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Langenbeck's Archives of Surgery

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01-03-2008 | Original Article

Validity of observation interval for synchronous hepatic metastases of colorectal cancer: changes in hepatic and extrahepatic metastatic foci

Authors: Yasuhiro Shimizu, Kenzo Yasui, Tsuyoshi Sano, Takashi Hirai, Yukihide Kanemitsu, Koji Komori, Tomoyuki Kato

Published in: Langenbeck's Archives of Surgery | Issue 2/2008

Abstract

Background

In cases of synchronous colorectal hepatic metastases, the primary colorectal cancer maintains a strong influence on the metastases, so the possibility of occult hepatic and extrahepatic metastases must be kept in mind. Our treatment policy has been to reevaluate the metastases at an interval of 3 months after colorectal resection and determine treatment strategy. We examined the validity of observation interval for synchronous hepatic metastases.

Materials and methods

The treatment course was investigated for 36 patients with no extrahepatic lesion remnants at colorectal surgery and a simultaneously resectable liver (H1 group).

Results

In the H1 group, eight patients underwent simultaneous colorectal and hepatic resections, while the treatment course for 28 patients was decided after an interval. Hepatic resection was not indicated in nine of the 28 patients during the interval. New lesions appeared during the interval in seven of 19 interval hepatic resection patients. In 16 (57%) of 28 interval patients, there was a change in the hepatic resection procedure or surgical indications.

Conclusion

Reevaluation after an observation interval allows accurate understanding of the number and location of hepatic metastases and is beneficial in determining candidates for surgery and in selecting treatment plan.

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Title: Validity of observation interval for synchronous hepatic metastases of colorectal cancer: changes in hepatic and extrahepatic metastatic foci
Authors: Yasuhiro Shimizu
Kenzo Yasui
Tsuyoshi Sano
Takashi Hirai
Yukihide Kanemitsu
Koji Komori
Tomoyuki Kato
Publication date: 01-03-2008
Publisher: Springer-Verlag
Published in: Langenbeck's Archives of Surgery / Issue 2/2008
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI: https://doi.org/10.1007/s00423-007-0258-2

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Validity of observation interval for synchronous hepatic metastases of colorectal cancer: changes in hepatic and extrahepatic metastatic foci

Abstract

Background

Materials and methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Materials and methods

Results

Conclusion

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