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Published in: Langenbeck's Archives of Surgery 2/2016

01-03-2016 | How-I-Do-It Article

Routes for virtually guided endoscopic liver resection of subdiaphragmatic liver tumors

Authors: Takeshi Aoki, Masahiko Murakami, Akira Fujimori, Tomotake Koizumi, Yuta Enami, Tomokazu Kusano, Kazuhiro Matsuda, Kosuke Yamada, Koji Nogaki, Yusuke Wada, Tomoki Hakozaki, Satoru Goto, Makoto Watanabe, Koji Otsuka

Published in: Langenbeck's Archives of Surgery | Issue 2/2016

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Abstract

Purpose

Laparoscopic and thoracoscopic/laparoscopic hepatectomy is a safe procedure that has potential advantages over open surgery. However, deeply positioned liver tumors require expert laparoscopic and thoracoscopic/laparoscopic hepatectomy techniques. Using simulated preoperative three-dimensional virtual endoscopy (P3DVE) guidance, we demonstrate herein that a thoracoscopic approach (TA), thoracoscopic–laparoscopic approach (TLA), and laparoscopic approach (LA) are all feasible and safe routes for performing pure laparoscopic and thoracoscopic/laparoscopic resection of liver tumors located in the 4a, 7, and 8 liver subdiaphragmatic areas.

Methods

Thirty-eight patients underwent laparoscopic and thoracoscopic/laparoscopic partial liver resection (TA 13 cases, TLA two cases, and LA 23 cases) of the subdiaphragmatic area at Showa University Hospital. All surgical approaches were preoperatively determined based on preoperative 3D virtual endoscopic simulation (P3DVES) visualization and findings using the image processing software SYNAPSE VINCENT®.

Results

Laparoscopic and thoracoscopic/laparoscopic liver resection was successfully performed for all cases under P3DVE instruction. The mean operative times using TA, TLA, and LA approaches were 193, 185, and 190 min, respectively. Mean blood loss during TA, TLA, and LA was 179, 138, and 73 g, respectively. No patients required conversion to open surgery, and there were no deaths, although there were three cases of Clavien–Dindo grade I in TA along with three cases of grade I and one case of grade II in LA.

