Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Graefe's Archive for Clinical and Experimental Ophthalmology
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology 10/2015

01-10-2015 | Pediatrics

Strabismus in infants following congenital cataract surgery

Authors: Elif Demirkilinc Biler, Duygu Inci Bozbiyik, Onder Uretmen, Suheyla Kose

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 10/2015

Login to get access

Abstract

Purpose

This study aimed to determine the incidence and characteristics of strabismus following congenital cataract surgery in infants.

Materials and methods

Patients aged <12 months who underwent surgery for congenital cataract and were followed-up for ≥1 years were included. Patients that had strabismus prior to surgery were excluded. Data regarding gender, cataract laterality, morphology, and density, age at the time of cataract surgery, ocular motility post surgery, and the presence of nystagmus were retrospectively obtained from the patients’ records.

Results

The study included 79 patients (48 male and 31 female). Unilateral surgery was performed in 14 of the patients, versus bilateral surgery in 65. Strabismus did not occur post surgery in 32 (40.5 %) of the patients (group 1), whereas 47 (59.5 %) (group 2) developed strabismus following surgery. The patients in group 1 were followed-up for a mean 50.7 ± 38.5 months, versus 50.3 ± 39 months in group 2. Mean age at the time of cataract surgery in groups 1 and 2 was 3.6 ± 1.9 years and 4.6 ± 3.2 months respectively. Mean duration of time between cataract surgery and the development of strabismus was 13.3 ± 13 months (range: 1–60 months). Unilateral cases were more prone to develop strabismus, which was statistically significant (p = 0.028). Age at the time of cataract surgery, gender, cataract density, the occurrence of aphakic glaucoma, the presence of nystagmus, and additional ocular surgery were not significantly associated with the development of strabismus.

