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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-02-2017 | Retinal Disorders

Retinal sensitivity after selective retina therapy (SRT) on patients with central serous chorioretinopathy

Authors: Ayako Yasui, Manabu Yamamoto, Kumiko Hirayama, Kunihiko Shiraki, Dirk Theisen-Kunde, Ralf Brinkmann, Yoko Miura, Takeya Kohno

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 2/2017

Abstract

Purpose

To assess retinal sensitivity after selective retina therapy (SRT) in patients with central serous chorioretinopathy (CSCR).

Methods

Seventeen eyes of 17 patients with CSCR lasting longer than 3 months were treated with SRT (wavelength 527 nm Nd: YLF laser, 50–150 μJ/pulse, spot diameter 200 μm). Measurement of best-corrected visual acuity (BCVA), optical coherence tomography, fluorescence angiography, and microperimetry (MAIA™) were conducted before, and 1 and 3 months after treatment. Microperimetry was performed in the central 10° of the macula, and at the test spots applied near the vascular arcade for energy titration. In addition to the treatment effect, all test irradiation spots were thoroughly analyzed with regard to their sensitivity changes.

Results

The mean logMAR BCVA had improved from 0.06 to 0.02 after 1 month (p = 0.11) and to 0.03 after 3 months (p = 0.003). Eleven out of 17 eyes (64.7%) showed complete resolution of subretinal fluid after 3 months. Retinal sensitivity in the central 10° increased after 1 month (median: 25.9 dB) and 3 months (26.6 dB) as compared with that before treatment (23.0 dB) (p < 0.001). Analysis of the test spots revealed a slight decrease in retinal sensitivity after 1 month (ΔdB = −0.5 ± 2.1, p = 0.006), while there was no significant difference from baseline after 3 months (ΔdB = −0.3 ± 2.2, p = 0.09). No correlation was found between laser energy and the change in focal retinal sensitivity.

Conclusions

Results suggest that SRT is a safe and effective treatment for persistent CSCR and does not leave permanent scotoma regardless of irradiation energy in the therapeutic range.

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Title: Retinal sensitivity after selective retina therapy (SRT) on patients with central serous chorioretinopathy
Authors: Ayako Yasui
Manabu Yamamoto
Kumiko Hirayama
Kunihiko Shiraki
Dirk Theisen-Kunde
Ralf Brinkmann
Yoko Miura
Takeya Kohno
Publication date: 01-02-2017
Publisher: Springer Berlin Heidelberg
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 2/2017
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-016-3441-8

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Retinal sensitivity after selective retina therapy (SRT) on patients with central serous chorioretinopathy

Abstract

Purpose

Methods

Results

Conclusions

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Abstract

Purpose

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Results

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