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Virchows Archiv
Published in: Virchows Archiv 4/2022

Open Access 01-04-2022 | Metastasis | Brief Report

Evolution of superficial spreading melanoma to resemble desmoplastic melanoma: case report

Authors: Martin G. Cook, Barry W. E. M. Powell, Megan E. Grant, Adele C. Green

Published in: Virchows Archiv | Issue 4/2022

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Abstract

Desmoplastic melanoma commonly occurs on the head and neck in a pure form, but occasionally, it occurs in a mixed tumor with another type, usually superficial spreading melanoma (SSM), and rarely as a metastasis from a primary SSM. We report here a primary SSM on the leg of a 32-year-old male which metastasised to lymph nodes, and 10 years later recurred at the primary site initially with mixed features but evolving to resemble a uniformly desmoplastic, deeply invasive melanoma. This unusual case has implications for clinical management and is additionally notable for its reversal in behavior, from metastatic to local infiltrative type, correlating with the change in morphology.
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Metadata
Title
Evolution of superficial spreading melanoma to resemble desmoplastic melanoma: case report
Authors
Martin G. Cook
Barry W. E. M. Powell
Megan E. Grant
Adele C. Green
Publication date
01-04-2022
Publisher
Springer Berlin Heidelberg
Published in
Virchows Archiv / Issue 4/2022
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-021-03127-0

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