Skip to main content
Top
Published in: Langenbeck's Archives of Surgery 5/2016

01-08-2016 | REVIEW ARTICLE

Benefit of mechanical bowel preparation prior to elective colorectal surgery: current insights

Authors: A. C. A. Murray, R. P. Kiran

Published in: Langenbeck's Archives of Surgery | Issue 5/2016

Login to get access

Abstract

Background

Back in the 1970s, the administration of oral antibiotics combined with mechanical bowel preparation prior to colorectal surgery was considered standard procedure and adopted widely. Subsequent evidence suggested that bowel cleansing was unnecessary, even harmful, and hence was abandoned. Most recent evidence, however, suggests that full preparation significantly improves a spectrum of colectomy-specific postoperative outcomes.

Purpose

The purpose of this review was to describe existing literature regarding the optimal bowel preparation regimen prior to elective colorectal resection. In addition, we evaluate the available evidence on each component—oral antibiotics, mechanical bowel preparation and intravenous antibiotics, with regard to short-term postoperative outcomes.

Conclusions

Current best evidence suggests that colorectal resection should be preceded by a combination of oral antibiotics, mechanical bowel preparation and intravenous antibiotics at induction. Further randomized controlled trials are required due to a paucity of level 1 evidence.
Literature
1.
go back to reference Prevention C-CfDCa (2007) The direct medical costs of healthcare-associated infections in U.S. Hospitals and the benefits of prevention Prevention C-CfDCa (2007) The direct medical costs of healthcare-associated infections in U.S. Hospitals and the benefits of prevention
2.
go back to reference Prevention C-CfDCa (2016) Healthcare associated infections March 2 Prevention C-CfDCa (2016) Healthcare associated infections March 2
3.
go back to reference Zimlichman E, Henderson D, Tamir O et al (2013) Health care-associated infections: a meta-analysis of costs and financial impact on the US health care system. JAMA Intern Med 173(22):2039–2046, Dec 9–23CrossRefPubMed Zimlichman E, Henderson D, Tamir O et al (2013) Health care-associated infections: a meta-analysis of costs and financial impact on the US health care system. JAMA Intern Med 173(22):2039–2046, Dec 9–23CrossRefPubMed
4.
go back to reference Wick EC, Vogel JD, Church JM, Remzi F, Fazio VW (2009) Surgical site infections in a “high outlier” institution: are colorectal surgeons to blame? Dis Colon Rectum 52(3):374–379CrossRefPubMed Wick EC, Vogel JD, Church JM, Remzi F, Fazio VW (2009) Surgical site infections in a “high outlier” institution: are colorectal surgeons to blame? Dis Colon Rectum 52(3):374–379CrossRefPubMed
5.
go back to reference Kirkland KB, Briggs JP, Trivette SL, Wilkinson WE, Sexton DJ (1999) The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol 20(11):725–730CrossRefPubMed Kirkland KB, Briggs JP, Trivette SL, Wilkinson WE, Sexton DJ (1999) The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol 20(11):725–730CrossRefPubMed
6.
go back to reference Ws H (1887) Circular suture of the intestine–an experimental study. Am J Med Sci 94:436 Ws H (1887) Circular suture of the intestine–an experimental study. Am J Med Sci 94:436
7.
go back to reference Nichols RL, Condon RE (1971) Preoperative preparation of the colon. Surg Gynecol Obstet 132(2):323–337PubMed Nichols RL, Condon RE (1971) Preoperative preparation of the colon. Surg Gynecol Obstet 132(2):323–337PubMed
8.
