91–7.PubMed
52.
go back to reference Doggett DL, Tappe KA, Mitchell MD, Chapell R, Coates V, Turkelson CM. Prevention of pneumonia in elderly stroke patients by systematic diagnosis and treatment of dysphagia: an evidence-based comprehensive analysis of the literature. Dysphagia. 2001;16(4):279–95.PubMed Doggett DL, Tappe KA, Mitchell MD, Chapell R, Coates V, Turkelson CM. Prevention of pneumonia in elderly stroke patients by systematic diagnosis and treatment of dysphagia: an evidence-based comprehensive analysis of the literature. Dysphagia. 2001;16(4):279–95.PubMed
53.
go back to reference Hinchey JA, Shephard T, Furie K, et al. Stroke Practice Improvement Network I. Formal dysphagia screening protocols prevent pneumonia. Stroke 2005;36(9):1972–1976. Hinchey JA, Shephard T, Furie K, et al. Stroke Practice Improvement Network I. Formal dysphagia screening protocols prevent pneumonia. Stroke 2005;36(9):1972–1976.
54.
go back to reference Izaola I, Gomes Hoyos E, Lopez JJ, et al. The 10-item eating assessment tool is associated with nutritional status, mortality and hospital stay in elderly individuals requiring hospitalization with acute diseases. Nutr Hosp. 2018;35(4):827–32.PubMed Izaola I, Gomes Hoyos E, Lopez JJ, et al. The 10-item eating assessment tool is associated with nutritional status, mortality and hospital stay in elderly individuals requiring hospitalization with acute diseases. Nutr Hosp. 2018;35(4):827–32.PubMed
55.
go back to reference Troche MS, Okin MS, Rosenbek JC, et al. Aspiration and swallowing in Parkinson disease and rehabilitation with EMST: a randomized trial. Neurology. 2010;75(21):1912–9.PubMedPubMedCentral Troche MS, Okin MS, Rosenbek JC, et al. Aspiration and swallowing in Parkinson disease and rehabilitation with EMST: a randomized trial. Neurology. 2010;75(21):1912–9.PubMedPubMedCentral
56.
go back to reference Momasoaki R, Yasunaga H, Matsui H, Horiguchi H, Fushimi K, Abo M. Effect of dysphagia rehabilitation on oral intake in elderly patients with aspiration pneumonia. Geriatr Gerontol Int. 2015;15(6):694–9. Momasoaki R, Yasunaga H, Matsui H, Horiguchi H, Fushimi K, Abo M. Effect of dysphagia rehabilitation on oral intake in elderly patients with aspiration pneumonia. Geriatr Gerontol Int. 2015;15(6):694–9.
57.
go back to reference Carnaby G, Hankey GJ, Pizzi J. Behavioral intervention for dysphagia in acute stroke: a randomized controlled trial. Lancet Neurol. 2006;5(1):31–7.PubMed Carnaby G, Hankey GJ, Pizzi J. Behavioral intervention for dysphagia in acute stroke: a randomized controlled trial. Lancet Neurol. 2006;5(1):31–7.PubMed
58.
go back to reference Rogus-Pulia N, Rusche N, Hind JA, Zielinski J, Gangnon R, Safdar N, Robbins J. Effects of device-facilitated isometric progressive resistance oropharyngeal therapy on swallowing and health-related outcomes in nolder adults with dysphagia. J Am Geriatr Soc. 2016;64:417–24.PubMed Rogus-Pulia N, Rusche N, Hind JA, Zielinski J, Gangnon R, Safdar N, Robbins J. Effects of device-facilitated isometric progressive resistance oropharyngeal therapy on swallowing and health-related outcomes in nolder adults with dysphagia. J Am Geriatr Soc. 2016;64:417–24.PubMed
59.
go back to reference Speyer R, Baijens L, Heijnen M, Zwijnenberg I. Effects of therapy in oropharyngeal dysphagia by speech and language therapist: a systematic review. Dysphagia. 2010;25:40–65.PubMed Speyer R, Baijens L, Heijnen M, Zwijnenberg I. Effects of therapy in oropharyngeal dysphagia by speech and language therapist: a systematic review. Dysphagia. 2010;25:40–65.PubMed
60.
