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Published in: Graefe's Archive for Clinical and Experimental Ophthalmology 12/2019

01-12-2019 | Angiography | Glaucoma

Optic nerve head microvascular changes after phacoemulsification surgery

Authors: Müjdat Karabulut, Sinem Karabulut, Sabahattin Sül, Aylin Karalezli

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 12/2019

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Abstract

Background

To determine optic nerve head (ONH) microvascular changes detected by optical coherence tomography angiography (OCTA) and intraocular pressure changes (IOPs) after uncomplicated phacoemulsification surgery.

Methods

The study was designed as a prospective observational study. Twenty-four eyes were included. Eyes with retinal vascular pathology, any type of age-related macular degeneration, IOP more than 21 mmHg, axial length less than 20 mm and more than 24 mm, corneal edema and cataracts that can disrupt images, and history of ocular surgery were excluded. Patients underwent OCTA imaging and IOP measurement preoperatively (baseline) and postoperatively (weeks 1 and 4). Vessel density % (VD) in the total disc, peripapillary, and inside disc were measured. IOP was measured with the applanation tonometer. Comparison of VD and IOP and correlation between VD and İOP change were determined.

Results

VD was significantly increased in all quadrants in week 4 compared to those in week 1. In terms of VD and IOP, although there was no significant difference between week 1 and baseline, week 4 results were significantly different from baseline (p < 0.05 and p < 0.001, respectively). The IOP was significantly lower in week 4 (14.8 mmHg) than in week 1 (16.0 mmHg) (p < 0.001). There was a significant negative correlation between the inside disc and total VD and IOP at weeks 1 and 4.

Conclusion

Phacoemulsification surgery can result in a decrease in IOP and an increase in VD of the ONH.
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Metadata
Title
Optic nerve head microvascular changes after phacoemulsification surgery
Authors
Müjdat Karabulut
Sinem Karabulut
Sabahattin Sül
Aylin Karalezli
Publication date
01-12-2019
Publisher
Springer Berlin Heidelberg
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 12/2019
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-019-04473-1

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