9.
go back to reference Irvin TT, Goligher JC (1973) Aetiology of disruption of intestinal anastomoses. Br J Surg 60(6):461–464CrossRefPubMed Irvin TT, Goligher JC (1973) Aetiology of disruption of intestinal anastomoses. Br J Surg 60(6):461–464CrossRefPubMed
10.
go back to reference Fry DE (2016) Antimicrobial bowel preparation for elective colon surgery. Surg Infect. Feb 17 Fry DE (2016) Antimicrobial bowel preparation for elective colon surgery. Surg Infect. Feb 17
11.
go back to reference Garlock JH (1939) SGP. The use of sulfanilamide in surgery of the colon and rectum. Preliminary report. Surgery 5(5):787–790 Garlock JH (1939) SGP. The use of sulfanilamide in surgery of the colon and rectum. Preliminary report. Surgery 5(5):787–790
12.
go back to reference Solla JA, Rothenberger DA (1990) Preoperative bowel preparation. A survey of colon and rectal surgeons. Dis Colon Rectum 33(2):154–159CrossRefPubMed Solla JA, Rothenberger DA (1990) Preoperative bowel preparation. A survey of colon and rectal surgeons. Dis Colon Rectum 33(2):154–159CrossRefPubMed
13.
go back to reference Markell KW, Hunt BM, Charron PD et al (2010) Prophylaxis and management of wound infections after elective colorectal surgery: a survey of the American Society of Colon and Rectal Surgeons membership. J Gastrointest Surg : Off J Soc Surg Alimentary Tract 14(7):1090–1098CrossRef Markell KW, Hunt BM, Charron PD et al (2010) Prophylaxis and management of wound infections after elective colorectal surgery: a survey of the American Society of Colon and Rectal Surgeons membership. J Gastrointest Surg : Off J Soc Surg Alimentary Tract 14(7):1090–1098CrossRef
16.
go back to reference Althumairi AA, Canner JK, Pawlik TM, et al (2016) Benefits of bowel preparation beyond surgical site infection: a retrospective study. Ann Surg. Jan 12 Althumairi AA, Canner JK, Pawlik TM, et al (2016) Benefits of bowel preparation beyond surgical site infection: a retrospective study. Ann Surg. Jan 12
17.
go back to reference Kiran RP, Murray AC, Chiuzan C, Estrada D, Forde K (2015) Combined preoperative mechanical bowel preparation with oral antibiotics significantly reduces surgical site infection, anastomotic leak, and ileus after colorectal surgery. Ann Surg 262(3):416–425, discussion 423–415CrossRefPubMed Kiran RP, Murray AC, Chiuzan C, Estrada D, Forde K (2015) Combined preoperative mechanical bowel preparation with oral antibiotics significantly reduces surgical site infection, anastomotic leak, and ileus after colorectal surgery. Ann Surg 262(3):416–425, discussion 423–415CrossRefPubMed
18.
go back to reference Kim EK, Sheetz KH, Bonn J et al (2014) A statewide colectomy experience: the role of full bowel preparation in preventing surgical site infection. Ann Surg 259(2):310–314CrossRefPubMed Kim EK, Sheetz KH, Bonn J et al (2014) A statewide colectomy experience: the role of full bowel preparation in preventing surgical site infection. Ann Surg 259(2):310–314CrossRefPubMed
20.
go back to reference Nichols RL, Condon RE (1975) Role of the endogenous gastrointestinal microflora in postoperative wound sepsis. Surg Annu 7:279–293PubMed Nichols RL, Condon RE (1975) Role of the endogenous gastrointestinal microflora in postoperative wound sepsis. Surg Annu 7:279–293PubMed
21.
go back to reference Lewis RT (2002) Oral versus systemic antibiotic prophylaxis in elective colon surgery: a randomized study and meta-analysis send a message from the 1990s. Can J Surg Journal Canadien de Chirurgie 45(3):173–180PubMed Lewis RT (2002) Oral versus systemic antibiotic prophylaxis in elective colon surgery: a randomized study and meta-analysis send a message from the 1990s. Can J Surg Journal Canadien de Chirurgie 45(3):173–180PubMed
22.
go back to reference Greco M, Capretti G, Beretta L, Gemma M, Pecorelli N, Braga M (2014) Enhanced recovery program in colorectal surgery: a meta-analysis of randomized controlled trials. World J Surg 38(6):1531–1541CrossRefPubMed Greco M, Capretti G, Beretta L, Gemma M, Pecorelli N, Braga M (2014) Enhanced recovery program in colorectal surgery: a meta-analysis of randomized controlled trials. World J Surg 38(6):1531–1541CrossRefPubMed
23.
