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Published in: Virchows Archiv 2/2006

01-08-2006 | Case Report

An unusual case of malignant pilocytic astrocytoma occurring in the eye

Authors: Alessandra Canesso, Marina Gardiman, Roberto Salmaso, Rita Alaggio, Vito Ninfo

Published in: Virchows Archiv | Issue 2/2006

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Abstract

Pilocytic astrocytoma is a central nervous system neoplasia that arises during pediatric age. Only few cases have been documented in patients older than 50 years old. It is a low-grade lesion that can rarely undergo malignant changes presenting the histologic features of a high-grade glioma. We report a case of a pilocytic astrocytoma arising in the eyeball of a 53-year-old man affected by glaucoma that underwent malignant evolution.
Literature
1.
go back to reference Alpers CE, Davis RL, Wilson CB (1982) Persistence and late malignant transformation of childhood cerebellar astrocytoma. Case report. J Neurosurg 57:548–551PubMed Alpers CE, Davis RL, Wilson CB (1982) Persistence and late malignant transformation of childhood cerebellar astrocytoma. Case report. J Neurosurg 57:548–551PubMed
2.
go back to reference Bernell WR, Kepes JJ, Seitz EP (1972) Late malignant recurrence of childhood cerebellar astrocytoma. Report of two cases. J Neurosurg 37:470–474PubMed Bernell WR, Kepes JJ, Seitz EP (1972) Late malignant recurrence of childhood cerebellar astrocytoma. Report of two cases. J Neurosurg 37:470–474PubMed
3.
go back to reference Budka H (1975) Partially resected and irradiated cerebellar astrocytoma of childhood: malignant evolution after 28 years. Acta Neurochir (Wien) 32(1–2):139–146, AbstractCrossRef Budka H (1975) Partially resected and irradiated cerebellar astrocytoma of childhood: malignant evolution after 28 years. Acta Neurochir (Wien) 32(1–2):139–146, AbstractCrossRef
4.
go back to reference Burger PC, Scheithauer BW (ed) (1994) Atlas of tumors pathology: tumors of the central nervous system. Armed Forces Institute of Pathology, Washington, DC, pp 77–96 Burger PC, Scheithauer BW (ed) (1994) Atlas of tumors pathology: tumors of the central nervous system. Armed Forces Institute of Pathology, Washington, DC, pp 77–96
5.
go back to reference Dei Tos AP, Seregard S, Calonje E et al (1995) Giant cell angiofibroma a distinctive orbital tumor in adults. Am J Surg Pathol 19(11):1286–1293PubMed Dei Tos AP, Seregard S, Calonje E et al (1995) Giant cell angiofibroma a distinctive orbital tumor in adults. Am J Surg Pathol 19(11):1286–1293PubMed
6.
go back to reference Dirks PB, Jay V, Becker LE et al (1994) Development of anaplastic changes in low grade astrocytomas of childhood. Neurosurgery 34(1):68–78PubMedCrossRef Dirks PB, Jay V, Becker LE et al (1994) Development of anaplastic changes in low grade astrocytomas of childhood. Neurosurgery 34(1):68–78PubMedCrossRef
7.
go back to reference Kleinman GM, Schoene WC, Walshe TM et al (1978) Malignant transformation in benign cerebellar astrocytoma. Case report. J Neurosurg 49:111–118PubMedCrossRef Kleinman GM, Schoene WC, Walshe TM et al (1978) Malignant transformation in benign cerebellar astrocytoma. Case report. J Neurosurg 49:111–118PubMedCrossRef
8.
go back to reference Marquardt MD, Zimmerman LE (1982) Histopathology of meningiomas and gliomas of the optic nerve. Human Pathol 13(1):226–235CrossRef Marquardt MD, Zimmerman LE (1982) Histopathology of meningiomas and gliomas of the optic nerve. Human Pathol 13(1):226–235CrossRef
9.
go back to reference Nishio S, Takeshita I, Fukui M et al (1988) Anaplastic evolution of childhood optico-hypothalamic pilocytic astrocytoma: report of an autopsy case. Clin Neuropathol 7(5):254–258PubMed Nishio S, Takeshita I, Fukui M et al (1988) Anaplastic evolution of childhood optico-hypothalamic pilocytic astrocytoma: report of an autopsy case. Clin Neuropathol 7(5):254–258PubMed
10.
go back to reference Rosai J (2004) Rosai and Ackerman’s surgical pathology, vol 2, pp 2725–2730 Rosai J (2004) Rosai and Ackerman’s surgical pathology, vol 2, pp 2725–2730
11.
go back to reference Sasaki A, Yoshida S, Kurihara H et al (2001) Glioblastoma with large numbers of eosinophilic hyaline droplets in neoplastic astrocytes. Clin Neuropathol 20(4):156–162PubMed Sasaki A, Yoshida S, Kurihara H et al (2001) Glioblastoma with large numbers of eosinophilic hyaline droplets in neoplastic astrocytes. Clin Neuropathol 20(4):156–162PubMed
12.
go back to reference Schwartz AM, Ghatak NR (1990) Malignant transformation of benign cerebellar astrocytoma. Cancer 65:333–336PubMedCrossRef Schwartz AM, Ghatak NR (1990) Malignant transformation of benign cerebellar astrocytoma. Cancer 65:333–336PubMedCrossRef
13.
go back to reference Yukitaka U, Norio A, Toshiki Y et al (1987) Malignant recurrence of childhood cerebellar astrocytoma: case report. Neurosurgery 21(2):251–255PubMedCrossRef Yukitaka U, Norio A, Toshiki Y et al (1987) Malignant recurrence of childhood cerebellar astrocytoma: case report. Neurosurgery 21(2):251–255PubMedCrossRef
14.
go back to reference WHO Classification of Tumors (ed) (2000) Pathology and genetic of tumors of the nervous system. IARC Press, Lyon, pp 47–49 WHO Classification of Tumors (ed) (2000) Pathology and genetic of tumors of the nervous system. IARC Press, Lyon, pp 47–49
15.
go back to reference Wilson WB, Feinsod M, Hoyt WF et al (1976) Malignant evolution of childhood chiasmal pilocytic astrocytoma. Neurology 26:322–325PubMedCrossRef Wilson WB, Feinsod M, Hoyt WF et al (1976) Malignant evolution of childhood chiasmal pilocytic astrocytoma. Neurology 26:322–325PubMedCrossRef
Metadata
Title
An unusual case of malignant pilocytic astrocytoma occurring in the eye
Authors
Alessandra Canesso
Marina Gardiman
Roberto Salmaso
Rita Alaggio
Vito Ninfo
Publication date
01-08-2006
Publisher
Springer-Verlag
Published in
Virchows Archiv / Issue 2/2006
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI
https://doi.org/10.1007/s00428-006-0224-3

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