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Virchows Archiv
Published in: Virchows Archiv 2/2007

01-02-2007 | Letter to the Editor

Expression of epidermal growth factor receptor (EGFR) is frequent in inflammatory bowel disease (IBD)-associated intestinal cancer

Authors: Magali Svrcek, Jacques Cosnes, Emmanuel Tiret, Malika Bennis, Yann Parc, Jean-François Fléjou

Published in: Virchows Archiv | Issue 2/2007

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Excerpt

Sir, …
Literature
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Alexander RJ, Panja A, Kaplan-Liss E, Mayer L, Raicht RF (1995) Expression of growth factor receptor-encoded mRNA by colonic epithelial cells is altered in inflammatory bowel disease. Dig Dis Sci 40:485–494PubMedCrossRef
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Chung KY, Shia J, Kemeny NE, Shah M, Schwartz GK, Tse A, Hamilton A, Pan D, Schrag D, Schwartz L, Klimstra DS, Fridman D, Kelsen DP, Saltz LB (2005) Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry. J Clin Oncol 23:1803–1810PubMedCrossRef
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Ciardiello F, Tortora G (2003) Epidermal growth factor receptor (EGFR) as a target in cancer therapy: understanding the role of receptor expression and other molecular determinants that could influence the response to anti-EGFR drugs. Eur J Cancer 39:1348–1354PubMedCrossRef
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Cunningham D, Humblet Y, Siena S, Khayat D, Bleiberg H, Santoro A, Bets D, Mueser M, Harstrick A, Verslype C, Chau I, Van Cutsem E (2004) Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 351:337–345PubMedCrossRef
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Goldstein NS, Armin M (2001) Epidermal growth factor receptor immunohistochemical reactivity in patients with American Joint Committee on Cancer stage IV colon adenocarcinoma: implications for a standardized scoring system. Cancer 92:1331–1346PubMedCrossRef
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O’Dwyer PJ, Benson AB (2002) Epidermal growth factor receptor-targeted therapy in colorectal cancer. Semin Oncol 29:10–17 (Suppl)PubMedCrossRef
Metadata
Title
Expression of epidermal growth factor receptor (EGFR) is frequent in inflammatory bowel disease (IBD)-associated intestinal cancer
Authors
Magali Svrcek
Jacques Cosnes
Emmanuel Tiret
Malika Bennis
Yann Parc
Jean-François Fléjou
Publication date
01-02-2007
Publisher
Springer-Verlag
Published in
Virchows Archiv / Issue 2/2007
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-006-0338-7

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