go back to reference Gustafsson UO, Scott MJ, Schwenk W et al (2013) Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS((R))) Society recommendations. World J Surg 37(2):259–284CrossRefPubMed Gustafsson UO, Scott MJ, Schwenk W et al (2013) Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS((R))) Society recommendations. World J Surg 37(2):259–284CrossRefPubMed
24.
go back to reference Eskicioglu C, Forbes SS, Fenech DS, McLeod RS (2010) Preoperative bowel preparation for patients undergoing elective colorectal surgery: a clinical practice guideline endorsed by the Canadian Society of Colon and Rectal Surgeons. Can J Surg Journal canadien de chirurgie 53(6):385–395PubMed Eskicioglu C, Forbes SS, Fenech DS, McLeod RS (2010) Preoperative bowel preparation for patients undergoing elective colorectal surgery: a clinical practice guideline endorsed by the Canadian Society of Colon and Rectal Surgeons. Can J Surg Journal canadien de chirurgie 53(6):385–395PubMed
26.
go back to reference Bucher P, Gervaz P, Soravia C, Mermillod B, Erne M, Morel P (2005) Randomized clinical trial of mechanical bowel preparation versus no preparation before elective left-sided colorectal surgery. Br J Surg 92(4):409–414CrossRefPubMed Bucher P, Gervaz P, Soravia C, Mermillod B, Erne M, Morel P (2005) Randomized clinical trial of mechanical bowel preparation versus no preparation before elective left-sided colorectal surgery. Br J Surg 92(4):409–414CrossRefPubMed
27.
go back to reference Guenaga KF, Matos D, Wille-Jorgensen P (2011) Mechanical bowel preparation for elective colorectal surgery. Cochrane Database Syst Rev (9):Cd001544 Guenaga KF, Matos D, Wille-Jorgensen P (2011) Mechanical bowel preparation for elective colorectal surgery. Cochrane Database Syst Rev (9):Cd001544
28.
go back to reference Santos JC Jr, Batista J, Sirimarco MT, Guimaraes AS, Levy CE (1994) Prospective randomized trial of mechanical bowel preparation in patients undergoing elective colorectal surgery. Br J Surg 81(11):1673–1676CrossRefPubMed Santos JC Jr, Batista J, Sirimarco MT, Guimaraes AS, Levy CE (1994) Prospective randomized trial of mechanical bowel preparation in patients undergoing elective colorectal surgery. Br J Surg 81(11):1673–1676CrossRefPubMed
29.
go back to reference Contant CM, Hop WC, van’t Sant HP et al (2007) Mechanical bowel preparation for elective colorectal surgery: a multicentre randomised trial. Lancet 370(9605):2112–2117CrossRefPubMed Contant CM, Hop WC, van’t Sant HP et al (2007) Mechanical bowel preparation for elective colorectal surgery: a multicentre randomised trial. Lancet 370(9605):2112–2117CrossRefPubMed
30.
go back to reference Slim K, Vicaut E, Panis Y, Chipponi J (2004) Meta-analysis of randomized clinical trials of colorectal surgery with or without mechanical bowel preparation. Br J Surg 91(9):1125–1130CrossRefPubMed Slim K, Vicaut E, Panis Y, Chipponi J (2004) Meta-analysis of randomized clinical trials of colorectal surgery with or without mechanical bowel preparation. Br J Surg 91(9):1125–1130CrossRefPubMed
31.
go back to reference Slim K, Vicaut E, Launay-Savary MV, Contant C, Chipponi J (2009) Updated systematic review and meta-analysis of randomized clinical trials on the role of mechanical bowel preparation before colorectal surgery. Ann Surg 249(2):203–209CrossRefPubMed Slim K, Vicaut E, Launay-Savary MV, Contant C, Chipponi J (2009) Updated systematic review and meta-analysis of randomized clinical trials on the role of mechanical bowel preparation before colorectal surgery. Ann Surg 249(2):203–209CrossRefPubMed
32.
