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01-05-2008 | Case Report

Report of a metaplastic carcinoma of the breast with multi-directional differentiation: an adenoid cystic carcinoma, a spindle cell carcinoma and melanoma

Authors: Aurelia Noske, Michael Schwabe, Stefan Pahl, Eva Fallenberg, Christiane Richter-Ehrenstein, Manfred Dietel, Glen Kristiansen

Published in: Virchows Archiv | Issue 5/2008

Abstract

Metaplastic carcinoma of the breast is a heterogeneous neoplasia, generally composed of both epithelial and mesenchymal components. We report an unusual case of mammary metaplastic carcinoma in a 51-year-old female patient. Needle core biopsy from the tumour mass showed malignant epithelial and sarcomatous features. The resection specimen revealed a multi-directional tumour differentiation consisting predominantly of: firstly, a poorly differentiated basaloid epithelial cell type, consistent with an adenoid cystic carcinoma; secondly, areas of a spindle cell carcinoma; and, thirdly, areas with a melanocytic differentiation. This is the first report on a metaplastic carcinoma of the breast presenting as an admixture of an adenoid cystic carcinoma and melanoma.

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Title: Report of a metaplastic carcinoma of the breast with multi-directional differentiation: an adenoid cystic carcinoma, a spindle cell carcinoma and melanoma
Authors: Aurelia Noske
Michael Schwabe
Stefan Pahl
Eva Fallenberg
Christiane Richter-Ehrenstein
Manfred Dietel
Glen Kristiansen
Publication date: 01-05-2008
Publisher: Springer-Verlag
Published in: Virchows Archiv / Issue 5/2008
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI: https://doi.org/10.1007/s00428-008-0588-7

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Report of a metaplastic carcinoma of the breast with multi-directional differentiation: an adenoid cystic carcinoma, a spindle cell carcinoma and melanoma

Abstract

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

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