Conclusion

Strabismus develops more frequently in children undergoing cataract surgery. In the present study strabismus occurred in more of the patients that underwent unilateral surgery. Based on the present findings, we think that long-term careful follow-up to monitor the development of strabismus is required in all infants undergoing cataract surgery, especially unilateral cases.
Literature
1.
2.
3.
Hiles DA, Sheridan SJ (1977) Strabismus associated with infantile cataracts. Int Ophthalmol Clin 17:193–202PubMed
4.
France TD, Frank JW (1984) The association of strabismus and aphakia in children. J Pediatr Ophthalmol Strabismus 21:223–226PubMed
5.
Lambert SR, Lynn M, Drews-Botsch C et al (2001) A comparison of grating visual acuity, strabismus, and reoperation outcomes among children with aphakia and pseudophakia after unilateral cataract surgery during the first six months of life. J AAPOS 5:70–75CrossRefPubMed
6.
Parks MM, Johnson DA, Reed GW (1993) Long-term visual results and complications in children with aphakia. A function of cataract type. Ophthalmology 100:826–840, discussion 840–41CrossRefPubMed
7.
Park SH, Na JH, Shin SY (2010) Strabismus following bilateral cataract surgery in childhood. Jpn J Ophthalmol 54:272–277CrossRefPubMed
8.
Merino P, Gómez-de-Liaño P, Gil MR et al (2007) Strabismus and congenital cataracts. Arch Soc Esp Oftalmol 82:623–628CrossRefPubMed
9.
Birch EE, Cheng C, Stager DR Jr, Weakley DR Jr, Stager DR (2009) The critical period for surgical treatment of dense congenital bilateral cataracts. J AAPOS 13:67–71PubMedCentralCrossRefPubMed
10.
Lesueur LC, Arne JL, Chapotot EC, Thouvenin D, Malecaze F (1998) Visual outcome after paediatric cataract surgery: is age a major factor? Br J Ophthalmol 82:1022–1025PubMedCentralCrossRefPubMed
11.
Abadi RV, Forster JE, Lloyd IC (2006) Ocular motor outcomes after bilateral and unilateral infantile cataracts. Vision Res 46:940–952CrossRefPubMed
12.
Weisberg OL, Sprunger DT, Plager DA, Neely DE, Sondhi N (2005) Strabismus in pediatric pseudophakia. Ophthalmology 112(9):1625–1628CrossRefPubMed
13.
Greenberg AE, Mohney BG, Diehl NN, Burke JP (2007) Incidence and types of childhood esotropia: a population-based study. Ophthalmology 114(1):170–174CrossRefPubMed
14.
Govindan M, Mohney BG, Diehl NN, Burke JP (2005) Incidence and types of childhood exotropia: a population-based study. Ophthalmology 112(1):104–108CrossRefPubMed
15.
Kornder LD, Nursey JN, Pratt-Johnson JA, Beattie A (1974) Detection of manifest strabismus in young children. 2. A retrospective study. Am J Ophthalmol 77:211–214CrossRefPubMed
16.
Friedman Z, Neumann E, Hyams SW, Peleg B (1980) Ophthalmic screening of 38,000 children, age 1 to 2½ years, in child welfare clinics. J Pediatr Ophthalmol Strabismus 17:261–267PubMed
17.
Spanou N, Alexopoulos L, Manta G, Tsamadou D, Drakos H, Paikos P (2011) Strabismus in pediatric lens disorders. J Pediatr Ophthalmol Strabismus 48:163–166CrossRefPubMed
18.
Magli A, Iovine A, Bruzzese D, Giani U, Fimiani F (2008) Strabismus in developmental cataract. Eur J Ophthalmol 18:540–543PubMed
19.
Bothun ED, Cleveland J, Lynn MJ, Christiansen SP, Vanderveen DK, Neely DE, Kruger SJ, Lambert SR (2013) Infant Aphakic Treatment Study. One-year strabismus outcomes in the Infant Aphakia Treatment Study. Ophthalmology 120(6):1227–1231PubMedCentralCrossRefPubMed
20.
Watts P, Abdolell M, Levin AV (2003) Complications in infants undergoing surgery for congenital cataract in the first 12 weeks of life: is early surgery better? J AAPOS 7(2):81–85CrossRefPubMed
21.
22.
23.
Lundvall A, Kugelberg U (2002) Outcome after treatment of congenital bilateral cataract. Acta Ophthalmol Scand 80(6):593–597CrossRefPubMed
24.
Hussin HM, Markham R (2009) Long-term visual function outcomes of congenital cataract surgery with intraocular lens implantation in children under 5 years of age. Eur J Ophthalmol 19(5):754–761PubMed
25.
26.
Wright KW, Christensen LE, Noguchi BA (1992) Results of late surgery for presumed congenital cataracts. Am J Ophthalmol 114(4):409–415CrossRefPubMed
27.
Ye H, Deng D, Qian Y, Lin Z, Chen W (2007) Long-term visual outcome of dense bilateral congenital cataract. Chin Med J 120(17):1494–1497PubMed
28.
Birch EE, Wang J, Felius J, Stager DR, Hertle RW (2012) Fixation control and eye alignment in children treated for dense congenital or developmental cataracts. J AAPOS 16:156–160PubMedCentralCrossRefPubMed
29.
Gelbart SS, Hoyt CS, Jasterbski G, Marg E (1982) Long term visual results in bilateral congenital cataracts. Am J Ophthalmol 93:615–621CrossRefPubMed
30.
Hosal BM, Biglan AW, Elhan AH (2000) High levels of binocular function are achievable after removal of monocular cataracts in children before 8 years of age. Ophthalmology 107(9):1647–1655CrossRefPubMed
Metadata
Title
Strabismus in infants following congenital cataract surgery
Authors
Elif Demirkilinc Biler
Duygu Inci Bozbiyik
Onder Uretmen
Suheyla Kose
Publication date
01-10-2015
Publisher
Springer Berlin Heidelberg
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 10/2015
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-015-2983-5

Other articles of this Issue 10/2015

Graefe's Archive for Clinical and Experimental Ophthalmology 10/2015 Go to the issue

Basic Science

Intravitreal inhibition of complement C5a reduces choroidal neovascularization in mice

Letter to the Editor

Comment on: Park SW, Byon IS, Kim HY, Lee JE, Oum BS (2015) Analysis of the ganglion cell layer and photoreceptor layer using optical coherence tomography after idiopathic epiretinal membrane surgery. Graefes Arch Clin Exp Ophthalmol 253:207–14

Retinal Disorders

Quantifying silicone oil emulsification in patients: are we only seeing the tip of the iceberg?

Retinal Disorders

Subthreshold grid laser versus intravitreal bevacizumab as second-line therapy for macular edema in branch retinal vein occlusion recurring after conventional grid laser treatment

Cornea

Effects of CD25siRNA gene transfer on high-risk rat corneal graft rejection

Retinal Disorders

Intravitreal bevacizumab monotherapy for type-1 prethreshold, threshold, and aggressive posterior retinopathy of prematurity — 27 month follow-up results from Turkey