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Virchows Archiv
Published in: Virchows Archiv 6/2007

01-12-2007 | Case Report

Isolated vasculitis of the female genital tract: a case series and review of literature

Authors: Emmanuel Hoppé, Louis-Rémi de Ybarlucéa, Jacky Collet, Jérome Dupont, Bettina Fabiani, Xavier Puéchal

Published in: Virchows Archiv | Issue 6/2007

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Abstract

To provide a clinicopathologic review of vasculitis confined to the female genital tract, we describe three cases, and we searched PubMed from 1965 to 2006 with analysis of all relevant articles. We identified 118 additional cases in the literature of whom 108 had isolated necrotizing vasculitis similar to classical polyarteritis nodosa (PAN-type), and 10 presented isolated giant cell arteritis (GCA-type) of the female genital tract. In most cases, arteritis was discovered surprisingly. The mean age of these patients was 48.6 years for the PAN-type and 64.1 for the GCA-type. Vasculitis affected a single organ in 88 (81.5%) cases of which 71 (65.7%) involved the cervix in the PAN-type, whereas it was limited in the myometrium in five (50%) cases in the GCA-type. There was no progression to a systemic vasculitis in 99.1% of the cases. A comparable favorable outcome was reported after surgery in all cases with a mean follow-up of 40.8 months. We conclude that isolated vasculitis of the female genital tract is a distinct condition, with two different patterns but a similar favorable outcome after resection. Its knowledge is needed to avoid aggressive evaluation and therapy.
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Metadata
Title
Isolated vasculitis of the female genital tract: a case series and review of literature
Authors
Emmanuel Hoppé
Louis-Rémi de Ybarlucéa
Jacky Collet
Jérome Dupont
Bettina Fabiani
Xavier Puéchal
Publication date
01-12-2007
Publisher
Springer-Verlag
Published in
Virchows Archiv / Issue 6/2007
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-007-0514-4

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