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Published in: Graefe's Archive for Clinical and Experimental Ophthalmology 10/2013

01-10-2013 | Miscellaneous

Extraction of retinal tacks from subjects implanted with an epiretinal visual prosthesis

Authors: Eugene de Juan Jr., Rand Spencer, Pierre-Olivier Barale, Lyndon da Cruz, Jordan Neysmith

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 10/2013

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Abstract

Background

Retinal tacks, first developed for the treatment of complex retinal detachments, have more recently been used for the fixation of epiretinal electrode arrays as part of implanted visual prostheses. Here, we report on the clinical experience of extracting four such tacks after chronic implantation. The ability to safely extract retinal tacks ensures that epiretinal devices can be repositioned or removed if necessary.

Methods

Custom-built, titanium alloy retinal tacks were mechanically removed from the posterior coats after prolonged implantation (up to 19 months). The resulting wound was characterized by clinical evaluation, fundus photography, and fluorescein angiography while being monitored for stability over time. The wounds were also compared to earlier published reports of the healing response around retinal tacks in human subjects.

Results

Tack extraction was accomplished successfully, without complication, in all four subjects. The wound site was readily identified by pale scar tissue. No change in the wound size or appearance was noted over many months of post-operative observation (up to 22 months after explant). No adverse effects on overall ocular health were detected.

Conclusion

Extraction of retinal tacks from subjects implanted with epiretinal prostheses can be performed without significant complication. The long-term healing response appears to be stable and localized in eyes afflicted with retinitis pigmentosa or choroideremia. There was also minimal, if any, impact on the local circulatory system. These cases suggest that the use of retinal tacks for anchoring epiretinal visual prostheses does not preclude safe repositioning or removal of the device more than a year after implant.
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Metadata
Title
Extraction of retinal tacks from subjects implanted with an epiretinal visual prosthesis
Authors
Eugene de Juan Jr.
Rand Spencer
Pierre-Olivier Barale
Lyndon da Cruz
Jordan Neysmith
Publication date
01-10-2013
Publisher
Springer Berlin Heidelberg
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 10/2013
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-013-2452-y

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