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01-08-2011 | Short Communication

Strong ion reserve: a viewpoint on acid base equilibria and buffering

Author: Michalis Agrafiotis

Published in: European Journal of Applied Physiology | Issue 8/2011

Abstract

Evidence suggests that strong ions can exist reversibly bound to proteins in a pH-dependent manner and that they can be recruited into the biological solution, modulating its strong ion difference in a process that opposes the acid base disturbances imposed on the system. These recruitable strong ions represent the solution’s “strong ions”. The physiological role of these protein-bound strong ion reserve in the buffering of acid base disorders is discussed.

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Title: Strong ion reserve: a viewpoint on acid base equilibria and buffering
Author: Michalis Agrafiotis
Publication date: 01-08-2011
Publisher: Springer-Verlag
Published in: European Journal of Applied Physiology / Issue 8/2011
Print ISSN: 1439-6319
Electronic ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-010-1803-1

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