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Langenbeck's Archives of Surgery
Published in: Langenbeck's Archives of Surgery 8/2014

01-12-2014 | Original Article

Surgical strategy for primary hyperparathyreoidism with thyroid hemiagenesis

Authors: Cesare Carlo Ferrari, Kerstin Lorenz, Gianlorenzo Dionigi, Henning Dralle

Published in: Langenbeck's Archives of Surgery | Issue 8/2014

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Abstract

Background

Thyroid hemiagenesis is a rare congenital anomaly, and still more rarely associated with primary hyperparathyroidism (pHPT). Due to the embryologic pathways of the thyroid and parathyroid glands, it remains unclear whether or not thyroid hemiagenesis may be linked to ipsilateral parathyroid agenesis, and consequently, surgical strategy for thyroid hemiagenesis associated pHPT (THAP) does not only depend on preoperative localization but also on the thyroid anomaly.

Methods

Including the present case report, a total of nine cases with THAP retrieved from the literature were reviewed. Seven of nine cases had thyroid hemiagenesis on the left side, three out of nine showed a parathyroid adenoma on the contralateral side to the thyroid hemiagenesis.

Conclusions

Based on these cases, it can be concluded that the embryologic pathways of the thyroid and parathyroid glands are different, and in cases of THAP, parathyroid exploration should follow standard recommendations for pHPT surgery.
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Metadata
Title
Surgical strategy for primary hyperparathyreoidism with thyroid hemiagenesis
Authors
Cesare Carlo Ferrari
Kerstin Lorenz
Gianlorenzo Dionigi
Henning Dralle
Publication date
01-12-2014
Publisher
Springer Berlin Heidelberg
Published in
Langenbeck's Archives of Surgery / Issue 8/2014
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-014-1228-0

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