Conclusions

TA, TLA, and LA routes performed under P3DVE instruction are feasible and safe to perform for pure laparoscopic and thoracoscopic/laparoscopic liver resection in selected patients with lesions located in the hepatic subdiaphragmatic area.
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Literature
1.
go back to reference Azagra JS, Goergen M, Gilbart E, Jacobs D (1996) Laparoscopic anatomical (hepatic) left lateral segmentectomy-technical aspects. Surg Endosc 10:758–761CrossRefPubMed Azagra JS, Goergen M, Gilbart E, Jacobs D (1996) Laparoscopic anatomical (hepatic) left lateral segmentectomy-technical aspects. Surg Endosc 10:758–761CrossRefPubMed
2.
go back to reference Kaneko H, Takagi S, Shiba T (1996) Laparoscopic partial hepatectomy and left lateral segmentectomy: technique and results of a clinical series. Surgery 120:468–475CrossRefPubMed Kaneko H, Takagi S, Shiba T (1996) Laparoscopic partial hepatectomy and left lateral segmentectomy: technique and results of a clinical series. Surgery 120:468–475CrossRefPubMed
3.
go back to reference Huscher CG, Lirici MM, Chiodini S (1998) Laparoscopic liver resections. Semin Laparosc Surg 5:204–210PubMed Huscher CG, Lirici MM, Chiodini S (1998) Laparoscopic liver resections. Semin Laparosc Surg 5:204–210PubMed
4.
go back to reference Buell JF, Cherqui D, Geller DA, O'Rourke N, Iannitti D, Dagher I, Koffron AJ, Thomas M, Gayet B, Han HS, Wakabayashi G, Belli G, Kaneko H, Ker CG, Scatton O, Laurent A, Abdalla EK, Chaudhury P, Dutson E, Gamblin C, D'Angelica M, Nagorney D, Testa G, Labow D, Manas D, Poon RT, Nelson H, Martin R, Clary B, Pinson WC, Martinie J, Vauthey JN, Goldstein R, Roayaie S, Barlet D, Espat J, Abecassis M, Rees M, Fong Y, McMasters KM, Broelsch C, Busuttil R, Belghiti J, Strasberg S, Chari RS, World Consensus Conference on Laparoscopic Surgery (2009) The international position on laparoscopic liver surgery: the Louisville statement, 2008. Ann Surg 250:825–830CrossRefPubMed Buell JF, Cherqui D, Geller DA, O'Rourke N, Iannitti D, Dagher I, Koffron AJ, Thomas M, Gayet B, Han HS, Wakabayashi G, Belli G, Kaneko H, Ker CG, Scatton O, Laurent A, Abdalla EK, Chaudhury P, Dutson E, Gamblin C, D'Angelica M, Nagorney D, Testa G, Labow D, Manas D, Poon RT, Nelson H, Martin R, Clary B, Pinson WC, Martinie J, Vauthey JN, Goldstein R, Roayaie S, Barlet D, Espat J, Abecassis M, Rees M, Fong Y, McMasters KM, Broelsch C, Busuttil R, Belghiti J, Strasberg S, Chari RS, World Consensus Conference on Laparoscopic Surgery (2009) The international position on laparoscopic liver surgery: the Louisville statement, 2008. Ann Surg 250:825–830CrossRefPubMed
5.
go back to reference Gigot JF, Glineur D, Santiago Azagra J, Goergen M, Ceuterick M, Morino M, Etienne J, Marescaux J, Mutter D, van Krunckelsven L, Descottes B, Valleix D, Lachachi F, Bertrand C, Mansvelt B, Hubens G, Saey JP, Schockmel R, Hepatobiliary and Pancreatic Section of the Royal Belgian Society of Surgery and the Belgian Group for Endoscopic Surgery (2002) Laparoscopic liver resection for malignant liver tumors: preliminary results of a multicenter European study. Ann Surg 236:90–97CrossRefPubMedPubMedCentral Gigot JF, Glineur D, Santiago Azagra J, Goergen M, Ceuterick M, Morino M, Etienne J, Marescaux J, Mutter D, van Krunckelsven L, Descottes B, Valleix D, Lachachi F, Bertrand C, Mansvelt B, Hubens G, Saey JP, Schockmel R, Hepatobiliary and Pancreatic Section of the Royal Belgian Society of Surgery and the Belgian Group for Endoscopic Surgery (2002) Laparoscopic liver resection for malignant liver tumors: preliminary results of a multicenter European study. Ann Surg 236:90–97CrossRefPubMedPubMedCentral
