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Virchows Archiv
Published in: Virchows Archiv 5/2007

Open Access 01-11-2007 | Review and Perspective

Pancreatic intraductal papillary-mucinous neoplasms: a new and evolving entity

Authors: Snezana Andrejevic-Blant, Markus Kosmahl, Bence Sipos, Günter Klöppel

Published in: Virchows Archiv | Issue 5/2007

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Abstract

For a long time, intraductal tumors of the pancreas were neglected because they were misdiagnosed as mucinous cystadenocarcinoma, ordinary ductal adenocarcinoma, or chronic pancreatitis. Only in recent years have they been recognized as clinical and pathological entities. Most common are the intraductal papillary-mucinous neoplasms. Although they show an adenoma-carcinoma sequence, they have proved to have a more favorable prognosis than ductal adenocarcinoma, when resected in a preinvasive state. Recently, it has become clear that they constitute a heterogeneous group with at least four subtypes. Their stratification reveals that the various intraductal papillary-mucinous neoplasm subtypes have different biological properties with different prognostic implications.
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Metadata
Title
Pancreatic intraductal papillary-mucinous neoplasms: a new and evolving entity
Authors
Snezana Andrejevic-Blant
Markus Kosmahl
Bence Sipos
Günter Klöppel
Publication date
01-11-2007
Publisher
Springer-Verlag
Published in
Virchows Archiv / Issue 5/2007
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-007-0512-6

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