go back to reference Courtney DE, Kelly ME, Burke JP, Winter DC (2015) Postoperative outcomes following mechanical bowel preparation before proctectomy: a meta-analysis. Color Dis : Off J Assoc Coloproctol G B Irel 17(10):862–869CrossRef Courtney DE, Kelly ME, Burke JP, Winter DC (2015) Postoperative outcomes following mechanical bowel preparation before proctectomy: a meta-analysis. Color Dis : Off J Assoc Coloproctol G B Irel 17(10):862–869CrossRef
33.
go back to reference Pittet O, Nocito A, Balke H et al (2015) Rectal enema is an alternative to full mechanical bowel preparation for primary rectal cancer surgery. Color Dis : Off J Assoc Coloproctol G B Irel 17(11):1007–1010CrossRef Pittet O, Nocito A, Balke H et al (2015) Rectal enema is an alternative to full mechanical bowel preparation for primary rectal cancer surgery. Color Dis : Off J Assoc Coloproctol G B Irel 17(11):1007–1010CrossRef
34.
go back to reference Van’t Sant HP, Weidema WF, Hop WC, Oostvogel HJ, Contant CM (2010) The influence of mechanical bowel preparation in elective lower colorectal surgery. Ann Surg 251(1):59–63CrossRef Van’t Sant HP, Weidema WF, Hop WC, Oostvogel HJ, Contant CM (2010) The influence of mechanical bowel preparation in elective lower colorectal surgery. Ann Surg 251(1):59–63CrossRef
35.
go back to reference Van’t Sant HP, Slieker JC, Hop WC et al (2012) The influence of mechanical bowel preparation in elective colorectal surgery for diverticulitis. Tech Coloproctol 16(4):309–314CrossRef Van’t Sant HP, Slieker JC, Hop WC et al (2012) The influence of mechanical bowel preparation in elective colorectal surgery for diverticulitis. Tech Coloproctol 16(4):309–314CrossRef
36.
go back to reference Bretagnol F, Alves A, Ricci A, Valleur P, Panis Y (2007) Rectal cancer surgery without mechanical bowel preparation. B J Surg 94(10):1266–1271CrossRef Bretagnol F, Alves A, Ricci A, Valleur P, Panis Y (2007) Rectal cancer surgery without mechanical bowel preparation. B J Surg 94(10):1266–1271CrossRef
37.
go back to reference Allaix ME, Arolfo S, Degiuli M, Giraudo G, Volpatto S, Morino M (2015) Laparoscopic colon resection: To prep or not to prep? Analysis of 1535 patients. Surg Endoscopy. Aug 25 Allaix ME, Arolfo S, Degiuli M, Giraudo G, Volpatto S, Morino M (2015) Laparoscopic colon resection: To prep or not to prep? Analysis of 1535 patients. Surg Endoscopy. Aug 25
38.
go back to reference Sasaki J, Matsumoto S, Kan H et al (2012) Objective assessment of postoperative gastrointestinal motility in elective colonic resection using a radiopaque marker provides an evidence for the abandonment of preoperative mechanical bowel preparation. J Nippon Med Sch = Nippon Ika Daigaku zasshi 79(4):259–266CrossRefPubMed Sasaki J, Matsumoto S, Kan H et al (2012) Objective assessment of postoperative gastrointestinal motility in elective colonic resection using a radiopaque marker provides an evidence for the abandonment of preoperative mechanical bowel preparation. J Nippon Med Sch = Nippon Ika Daigaku zasshi 79(4):259–266CrossRefPubMed
39.
go back to reference Kang BM, Lee KY, Park SJ, Lee SH (2013) Mechanical bowel preparation and prophylactic antibiotic administration in colorectal surgery: a survey of the current status in Korea. Ann Coloproctol 29(4):160–166CrossRefPubMedPubMedCentral Kang BM, Lee KY, Park SJ, Lee SH (2013) Mechanical bowel preparation and prophylactic antibiotic administration in colorectal surgery: a survey of the current status in Korea. Ann Coloproctol 29(4):160–166CrossRefPubMedPubMedCentral
40.
