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Published in: Virchows Archiv 2/2017

01-08-2017 | Invited Annual Review Issue

Colorectal cancer molecular profiling: from IHC to NGS in search of optimal algorithm

Authors: Larissa V. Furtado, Wade S. Samowitz

Published in: Virchows Archiv | Issue 2/2017

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Abstract

Advances in defining the mutational landscape of colorectal cancer (CRC) over the past decades have revolutionized the molecular understanding and clinical testing algorithms for this disease. Mutation testing is standard of care for the work-up of CRCs. This review focuses on the current indications and strategies for molecular testing in CRC and discusses the potential changes in CRC testing approach associated with the emerging clinical application of genomic-based technologies.
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Metadata
Title
Colorectal cancer molecular profiling: from IHC to NGS in search of optimal algorithm
Authors
Larissa V. Furtado
Wade S. Samowitz
Publication date
01-08-2017
Publisher
Springer Berlin Heidelberg
Published in
Virchows Archiv / Issue 2/2017
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-017-2153-8

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