Top

Published in:

01-11-2015 | Original Article

Obesity-related differences in neuromuscular fatigue in adolescent girls

Authors: Sebastian Garcia-Vicencio, Vincent Martin, Virginie Kluka, Charlotte Cardenoux, Anne-Gaëlle Jegu, Anne-Véronique Fourot, Emmanuel Coudeyre, Sébastien Ratel

Published in: European Journal of Applied Physiology | Issue 11/2015

Abstract

Purpose

The aim of this study was to investigate the effect of obesity on neuromuscular fatigue in adolescent girls.

Methods

Twelve lean (13.6 ± 0.8 years) and 12 obese (13.9 ± 0.9 years) girls repeated 5-s maximal voluntary contractions (MVC) of the knee extensors until the generated torque reached 55 % of its initial value. Magnetic stimulations were delivered to the femoral nerve every five MVCs to follow the course of voluntary activation (VA) and potentiated twitch torque (Qtw_pot).

Results

Torque reached 55 % of its initial value after 52.6 ± 20.4 and 74.9 ± 22.8 repetitions in obese and lean girls, respectively (p < 0.01). Furthermore, the decline of VA was smaller in obese girls (p < 0.001). In contrast, Qtw_pot decreased to a greater extent in obese girls (p < 0.05).

Conclusions

Obese girls fatigue faster than their lean counterparts. The peripheral factors mainly account for fatigue in obese girls, whereas central factors are mainly involved in lean girls.

Abdelmoula A, Martin V, Bouchant A, Walrand S, Lavet C, Taillardat M, Maffiuletti NA, Boisseau N, Duche P, Ratel S (2012) Knee extension strength in obese and nonobese male adolescents. Appl Physiol Nutr Metab 37(2):269–275. doi:10.1139/h2012-010 CrossRefPubMed

Bogdanis GC (2012) Effects of physical activity and inactivity on muscle fatigue. Front Physiol 3:142. doi:10.3389/fphys.2012.00142 PubMedCentralCrossRefPubMed

Bogdanis GC, Nevill ME, Boobis LH, Lakomy HK (1996) Contribution of phosphocreatine and aerobic metabolism to energy supply during repeated sprint exercise. J Appl Physiol 80(3):876–884PubMed

Callahan DM, Foulis SA, Kent-Braun JA (2009) Age-related fatigue resistance in the knee extensor muscles is specific to contraction mode. Muscle Nerve 39(5):692–702. doi:10.1002/mus.21278 PubMedCentralCrossRefPubMed

Cavuoto LA, Nussbaum MA (2013) Obesity-related differences in muscular capacity during sustained isometric exertions. Appl Ergon 44(2):254–260. doi:10.1016/j.apergo.2012.07.011 CrossRefPubMed

Cavuoto LA, Nussbaum MA (2014) The influences of obesity and age on functional performance during intermittent upper extremity tasks. J Occup Environ Hyg 11(9):583–590. doi:10.1080/15459624.2014.887848 CrossRefPubMed

Cole TJ, Bellizzi MC, Flegal KM, Dietz WH (2000) Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 320(7244):1240–1243PubMedCentralCrossRefPubMed

Enoka RM, Stuart DG (1992) Neurobiology of muscle fatigue. J Appl Physiol 72(5):1631–1648PubMed

Fleischman A, Kron M, Systrom DM, Hrovat M, Grinspoon SK (2009) Mitochondrial function and insulin resistance in overweight and normal weight children. J Clin Endocrinol Metab 94(12):4923–4930. doi:10.1210/jc.2009-1590 PubMedCentralCrossRefPubMed

Gandevia SC (2001) Spinal and supraspinal factors in human muscle fatigue. Physiol Rev 81(4):1725–1789PubMed

Halvatsiotis P, Short KR, Bigelow M, Nair KS (2002) Synthesis rate of muscle proteins, muscle functions, and amino acid kinetics in type 2 diabetes. Diabetes 51(8):2395–2404CrossRefPubMed

Hamada T, Sale DG, MacDougall JD, Tarnopolsky MA (2003) Interaction of fibre type, potentiation and fatigue in human knee extensor muscles. Acta Physiol Scand 178(2):165–173. doi:10.1046/j.1365-201X.2003.01121.x CrossRefPubMed