go back to reference Zmora O, Wexner SD, Hajjar L et al (2003) Trends in preparation for colorectal surgery: survey of the members of the American Society of Colon and Rectal Surgeons. Am Surg 69(2):150–154PubMed Zmora O, Wexner SD, Hajjar L et al (2003) Trends in preparation for colorectal surgery: survey of the members of the American Society of Colon and Rectal Surgeons. Am Surg 69(2):150–154PubMed
41.
go back to reference Slieker JC, van’t Sant HP, Vlot J, Daams F, Jansen FW, Lange JF (2011) Bowel preparation prior to laparoscopic colorectal resection: what is the current practice? J Laparoendosc Adv Surg Tech A 21(10):899–903CrossRefPubMed Slieker JC, van’t Sant HP, Vlot J, Daams F, Jansen FW, Lange JF (2011) Bowel preparation prior to laparoscopic colorectal resection: what is the current practice? J Laparoendosc Adv Surg Tech A 21(10):899–903CrossRefPubMed
42.
go back to reference Saltzman JR, Cash BD, Pasha SF et al (2015) Bowel preparation before colonoscopy. Gastrointest Endosc 81(4):781–794CrossRefPubMed Saltzman JR, Cash BD, Pasha SF et al (2015) Bowel preparation before colonoscopy. Gastrointest Endosc 81(4):781–794CrossRefPubMed
44.
go back to reference Itani KM, Wilson SE, Awad SS, Jensen EH, Finn TS, Abramson MA (2007) Polyethylene glycol versus sodium phosphate mechanical bowel preparation in elective colorectal surgery. Am J Surg 193(2):190–194CrossRefPubMed Itani KM, Wilson SE, Awad SS, Jensen EH, Finn TS, Abramson MA (2007) Polyethylene glycol versus sodium phosphate mechanical bowel preparation in elective colorectal surgery. Am J Surg 193(2):190–194CrossRefPubMed
45.
go back to reference Jung YS, Lee CK, Kim HJ, Eun CS, Han DS, Park DI (2014) Randomized controlled trial of sodium phosphate tablets vs polyethylene glycol solution for colonoscopy bowel cleansing. World J Gastroenterol : WJG 20(42):15845–15851CrossRefPubMedPubMedCentral Jung YS, Lee CK, Kim HJ, Eun CS, Han DS, Park DI (2014) Randomized controlled trial of sodium phosphate tablets vs polyethylene glycol solution for colonoscopy bowel cleansing. World J Gastroenterol : WJG 20(42):15845–15851CrossRefPubMedPubMedCentral
46.
go back to reference Kim HG, Huh KC, Koo HS et al (2015) Sodium Picosulfate with Magnesium Citrate (SPMC) Plus Laxative Is a Good Alternative to Conventional Large Volume Polyethylene Glycol in Bowel Preparation: A Multicenter Randomized Single-Blinded Trial. Gut Liver 9(4):494–501CrossRefPubMed Kim HG, Huh KC, Koo HS et al (2015) Sodium Picosulfate with Magnesium Citrate (SPMC) Plus Laxative Is a Good Alternative to Conventional Large Volume Polyethylene Glycol in Bowel Preparation: A Multicenter Randomized Single-Blinded Trial. Gut Liver 9(4):494–501CrossRefPubMed
47.
go back to reference Jeon SR, Kim HG, Lee JS et al (2015) Randomized controlled trial of low-volume bowel preparation agents for colonic bowel preparation: 2-L polyethylene glycol with ascorbic acid versus sodium picosulfate with magnesium citrate. Int J Color Dis 30(2):251–258CrossRef Jeon SR, Kim HG, Lee JS et al (2015) Randomized controlled trial of low-volume bowel preparation agents for colonic bowel preparation: 2-L polyethylene glycol with ascorbic acid versus sodium picosulfate with magnesium citrate. Int J Color Dis 30(2):251–258CrossRef
48.
go back to reference Wexner SD, Beck DE, Baron TH et al (2006) A consensus document on bowel preparation before colonoscopy: prepared by a Task Force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES). Surg Endosc 20(7):1161CrossRefPubMed Wexner SD, Beck DE, Baron TH et al (2006) A consensus document on bowel preparation before colonoscopy: prepared by a Task Force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES). Surg Endosc 20(7):1161CrossRefPubMed
49.
