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European Journal of Pediatrics
Published in: European Journal of Pediatrics 3/2005

01-03-2005 | Short Report

A neonate with macrosomia, cardiomyopathy and hepatomegaly born to an HIV-infected mother

Authors: Mieke H. Godfried, Kees Boer, Sabine Beuger, Henriëtte J. Scherpbier, Taco W. Kuijpers

Published in: European Journal of Pediatrics | Issue 3/2005

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Excerpt

Perinatal treatment with highly active antiretroviral drugs (HAART) is effective to prevent mother-to-child-transmission of HIV-1; however, adverse effects on the fetus may occur. We present a neonate with macrosomia, hypertrophic cardiomyopathy, and hepatomegaly, whose mother used HAART during pregnancy. …
Literature
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Anonymous (accessed May 2004) Public Health Service Task Force. Recommendations for use of anti-retroviral drugs in pregnant HIV-1-infected women for maternal health and interventions to reduce perinatal HIV-1 transmission in the United States. November 26 2003;http://​www.​aidsinfo.​nih.​gov
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Carr A (2003) HIV lipodystrophy: risk factors, pathogenesis, diagnosis and management. AIDS 17[Suppl 1]: S141–S148
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European Collaborative Study and the Swiss Mother + Child HIV cohort study (2000) Combination antiretroviral therapy and duration of pregnancy. AIDS 14: 2913–2920
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Hornberger LK, Lipschultz SE, Easley K, Colan, SD, Schwartz M, Kaplan S, Starc TJ, Ayres NA, Lai WW, Moodie DS, Kasten-Sportes C, Sanders SP (2000) Cardiac structure and function in fetuses of mothers infected with HIV: the prospective P2C2 HIV multicenter study. Am Heart J 140: 575–584CrossRef
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Poirier MC, Divi RL, Al-Harthi L, Olivero OA, Nguyen V, Walker B, Landay AL, Walker VE, Charurat M, Blattner WA (2003) Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers. J Acquired Immune Def Syndrome 33: 175–183CrossRef
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Tuomala RE, Shapiro DE, Mofenson LM, Bryson Y, Culnane M, Hughes MD, O’Sullivan MJ, Scott G, Stek AM, Wara D, Bulterys M (2002) Antiretroviral therapy during pregnancy and the risk of an adverse outcome. New Engl J Med 346: 1863–1870CrossRef
Metadata
Title
A neonate with macrosomia, cardiomyopathy and hepatomegaly born to an HIV-infected mother
Authors
Mieke H. Godfried
Kees Boer
Sabine Beuger
Henriëtte J. Scherpbier
Taco W. Kuijpers
Publication date
01-03-2005
Publisher
Springer-Verlag
Published in
European Journal of Pediatrics / Issue 3/2005
Print ISSN: 0340-6199
Electronic ISSN: 1432-1076
DOI
https://doi.org/10.1007/s00431-004-1609-4

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