6.
go back to reference Otsuka Y, Tsuchiya M, Maeda T, Katagiri T, Isii J, Tamura A, Yamazaki K, Kubota Y, Suzuki T, Suzuki T, Kagami S, Kaneko H (2009) Laparoscopic hepatectomy for liver tumors: proposals for standardization. J Hepato-Biliary-Pancreat Surg 16:720–725CrossRef Otsuka Y, Tsuchiya M, Maeda T, Katagiri T, Isii J, Tamura A, Yamazaki K, Kubota Y, Suzuki T, Suzuki T, Kagami S, Kaneko H (2009) Laparoscopic hepatectomy for liver tumors: proposals for standardization. J Hepato-Biliary-Pancreat Surg 16:720–725CrossRef
7.
go back to reference Kazaryan AM, Røsok BI, Marangos IP, Rosseland AR, Edwin B (2011) Comparative evaluation of laparoscopic liver resection for posterosuperior and anterolateral segments. Surg Endosc 25:3881–3889CrossRefPubMedPubMedCentral Kazaryan AM, Røsok BI, Marangos IP, Rosseland AR, Edwin B (2011) Comparative evaluation of laparoscopic liver resection for posterosuperior and anterolateral segments. Surg Endosc 25:3881–3889CrossRefPubMedPubMedCentral
8.
go back to reference Cho JY, Han HS, Yoon YS, Shin SH (2008) Feasibility of laparoscopic liver resection for tumors located in the posterosuperior segments of the liver, with a special reference to overcoming current limitations on tumor location. Surgery 144:32–38CrossRefPubMed Cho JY, Han HS, Yoon YS, Shin SH (2008) Feasibility of laparoscopic liver resection for tumors located in the posterosuperior segments of the liver, with a special reference to overcoming current limitations on tumor location. Surgery 144:32–38CrossRefPubMed
9.
go back to reference Yoon YS, Han HS, Cho JY, Ahn KS (2010) Total laparoscopic liver resection for hepatocellular carcinoma located in all segments of the liver. Surg Endosc 24:1630–1637CrossRefPubMed Yoon YS, Han HS, Cho JY, Ahn KS (2010) Total laparoscopic liver resection for hepatocellular carcinoma located in all segments of the liver. Surg Endosc 24:1630–1637CrossRefPubMed
10.
go back to reference Cho JY, Han HS, Yoon YS, Shin SH (2008) Experiences of laparoscopic liver resection including lesions in the posterosuperior segments of the liver. Surg Endosc 22:2344–2349CrossRefPubMed Cho JY, Han HS, Yoon YS, Shin SH (2008) Experiences of laparoscopic liver resection including lesions in the posterosuperior segments of the liver. Surg Endosc 22:2344–2349CrossRefPubMed
11.
go back to reference Ikeda T, Toshima T, Harimoto N, Yamashita Y, Ikegami T, Yoshizumi T, Soejima Y, Shirabe K, Maehara Y (2014) Laparoscopic liver resection in the semiprone position for tumors in the anterosuperior and posterior segments, using a novel dual-handling technique and bipolar irrigation system. Surg Endosc 28:2484–2492CrossRefPubMedPubMedCentral Ikeda T, Toshima T, Harimoto N, Yamashita Y, Ikegami T, Yoshizumi T, Soejima Y, Shirabe K, Maehara Y (2014) Laparoscopic liver resection in the semiprone position for tumors in the anterosuperior and posterior segments, using a novel dual-handling technique and bipolar irrigation system. Surg Endosc 28:2484–2492CrossRefPubMedPubMedCentral
12.
go back to reference Ishizawa T, Gumbs AA, Kokudo N, Gayet B (2012) Laparoscopic segmentectomy of the liver: from segment I to VIII. Ann Surg 256:959–964CrossRefPubMed Ishizawa T, Gumbs AA, Kokudo N, Gayet B (2012) Laparoscopic segmentectomy of the liver: from segment I to VIII. Ann Surg 256:959–964CrossRefPubMed
13.
go back to reference Okuda Y, Honda G, Kurata M, Kobayashi S, Sakamoto K, Takahashi K (2015) A safe and valid procedure for pure laparoscopic partial hepatectomy of the most posterosuperior area: the top of segment 7. J Am Coll Surg 220:e17–e21CrossRefPubMed Okuda Y, Honda G, Kurata M, Kobayashi S, Sakamoto K, Takahashi K (2015) A safe and valid procedure for pure laparoscopic partial hepatectomy of the most posterosuperior area: the top of segment 7. J Am Coll Surg 220:e17–e21CrossRefPubMed