go back to reference Evans C, Pollock AV (1973) The reduction of surgical wound infections by prophylactic parenteral cephaloridine. A controlled clinical trial. Br J Surg 60(6):434–437CrossRefPubMed Evans C, Pollock AV (1973) The reduction of surgical wound infections by prophylactic parenteral cephaloridine. A controlled clinical trial. Br J Surg 60(6):434–437CrossRefPubMed
50.
go back to reference Polk HC Jr, Lopez-Mayor JF (1969) Postoperative wound infection: a prospective study of determinant factors and prevention. Surgery 66(1):97–103PubMed Polk HC Jr, Lopez-Mayor JF (1969) Postoperative wound infection: a prospective study of determinant factors and prevention. Surgery 66(1):97–103PubMed
51.
go back to reference Baum ML, Anish DS, Chalmers TC, Sacks HS, Smith H Jr, Fagerstrom RM (1981) A survey of clinical trials of antibiotic prophylaxis in colon surgery: evidence against further use of no-treatment controls. N Engl J Med 305(14):795–799CrossRefPubMed Baum ML, Anish DS, Chalmers TC, Sacks HS, Smith H Jr, Fagerstrom RM (1981) A survey of clinical trials of antibiotic prophylaxis in colon surgery: evidence against further use of no-treatment controls. N Engl J Med 305(14):795–799CrossRefPubMed
52.
go back to reference Song F, Glenny AM (1998) Antimicrobial prophylaxis in colorectal surgery: a systematic review of randomized controlled trials. Br J Surg 85(9):1232–1241CrossRefPubMed Song F, Glenny AM (1998) Antimicrobial prophylaxis in colorectal surgery: a systematic review of randomized controlled trials. Br J Surg 85(9):1232–1241CrossRefPubMed
53.
go back to reference Nelson RL, Glenny AM, Song F (2009) Antimicrobial prophylaxis for colorectal surgery. Cochrane Database Syst Rev (1):Cd001181 Nelson RL, Glenny AM, Song F (2009) Antimicrobial prophylaxis for colorectal surgery. Cochrane Database Syst Rev (1):Cd001181
54.
go back to reference Coppa GF, Eng K, Gouge TH, Ranson JH, Localio SA (1983) Parenteral and oral antibiotics in elective colon and rectal surgery. A prospective, randomized trial. Am J Surg 145(1):62–65CrossRefPubMed Coppa GF, Eng K, Gouge TH, Ranson JH, Localio SA (1983) Parenteral and oral antibiotics in elective colon and rectal surgery. A prospective, randomized trial. Am J Surg 145(1):62–65CrossRefPubMed
55.
go back to reference Miles AA, Miles EM, Burke J (1957) The value and duration of defence reactions of the skin to the primary lodgement of bacteria. Br J Exp Pathol 38(1):79–96PubMedPubMedCentral Miles AA, Miles EM, Burke J (1957) The value and duration of defence reactions of the skin to the primary lodgement of bacteria. Br J Exp Pathol 38(1):79–96PubMedPubMedCentral
56.
57.
go back to reference Project TJC-SCI (2014) The surgical care improvement project Project TJC-SCI (2014) The surgical care improvement project
58.
go back to reference Nichols RL, Condon RE (1971) Antibiotic preparation of the colon: failure of commonly used regimens. Surg Clin North Am 51(1):223–231PubMed Nichols RL, Condon RE (1971) Antibiotic preparation of the colon: failure of commonly used regimens. Surg Clin North Am 51(1):223–231PubMed
60.
go back to reference Cohn I Jr, Longacre AB (1957) Erythromycin and erythromycin-neomycin for intestinal antisepsis. Am J Surg 94(3):402–408CrossRefPubMed Cohn I Jr, Longacre AB (1957) Erythromycin and erythromycin-neomycin for intestinal antisepsis. Am J Surg 94(3):402–408CrossRefPubMed
61.