Hermens HJ, Freriks B, Disselhorst-Klug C, Rau G (2000) Development of recommendations for SEMG sensors and sensor placement procedures. J Electromyogr Kinesiol 10(5):361–374CrossRefPubMed

Hunter SK, Critchlow A, Shin IS, Enoka RM (2004) Fatigability of the elbow flexor muscles for a sustained submaximal contraction is similar in men and women matched for strength. J Appl Physiol 96(1):195–202. doi:10.1152/japplphysiol.00893.2003 CrossRefPubMed

Kalmar JM, Cafarelli E (1999) Effects of caffeine on neuromuscular function. J Appl Physiol 87(2):801–808PubMed

Kent-Braun JA (1999) Central and peripheral contributions to muscle fatigue in humans during sustained maximal effort. Eur J Appl Physiol 80(1):57–63. doi:10.1007/s004210050558 CrossRef

Kent-Braun JA, Ng AV, Doyle JW, Towse TF (2002) Human skeletal muscle responses vary with age and gender during fatigue due to incremental isometric exercise. J Appl Physiol 93(5):1813–1823. doi:10.1152/japplphysiol.00091.2002 CrossRefPubMed

Kluka V, Martin V, Vicencio SG, Jegu AG, Cardenoux C, Morio C, Coudeyre E, Ratel S (2015) Effect of muscle length on voluntary activation level in children and adults. Med Sci Sports Exerc 47(4):718–724. doi:10.1249/MSS.0000000000000463 CrossRefPubMed

Kriketos AD, Baur LA, O’Connor J, Carey D, King S, Caterson ID, Storlien LH (1997) Muscle fibre type composition in infant and adult populations and relationships with obesity. Int J Obes Relat Metab Disord 21(9):796–801CrossRefPubMed

Maffiuletti NA, Jubeau M, Munzinger U, Bizzini M, Agosti F, De Col A, Lafortuna CL, Sartorio A (2007) Differences in quadriceps muscle strength and fatigue between lean and obese subjects. Eur J Appl Physiol 101(1):51–59. doi:10.1007/s00421-007-0471-2 CrossRefPubMed

Maffiuletti NA, Jubeau M, Agosti F, De Col A, Sartorio A (2008) Quadriceps muscle function characteristics in severely obese and nonobese adolescents. Eur J Appl Physiol 103(4):481–484. doi:10.1007/s00421-008-0737-3 CrossRefPubMed

Maffiuletti NA, Ratel S, Sartorio A, Martin V (2013) The impact of obesity on in vivo human skeletal muscle function. Curr Obes Rep 2:251–260CrossRef

Martin V, Kerherve H, Messonnier LA, Banfi JC, Geyssant A, Bonnefoy R, Feasson L, Millet GY (2010) Central and peripheral contributions to neuromuscular fatigue induced by a 24-h treadmill run. J Appl Physiol 108(5):1224–1233. doi:10.1152/japplphysiol.01202.2009 CrossRefPubMed

Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28(7):412–419CrossRefPubMed

Mehta RK, Cavuoto LA (2015) The effects of obesity, age, and relative workload levels on handgrip endurance. Appl Ergon 46:91–5. doi:10.1016/j.apergo.2014.07.007 (Part A)

Merton PA (1954) Voluntary strength and fatigue. J Physiol 123(3):553–564

Minetto MA, Botter A, Sprager S, Agosti F, Patrizi A, Lanfranco F, Sartorio A (2013) Feasibility study of detecting surface electromyograms in severely obese patients. J Electromyogr Kinesiol 23(2):285–295. doi:10.1016/j.jelekin.2012.09.008 CrossRefPubMed

Mirwald RL, Baxter-Jones AD, Bailey DA, Beunen GP (2002) An assessment of maturity from anthropometric measurements. Med Sci Sports Exerc 34(4):689–694CrossRefPubMed

Paolillo FR, Milan JC, Bueno Pde G, Paolillo AR, Borghi-Silva A, Parizotto NA, Arena R, Kurachi C, Bagnato VS (2012) Effects of excess body mass on strength and fatigability of quadriceps in postmenopausal women. Menopause 19(5):556–561. doi:10.1097/gme.0b013e3182364e80 CrossRefPubMed

