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01-05-2020 | Review

Structural connectivity and functional properties of the macaque superior parietal lobule

Authors: Michela Gamberini, Lauretta Passarelli, Patrizia Fattori, Claudio Galletti

Published in: Brain Structure and Function | Issue 4/2020

Abstract

Despite the consolidated belief that the macaque superior parietal lobule (SPL) is entirely occupied by Brodmann’s area 5, recent data show that macaque SPL also hosts a large cortical region with structural and functional features similar to that of Brodmann’s area 7. According to these data, the anterior part of SPL is occupied by a somatosensory-dominated cortical region that hosts three architectural and functional distinct regions (PE, PEci, PEip) and the caudal half of SPL by a bimodal somato-visual region that hosts four areas: PEc, MIP, PGm, V6A. To date, the most studied areas of SPL are PE, PEc, and V6A. PE is essentially a high-order somatomotor area, while PEc and V6A are bimodal somatomotor–visuomotor areas, the former with predominant somatosensory input and the latter with predominant visual input. The functional properties of these areas and their anatomical connectivity strongly suggest their involvement in the control of limb movements. PE is suggested to be involved in the preparation/execution of limb movements, in particular, the movements of the upper limb; PEc in the control of movements of both upper and lower limbs, as well as in their interaction with the visual environment; V6A in the control of reach-to-grasp movements performed with the upper limb. In humans, SPL is traditionally considered to have a different organization with respect to macaques. Here, we review several lines of evidence suggesting that this is not the case, showing a similar structure for human and non-human primate SPLs.

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Title: Structural connectivity and functional properties of the macaque superior parietal lobule
Authors: Michela Gamberini
Lauretta Passarelli
Patrizia Fattori
Claudio Galletti
Publication date: 01-05-2020
Publisher: Springer Berlin Heidelberg
Published in: Brain Structure and Function / Issue 4/2020
Print ISSN: 1863-2653
Electronic ISSN: 1863-2661
DOI: https://doi.org/10.1007/s00429-019-01976-9

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Structural connectivity and functional properties of the macaque superior parietal lobule

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