14.
go back to reference Murakami M, Aoki T, Kato T (2011) Video-assisted thoracoscopic surgery: hepatectomy for liver neoplasm. World J Surg 35:1050–1054CrossRefPubMed Murakami M, Aoki T, Kato T (2011) Video-assisted thoracoscopic surgery: hepatectomy for liver neoplasm. World J Surg 35:1050–1054CrossRefPubMed
15.
go back to reference Mise Y, Tani K, Aoki T, Sakamoto Y, Hasegawa K, Sugawara Y, Kokudo N (2013) Virtual liver resection: computer-assisted operation planning using a three-dimensional liver representation. J Hepatobiliary Pancreat Sci 20:157–164CrossRefPubMed Mise Y, Tani K, Aoki T, Sakamoto Y, Hasegawa K, Sugawara Y, Kokudo N (2013) Virtual liver resection: computer-assisted operation planning using a three-dimensional liver representation. J Hepatobiliary Pancreat Sci 20:157–164CrossRefPubMed
16.
go back to reference Ohshima S (2014) Volume analyzer SYNAPSE VINCENT for liver analysis. J Hepatobiliary Pancreat Sci 21:235–238CrossRefPubMed Ohshima S (2014) Volume analyzer SYNAPSE VINCENT for liver analysis. J Hepatobiliary Pancreat Sci 21:235–238CrossRefPubMed
17.
go back to reference Lamadé W, Glombitza G, Fischer L, Chiu P, Cárdenas CE Sr, Thorn M, Meinzer HP, Grenacher L, Bauer H, Lehnert T, Herfarth C (2000) The impact of 3-dimensional reconstructions on operation planning in liver surgery. Arch Surg 135:1256–1261CrossRefPubMed Lamadé W, Glombitza G, Fischer L, Chiu P, Cárdenas CE Sr, Thorn M, Meinzer HP, Grenacher L, Bauer H, Lehnert T, Herfarth C (2000) The impact of 3-dimensional reconstructions on operation planning in liver surgery. Arch Surg 135:1256–1261CrossRefPubMed
18.
go back to reference Marescaux J, Clément JM, Tassetti V, Koehl C, Cotin S, Russier Y, Mutter D, Delingette H, Ayache N (1998) Virtual reality applied to hepatic surgery simulation: the next revolution. Ann Surg 228:627–634CrossRefPubMedPubMedCentral Marescaux J, Clément JM, Tassetti V, Koehl C, Cotin S, Russier Y, Mutter D, Delingette H, Ayache N (1998) Virtual reality applied to hepatic surgery simulation: the next revolution. Ann Surg 228:627–634CrossRefPubMedPubMedCentral
19.
go back to reference Saito S, Yamanaka J, Miura K, Nakao N, Nagao T, Sugimoto T, Hirano T, Kuroda N, Iimuro Y, Fujimoto J (2005) A novel 3D hepatectomy simulation based on liver circulation: application to liver resection and transplantation. Hepatology 41:1297–1304CrossRefPubMed Saito S, Yamanaka J, Miura K, Nakao N, Nagao T, Sugimoto T, Hirano T, Kuroda N, Iimuro Y, Fujimoto J (2005) A novel 3D hepatectomy simulation based on liver circulation: application to liver resection and transplantation. Hepatology 41:1297–1304CrossRefPubMed
20.
go back to reference Satou S, Sugawara Y, Matsui Y, Kaneko J, Kishi Y, Imamura H, Kokudo N, Makuuchi M (2006) Preoperative estimation of right lateral sector graft by three-dimensional computed tomography. Transplant Proc 38:1400–1403CrossRefPubMed Satou S, Sugawara Y, Matsui Y, Kaneko J, Kishi Y, Imamura H, Kokudo N, Makuuchi M (2006) Preoperative estimation of right lateral sector graft by three-dimensional computed tomography. Transplant Proc 38:1400–1403CrossRefPubMed
21.
go back to reference Yamanaka J, Saito S, Fujimoto J (2007) Impact of preoperative planning using virtual segmental volumetry on liver resection for hepatocellular carcinoma. World J Surg 31:1249–1255CrossRefPubMed Yamanaka J, Saito S, Fujimoto J (2007) Impact of preoperative planning using virtual segmental volumetry on liver resection for hepatocellular carcinoma. World J Surg 31:1249–1255CrossRefPubMed