Ratel S, Duche P, Hennegrave A, Van Praagh E, Bedu M (2002) Acid-base balance during repeated cycling sprints in boys and men. J Appl Physiol 92(2):479–485. doi:10.1152/japplphysiol.00495.2001 CrossRefPubMed

Ratel S, Kluka V, Garcia-Vicencio S, Jegu AG, Cardenoux C, Morio C, Coudeyre E, Martin V (2015) Insights into the mechanisms of neuromuscular fatigue in boys and men. Med Sci Sports Exerc May 12. (Epub ahead of print)

Russ D (2009) Sex differences in muscle fatigue. In: Williams CA, Ratel S (eds) Human muscle fatigue. Routledge, London and New-York, pp 135–163

Slattery MJ, Bredella MA, Thakur H, Torriani M, Misra M (2014) Insulin resistance and impaired mitochondrial function in obese adolescent girls. Metab Syndr Relat Disord 12(1):56–61. doi:10.1089/met.2013.0100 PubMedCentralCrossRefPubMed

Tanner JM, Whitehouse RH (1976) Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. Arch Dis Child 51(3):170–179PubMedCentralCrossRefPubMed

Tessier S, Vuillemin A, Briançon S (2007) Psychometric properties of a physical activity questionnaire for school children aged between 6 and 10 years: QAPE-week. Sci Sport 22(7):224–231CrossRef

Tsiros MD, Coates AM, Howe PR, Grimshaw PN, Buckley JD (2011) Obesity: the new childhood disability? Obes Rev 12(1):26–36. doi:10.1111/j.1467-789X.2009.00706.x CrossRefPubMed

Tsiros MD, Coates AM, Howe PR, Grimshaw PN, Walkley J, Shield A, Mallows R, Hills AP, Kagawa M, Shultz S, Buckley JD (2013) Knee extensor strength differences in obese and healthy-weight 10-to 13-year-olds. Eur J Appl Physiol 113(6):1415–1422. doi:10.1007/s00421-012-2561-z CrossRefPubMed

Vukovic R, Mitrovic K, Milenkovic T, Todorovic S, Soldatovic I, Sipetic-Grujicic S, Zdravkovic D (2013) Insulin-sensitive obese children display a favorable metabolic profile. Eur J Pediatr 172(2):201–206. doi:10.1007/s00431-012-1867-5 CrossRefPubMed

Wade AJ, Marbut MM, Round JM (1990) Muscle fibre type and aetiology of obesity. Lancet 335(8693):805–808CrossRefPubMed

Wigmore DM, Propert K, Kent-Braun JA (2006) Blood flow does not limit skeletal muscle force production during incremental isometric contractions. Eur J Appl Physiol 96(4):370–378. doi:10.1007/s00421-005-0037-0 CrossRefPubMed

Yan AF, Voorhees CC, Beck KH, Wang MQ (2014) A social ecological assessment of physical activity among urban adolescents. Am J Health Behav 38(3):379–391. doi:10.5993/AJHB.38.3.7 CrossRefPubMed

Zafeiridis A, Dalamitros A, Dipla K, Manou V, Galanis N, Kellis S (2005) Recovery during high-intensity intermittent anaerobic exercise in boys, teens, and men. Med Sci Sports Exerc 37(3):505–512CrossRefPubMed

Title: Obesity-related differences in neuromuscular fatigue in adolescent girls
Authors: Sebastian Garcia-Vicencio
Vincent Martin
Virginie Kluka
Charlotte Cardenoux
Anne-Gaëlle Jegu
Anne-Véronique Fourot
Emmanuel Coudeyre
Sébastien Ratel
Publication date: 01-11-2015
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Applied Physiology / Issue 11/2015
Print ISSN: 1439-6319
Electronic ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-015-3222-9

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Obesity-related differences in neuromuscular fatigue in adolescent girls

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

Please log in to get access to this content

Other articles of this Issue 11/2015

Acute response to cluster sets in trained and untrained men

Hot water immersion induces an acute cytokine response in cervical spinal cord injury

Haemodynamics of aerobic and resistance blood flow restriction exercise in young and older adults

Release of bulk cell free DNA during physical exercise occurs independent of extracellular vesicles

Effect of 3-week high-intensity interval training on VO2max, total haemoglobin mass, plasma and blood volume in well-trained athletes

Estimating the tendency of motor unit recruitment during steady-hold and rapid contractions using surface EMG and Turns-amplitude analysis