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European Journal of Applied Physiology

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Open Access 01-01-2019 | Original Article

Changes of blood pressure following initiation of physical inactivity and after external addition of pulses to circulation

Authors: Marvin A. Sackner, Shivam Patel, Jose A. Adams

Published in: European Journal of Applied Physiology | Issue 1/2019

Abstract

Purpose

To determine whether an innovative, motorized, wellness device that effortlessly produces physical activity (JD) can mitigate the hypertensive effects of prolonged sitting or lying down.

Methods

Twenty-two normotensive and hypertensive adults of both genders gave informed consent to participate in a randomized controlled crossover study of a passive simulated jogging device (JD) in both supine and seated postures. Each study participant was monitored with a continuous non-invasive arterial pressure monitoring device (CNAP) over 60 min. The initial 10 min served as baseline for each posture. The subjects were randomized to begin with either JD or SHAM control for 30 min, and monitoring was continued for an additional 10 min in one posture; three days later posture and order of JD or SHAM were changed.

Results

In both seated and supine postures, SHAM was associated with a significant rise in blood pressure (BP) which was observed within 5–10 min; it continued to rise or remain elevated for over a 40-min observation period. In contrast, JD produced a significant decrease in both systolic and diastolic blood pressure in both postures. During recovery in seated posture JD decreased systolic and diastolic BP by − 8.1 and − 7.6 mmHg, respectively. In supine posture, a similar decrease in BP occurred.

Conclusions

There is rapid onset of increase in systolic and diastolic BP with physical inactivity in both supine and seated postures. Administration of JD significantly decreased BP in both postures. Further studies are needed to assess long-term effectiveness.

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Title: Changes of blood pressure following initiation of physical inactivity and after external addition of pulses to circulation
Authors: Marvin A. Sackner
Shivam Patel
Jose A. Adams
Publication date: 01-01-2019
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Applied Physiology / Issue 1/2019
Print ISSN: 1439-6319
Electronic ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-018-4016-7

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Changes of blood pressure following initiation of physical inactivity and after external addition of pulses to circulation

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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