22.
go back to reference Lang H, Radtke A, Hindennach M, Schroeder T, Frühauf NR, Malagó M, Bourquain H, Peitgen HO, Oldhafer KJ, Broelsch CE (2005) Impact of virtual tumor resection and computer-assisted risk analysis on operation planning and intraoperative strategy in major hepatic resection. Arch Surg 140:629–638CrossRefPubMed Lang H, Radtke A, Hindennach M, Schroeder T, Frühauf NR, Malagó M, Bourquain H, Peitgen HO, Oldhafer KJ, Broelsch CE (2005) Impact of virtual tumor resection and computer-assisted risk analysis on operation planning and intraoperative strategy in major hepatic resection. Arch Surg 140:629–638CrossRefPubMed
23.
go back to reference Makuuchi M, Kosuge T, Takayama T, Yamazaki S, Kakazu T, Miyagawa S, Kawasaki S (1993) Surgery for small liver cancers. Semin Surg Oncol 9:298–304CrossRefPubMed Makuuchi M, Kosuge T, Takayama T, Yamazaki S, Kakazu T, Miyagawa S, Kawasaki S (1993) Surgery for small liver cancers. Semin Surg Oncol 9:298–304CrossRefPubMed
24.
go back to reference Okamura Y, Takeda S, Fujii T, Sugimoto H, Nomoto S, Nakao A (2011) Impact of the thoracoabdominal approach on peri- and postoperative outcomes of hepatectomy for hepatocellular carcinoma. World J Surg 35:1042–1049CrossRefPubMed Okamura Y, Takeda S, Fujii T, Sugimoto H, Nomoto S, Nakao A (2011) Impact of the thoracoabdominal approach on peri- and postoperative outcomes of hepatectomy for hepatocellular carcinoma. World J Surg 35:1042–1049CrossRefPubMed
25.
go back to reference Xia F, Poon RT, Fan ST, Wong J (2003) Thoracoabdominal approach for right-sided hepatic resection for hepatocellular carcinoma. J Am Coll Surg 196:418–427CrossRefPubMed Xia F, Poon RT, Fan ST, Wong J (2003) Thoracoabdominal approach for right-sided hepatic resection for hepatocellular carcinoma. J Am Coll Surg 196:418–427CrossRefPubMed
26.
go back to reference Smyrniotis V, Arkadopoulos N, Theodosopoulos T, Theodoraki K, Dafnios N, Kannas D, Dimakakos P (2007) Transdiaphragmatic approach facilitates resection of large (>12 cm) liver tumors. J Hepato-Biliary-Pancreat Surg 14:383–386CrossRef Smyrniotis V, Arkadopoulos N, Theodosopoulos T, Theodoraki K, Dafnios N, Kannas D, Dimakakos P (2007) Transdiaphragmatic approach facilitates resection of large (>12 cm) liver tumors. J Hepato-Biliary-Pancreat Surg 14:383–386CrossRef
27.
go back to reference Lamadé W, Vetter M, Hassenpflug P, Thorn M, Meinzer HP, Herfarth C (2002) Navigation and image-guided HBP surgery: a review and preview. J Hepato-Biliary-Pancreat Surg 9:592–599CrossRef Lamadé W, Vetter M, Hassenpflug P, Thorn M, Meinzer HP, Herfarth C (2002) Navigation and image-guided HBP surgery: a review and preview. J Hepato-Biliary-Pancreat Surg 9:592–599CrossRef
28.
go back to reference Golse N, Ducerf C, Rode A, Gouillat C, Baulieux J, Mabrut JY (2012) Transthoracic approach for liver tumors. J Visc Surg 149:e11–e22CrossRefPubMed Golse N, Ducerf C, Rode A, Gouillat C, Baulieux J, Mabrut JY (2012) Transthoracic approach for liver tumors. J Visc Surg 149:e11–e22CrossRefPubMed
Metadata
Title
Routes for virtually guided endoscopic liver resection of subdiaphragmatic liver tumors
Authors
Takeshi Aoki
Masahiko Murakami
Akira Fujimori
Tomotake Koizumi
Yuta Enami
Tomokazu Kusano
Kazuhiro Matsuda
Kosuke Yamada
Koji Nogaki
Yusuke Wada
Tomoki Hakozaki
Satoru Goto
Makoto Watanabe
Koji Otsuka
Publication date
01-03-2016
Publisher
Springer Berlin Heidelberg
Published in
Langenbeck's Archives of Surgery / Issue 2/2016
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-016-1385-4

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