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Open Access 01-04-2019 | Original Article

Concurrent analysis of white matter bundles and grey matter networks in the chimpanzee

Authors: Rogier B. Mars, Jonathan O’Muircheartaigh, Davide Folloni, Longchuan Li, Matthew F. Glasser, Saad Jbabdi, Katherine L. Bryant

Published in: Brain Structure and Function | Issue 3/2019

Abstract

Understanding the phylogeny of the human brain requires an appreciation of brain organization of our closest animal relatives. Neuroimaging tools such as magnetic resonance imaging (MRI) allow us to study whole-brain organization in species which can otherwise not be studied. Here, we used diffusion MRI to reconstruct the connections of the cortical hemispheres of the chimpanzee. This allowed us to perform an exploratory analysis of the grey matter structures of the chimpanzee cerebral cortex and their underlying white matter connectivity profiles. We identified a number of networks that strongly resemble those found in other primates, including the corticospinal system, limbic connections through the cingulum bundle and fornix, and occipital–temporal and temporal–frontal systems. Notably, chimpanzee temporal cortex showed a strong resemblance to that of the human brain, providing some insight into the specialization of the two species’ shared lineage.

Human in vivo diffusion MRI data were provided by the Human Connectome Project (HCP), WU-Minn Consortium (Principal Investigators: David Van Essen and Kamil Ugurbil; 1U54MH091657) funded by the 16 NIH Institutes and Centers that support the NIH Blueprint for Neuroscience Research; and by the McDonnell Center for Systems Neuroscience at Washington University (Van Essen et al. 2013). Minimally preprocessed datasets from the Q2 public data release were used. Data acquisition and preprocessing methods are detailed in Uğurbil et al. (2013), Sotiropoulos et al. (2013), and Glasser et al. (2013).

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Title: Concurrent analysis of white matter bundles and grey matter networks in the chimpanzee
Authors: Rogier B. Mars
Jonathan O’Muircheartaigh
Davide Folloni
Longchuan Li
Matthew F. Glasser
Saad Jbabdi
Katherine L. Bryant
Publication date: 01-04-2019
Publisher: Springer Berlin Heidelberg
Published in: Brain Structure and Function / Issue 3/2019
Print ISSN: 1863-2653
Electronic ISSN: 1863-2661
DOI: https://doi.org/10.1007/s00429-018-1817-8

At a glance: The STEP trials

Springer Medicine

Concurrent analysis of white matter bundles and grey matter networks in the chimpanzee

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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