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01-06-2014 | Case Report

Chemical pleurodesis using a Viscum album extract in infants with congenital chylothorax

Authors: Hwa Jin Cho, Kook Joo Na, Do Wan Kim, Young Earl Choi, Jae Sook Ma, In Seok Jeong

Published in: European Journal of Pediatrics | Issue 6/2014

Abstract

Congenital chylothorax is a rare condition, but it is the most common cause of pleural effusion in neonates and infants. Here, we report on the first trials of the intrapleural instillation of an extract of Viscum album (European mistletoe) (Abnobaviscum Q®) in two infants with congenital chylothorax that was refractory to standard conservative management and thoracic duct ligation. Conclusion: The clinical course of both children improved with no side effects related to the extract after following up the children for 2 years and 9 months, respectively. Randomized multicenter prospective studies will help determine the effectiveness of pleurodesis with a V. album extract and the occurrence of long-term side effects with this agent.

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Title: Chemical pleurodesis using a Viscum album extract in infants with congenital chylothorax
Authors: Hwa Jin Cho
Kook Joo Na
Do Wan Kim
Young Earl Choi
Jae Sook Ma
In Seok Jeong
Publication date: 01-06-2014
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Pediatrics / Issue 6/2014
Print ISSN: 0340-6199
Electronic ISSN: 1432-1076
DOI: https://doi.org/10.1007/s00431-014-2283-9

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Chemical pleurodesis using a Viscum album extract in infants with congenital chylothorax

Abstract

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Abstract

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