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Open Access 01-11-2009 | Original Article

Effect of local cold-pack application on systemic anabolic and inflammatory response to sprint-interval training: a prospective comparative trial

Authors: Dan Nemet, Yoav Meckel, Sheli Bar-Sela, Frank Zaldivar, Dan M. Cooper, Alon Eliakim

Published in: European Journal of Applied Physiology | Issue 4/2009

Abstract

We evaluated the effect of cold ice-pack application following a brief sprint-interval training on the balance between anabolic mediators [growth hormone (GH), insulin-like growth factor-I (IGF-I), testosterone], catabolic markers (cortisol, IGFBP-1), and circulating pro [Interlukin-6 (IL-6) and IL-1β]- and anti-inflammatory cytokines [IL-1 receptor antagonist (IL-1ra)]. Twelve males, elite junior handball players performed 4 × 250 m treadmill run, at 80% of each individual’s maximal speed, followed by a rest period with and without local cold-pack application. Pre, immediately post, and 60-min post-exercise blood samples were drawn. Exercise was associated with a significant increase in IL-6, GH, IGFBP-3, and testosterone levels. Local cold-pack application was associated with significant decreases in IL-1β, IL-1ra, IGF-I, and IGFBP-3 and a greater increase of IGFBP-1 during recovery. Local ice therapy immediately following sprint-interval training was associated with greater decreases in both pro- and anti-inflammatory cytokines and anabolic hormones supporting some clinical evidence for possible negative effects on athletic performance.

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Title: Effect of local cold-pack application on systemic anabolic and inflammatory response to sprint-interval training: a prospective comparative trial
Authors: Dan Nemet
Yoav Meckel
Sheli Bar-Sela
Frank Zaldivar
Dan M. Cooper
Alon Eliakim
Publication date: 01-11-2009
Publisher: Springer-Verlag
Published in: European Journal of Applied Physiology / Issue 4/2009
Print ISSN: 1439-6319
Electronic ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-009-1138-y

At a glance: The STEP trials

Springer Medicine

Effect of local cold-pack application on systemic anabolic and inflammatory response to sprint-interval training: a prospective comparative trial

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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