go back to reference Nichols RL, Broido P, Condon RE, Gorbach SL, Nyhus LM (1973) Effect of preoperative neomycin-erythromycin intestinal preparation on the incidence of infectious complications following colon surgery. Ann Surg 178(4):453–462CrossRefPubMedPubMedCentral Nichols RL, Broido P, Condon RE, Gorbach SL, Nyhus LM (1973) Effect of preoperative neomycin-erythromycin intestinal preparation on the incidence of infectious complications following colon surgery. Ann Surg 178(4):453–462CrossRefPubMedPubMedCentral
62.
go back to reference Takesue Y, Yokoyama T, Akagi S et al (2000) A brief course of colon preparation with oral antibiotics. Surg Today 30(2):112–116CrossRefPubMed Takesue Y, Yokoyama T, Akagi S et al (2000) A brief course of colon preparation with oral antibiotics. Surg Today 30(2):112–116CrossRefPubMed
63.
go back to reference Clarke JS, Condon RE, Bartlett JG, Gorbach SL, Nichols RL, Ochi S (1977) Preoperative oral antibiotics reduce septic complications of colon operations: results of prospective, randomized, double-blind clinical study. Ann Surg 186(3):251–259CrossRefPubMedPubMedCentral Clarke JS, Condon RE, Bartlett JG, Gorbach SL, Nichols RL, Ochi S (1977) Preoperative oral antibiotics reduce septic complications of colon operations: results of prospective, randomized, double-blind clinical study. Ann Surg 186(3):251–259CrossRefPubMedPubMedCentral
64.
go back to reference Moghadamyeghaneh Z, Hanna MH, Carmichael JC et al (2015) Nationwide analysis of outcomes of bowel preparation in colon surgery. J Am Coll Surg 220(5):912–920CrossRefPubMed Moghadamyeghaneh Z, Hanna MH, Carmichael JC et al (2015) Nationwide analysis of outcomes of bowel preparation in colon surgery. J Am Coll Surg 220(5):912–920CrossRefPubMed
65.
go back to reference Morris MS, Graham LA, Chu DI, Cannon JA, Hawn MT (2015) Oral Antibiotic Bowel Preparation Significantly Reduces Surgical Site Infection Rates and Readmission Rates in Elective Colorectal Surgery. Ann Surg 261(6):1034–1040CrossRefPubMed Morris MS, Graham LA, Chu DI, Cannon JA, Hawn MT (2015) Oral Antibiotic Bowel Preparation Significantly Reduces Surgical Site Infection Rates and Readmission Rates in Elective Colorectal Surgery. Ann Surg 261(6):1034–1040CrossRefPubMed
66.
go back to reference Scarborough JE, Mantyh CR, Sun Z, Migaly J (2015) Combined Mechanical and Oral Antibiotic Bowel Preparation Reduces Incisional Surgical Site Infection and Anastomotic Leak Rates After Elective Colorectal Resection: An Analysis of Colectomy-Targeted ACS NSQIP. Ann Surg 262(2):331–337CrossRefPubMed Scarborough JE, Mantyh CR, Sun Z, Migaly J (2015) Combined Mechanical and Oral Antibiotic Bowel Preparation Reduces Incisional Surgical Site Infection and Anastomotic Leak Rates After Elective Colorectal Resection: An Analysis of Colectomy-Targeted ACS NSQIP. Ann Surg 262(2):331–337CrossRefPubMed
67.
go back to reference Chen M, Song X, Chen LZ, Lin ZD, Zhang XL (2016) Comparing Mechanical Bowel Preparation With Both Oral and Systemic Antibiotics Versus Mechanical Bowel Preparation and Systemic Antibiotics Alone for the Prevention of Surgical Site Infection After Elective Colorectal Surgery: A Meta-Analysis of Randomized Controlled Clinical Trials. Dis Colon Rectum 59(1):70–78CrossRefPubMed Chen M, Song X, Chen LZ, Lin ZD, Zhang XL (2016) Comparing Mechanical Bowel Preparation With Both Oral and Systemic Antibiotics Versus Mechanical Bowel Preparation and Systemic Antibiotics Alone for the Prevention of Surgical Site Infection After Elective Colorectal Surgery: A Meta-Analysis of Randomized Controlled Clinical Trials. Dis Colon Rectum 59(1):70–78CrossRefPubMed
68.
