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01-03-2008 | Short Report

TSH and endothelial function in children

Authors: Elena Gottardi, Flavio Egger, Giorgio Radetti

Published in: European Journal of Pediatrics | Issue 3/2008

Excerpt

The aim of this study was to determine whether endothelial function, which is altered in patients with hypothyroidism and returns to normal with replacement therapy, can be used as a sensitive marker of tissue hypothyroidism. Our results suggest that endothelial function is not correlated with thyroid stimulating hormone (TSH) and, therefore, that it is not a useful marker for determining when L-thyroxin should be started in subclinical hypothyroidism. …

Corretti MC, Anderson TJ, Benjamin EJ, Celermajer D, Charbonneau F, Creager MA, Deanfield J, Drexler H, Gerhard-Herman M, Herrington D, Vallance P, Vita J, Vogel R (2002) International Brachial Artery Reactivity Task Force: guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol 39:257–265PubMedCrossRef

Gharib H, Tuttle RM, Baskin HJ, Fish LH, Singer PA, McDermott MT, American Association of Clinical Endocrinologists, American Thyroid Association, The Endocrine Society (2005) Consensus Statement #1: subclinical thyroid dysfunction: a joint statement on management from the American Association of Clinical Endocrinologists, the American Thyroid Association, and The Endocrine Society. Thyroid 15:24–28PubMedCrossRef

Papaioannou GI, Lagasse M, Mather JF, Thompson PD (2004) Treating hypothyroidism improves endothelial function. Metabolism 53:278–279PubMedCrossRef

Surks MI, Ortiz E, Daniels GH, Sawin CT, Col NF, Cobin RH, Franklyn JA, Hershman JM, Burman KD, Denke MA, Gorman C, Cooper RS, Weissman NJ (2004) Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. JAMA 291:228–238PubMedCrossRef

Taddei S, Caraccio N, Virdis A, Dardano A, Versari D, Ghiadoni L, Ferrannini E, Salvetti A, Monzani F (2006) Low-grade systemic inflammation causes endothelial dysfunction in patients with Hashimoto’s thyroiditis. J Clin Endocrinol Metab 91:5076–5082PubMedCrossRef

Xiang GD, He YS, Zhao LS, Hou J, Yue L, Xiang HJ (2006) Impairment of endothelium-dependent arterial dilation in Hashimoto’s thyroiditis patients with euthyroidism. Clin Endocrinol 64:698–702CrossRef

Title: TSH and endothelial function in children
Authors: Elena Gottardi
Flavio Egger
Giorgio Radetti
Publication date: 01-03-2008
Publisher: Springer-Verlag
Published in: European Journal of Pediatrics / Issue 3/2008
Print ISSN: 0340-6199
Electronic ISSN: 1432-1076
DOI: https://doi.org/10.1007/s00431-007-0476-1

At a glance: The STEP trials

Springer Medicine

TSH and endothelial function in children

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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