go back to reference Martin A, Ortega O, Roca M, Arus M, Clave P. Effect of a minimal-massive intervention in hospitalized older patients with oropharyngeal dysphagia: a proof of concept study. J Nutr Health Aging. 2018;22:739–47.PubMed Martin A, Ortega O, Roca M, Arus M, Clave P. Effect of a minimal-massive intervention in hospitalized older patients with oropharyngeal dysphagia: a proof of concept study. J Nutr Health Aging. 2018;22:739–47.PubMed
61.
go back to reference Hines S, Kynoch K, Munday J. Nursing interventions for identifying and managing acute dysphagia are effective for improving patient outcomes: a systematic review update. J Neurosci Nurs. 2016;48(4):215–23.PubMed Hines S, Kynoch K, Munday J. Nursing interventions for identifying and managing acute dysphagia are effective for improving patient outcomes: a systematic review update. J Neurosci Nurs. 2016;48(4):215–23.PubMed
62.
go back to reference Schneeweiss S, Avorn J. A review of uses of health care utilization databases for epidemiologic research on therapeutics. J Clin Epidemiol. 2005;58:323–37.PubMed Schneeweiss S, Avorn J. A review of uses of health care utilization databases for epidemiologic research on therapeutics. J Clin Epidemiol. 2005;58:323–37.PubMed
63.
go back to reference Romano PS, Mark DH. Bias in the coding of hospital discharge data and its implications for quality assessment. Med Care. 1994;32:81–90.PubMed Romano PS, Mark DH. Bias in the coding of hospital discharge data and its implications for quality assessment. Med Care. 1994;32:81–90.PubMed
64.
go back to reference Boss EF, Shah RK. An overview of administrative and national survey databases for use in otolaryngology research. Otolaryngol Head Neck Surg. 2013;148:711–6.PubMed Boss EF, Shah RK. An overview of administrative and national survey databases for use in otolaryngology research. Otolaryngol Head Neck Surg. 2013;148:711–6.PubMed
65.
go back to reference Quint JB. Health research data for the real world: The MarketScan® Databases. White Paper. Ann Arbor, Michigan: Truven Health Analytics; 2015. Quint JB. Health research data for the real world: The MarketScan® Databases. White Paper. Ann Arbor, Michigan: Truven Health Analytics; 2015.
66.
go back to reference Segal JB, Chang H-Y, Walston JD, Carlson MC, Varadhan R. Development of a claims-based frailty indicator anchored to a well-established frailty phenotype. Med Care. 2017;55(7):716–22.PubMedPubMedCentral Segal JB, Chang H-Y, Walston JD, Carlson MC, Varadhan R. Development of a claims-based frailty indicator anchored to a well-established frailty phenotype. Med Care. 2017;55(7):716–22.PubMedPubMedCentral
67.
go back to reference Kim DH, Schneeweiss S, Glynn RJ, Lipsitz LA, Rockwood K, Avorn J. Measuring frailty in Medicare data: development and validation of a claims-based frailty index. J Gerontol A Biol Sci Med Sci. 2018;73(7):980–7.PubMed Kim DH, Schneeweiss S, Glynn RJ, Lipsitz LA, Rockwood K, Avorn J. Measuring frailty in Medicare data: development and validation of a claims-based frailty index. J Gerontol A Biol Sci Med Sci. 2018;73(7):980–7.PubMed
Metadata
Title
Association Between Dysphagia and Inpatient Outcomes Across Frailty Level Among Patients ≥ 50 Years of Age
Authors
Seth M. Cohen
Deborah Lekan
Thomas Risoli Jr.
Hui-Jie Lee
Stephanie Misono
Heather E. Whitson
Sudha Raman
Publication date
01-10-2020
Publisher
Springer US
Published in
Dysphagia / Issue 5/2020
Print ISSN: 0179-051X
Electronic ISSN: 1432-0460
DOI
https://doi.org/10.1007/s00455-019-10084-z

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