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European Journal of Pediatrics

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01-08-2009 | Original Paper

The influence of maternal smoking on maternal and newborn oxidant and antioxidant status

Authors: Filiz Simsek Orhon, Betül Ulukol, Didem Kahya, Bora Cengiz, Sevgi Başkan, Sevgi Tezcan

Published in: European Journal of Pediatrics | Issue 8/2009

Abstract

Background

Maternal smoking has been suggested as a source of oxidant stress in pregnant women and in newborns exposed in utero. The aim of this study was to determine the influence of maternal smoking on oxidant status and antioxidant vitamins of mother–infant pairs.

Materials and methods

Socioeconomic and diet characteristics were recorded from 20 smoker and 20 non-smoker pregnant women of 36 weeks’ gestation. On the day of delivery, venous blood samples of the women and cord bloods were taken. On postpartum day 7, milk and infant urine samples were collected. Plasma and milk β-carotene, retinol, α-tocopherol and cotinine levels, plasma malondialdehyde levels, and urine cotinine levels were measured.

Results

Milk α-tocopherol levels of smoking mothers were lower than those of non-smoking mothers. In smokers, there were no correlations between maternal vitamin A intakes and milk levels of retinol, and between maternal plasma levels and milk levels of β-carotene.

Conclusions

Maternal smoking may lead to decreased milk levels of vitamin E, as a result of making use of this antioxidant in order to limit lipid peroxidation, as well as may lead to a possible limitation on the transfer of lipophilic antioxidants including vitamin A from blood plasma to milk. Further investigations conducted in large populations will be needed to assess the effects of maternal smoking on the oxidant and antioxidant status of breast milk.

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Title: The influence of maternal smoking on maternal and newborn oxidant and antioxidant status
Authors: Filiz Simsek Orhon
Betül Ulukol
Didem Kahya
Bora Cengiz
Sevgi Başkan
Sevgi Tezcan
Publication date: 01-08-2009
Publisher: Springer-Verlag
Published in: European Journal of Pediatrics / Issue 8/2009
Print ISSN: 0340-6199
Electronic ISSN: 1432-1076
DOI: https://doi.org/10.1007/s00431-008-0873-0

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

The influence of maternal smoking on maternal and newborn oxidant and antioxidant status

Abstract

Background

Materials and methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Materials and methods

Results

Conclusions

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