go back to reference Rovera F, Dionigi G, Boni L et al (2006) Mechanical bowel preparation for colorectal surgery. Surg Infect 7(Suppl 2):S61–63 Rovera F, Dionigi G, Boni L et al (2006) Mechanical bowel preparation for colorectal surgery. Surg Infect 7(Suppl 2):S61–63
69.
go back to reference Murphy MM, Tevis SE, Kennedy GD (2016) Independent risk factors for prolonged postoperative ileus development. J Surg Res 201(2):279–285CrossRefPubMed Murphy MM, Tevis SE, Kennedy GD (2016) Independent risk factors for prolonged postoperative ileus development. J Surg Res 201(2):279–285CrossRefPubMed
70.
go back to reference Mahajna A, Krausz M, Rosin D et al (2005) Bowel preparation is associated with spillage of bowel contents in colorectal surgery. Dis Colon Rectum 48(8):1626–1631CrossRefPubMed Mahajna A, Krausz M, Rosin D et al (2005) Bowel preparation is associated with spillage of bowel contents in colorectal surgery. Dis Colon Rectum 48(8):1626–1631CrossRefPubMed
71.
go back to reference Zmora O, Pikarsky AJ, Wexner SD (2001) Bowel preparation for colorectal surgery. Dis Colon Rectum 44(10):1537–1549CrossRefPubMed Zmora O, Pikarsky AJ, Wexner SD (2001) Bowel preparation for colorectal surgery. Dis Colon Rectum 44(10):1537–1549CrossRefPubMed
72.
go back to reference Orias M, Mahnensmith RL, Perazella MA (1999) Extreme hyperphosphatemia and acute renal failure after a phosphorus-containing bowel regimen. Am J Nephrol 19(1):60–63CrossRefPubMed Orias M, Mahnensmith RL, Perazella MA (1999) Extreme hyperphosphatemia and acute renal failure after a phosphorus-containing bowel regimen. Am J Nephrol 19(1):60–63CrossRefPubMed
73.
go back to reference Hookey LC, Vanner S (2007) A review of current issues underlying colon cleansing before colonoscopy. Can J Gastroenterol = Journal canadien de gastroenterologie 21(2):105–111CrossRefPubMed Hookey LC, Vanner S (2007) A review of current issues underlying colon cleansing before colonoscopy. Can J Gastroenterol = Journal canadien de gastroenterologie 21(2):105–111CrossRefPubMed
74.
go back to reference Bretagnol F, Panis Y, Rullier E et al (2010) Rectal cancer surgery with or without bowel preparation: The French GRECCAR III multicenter single-blinded randomized trial. Ann Surg 252(5):863–868CrossRefPubMed Bretagnol F, Panis Y, Rullier E et al (2010) Rectal cancer surgery with or without bowel preparation: The French GRECCAR III multicenter single-blinded randomized trial. Ann Surg 252(5):863–868CrossRefPubMed
75.
go back to reference Toneva GD, Deierhoi RJ, Morris M et al (2013) Oral antibiotic bowel preparation reduces length of stay and readmissions after colorectal surgery. J Am Coll Surg 216(4):756–762, discussion 762–753CrossRefPubMed Toneva GD, Deierhoi RJ, Morris M et al (2013) Oral antibiotic bowel preparation reduces length of stay and readmissions after colorectal surgery. J Am Coll Surg 216(4):756–762, discussion 762–753CrossRefPubMed
Metadata
Title
Benefit of mechanical bowel preparation prior to elective colorectal surgery: current insights
Authors
A. C. A. Murray
R. P. Kiran
Publication date
01-08-2016
Publisher
Springer Berlin Heidelberg
Published in
Langenbeck's Archives of Surgery / Issue 5/2016
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-016-1461-9

Other articles of this Issue 5/2016

Langenbeck's Archives of Surgery 5/2016 Go to the issue