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Graefe's Archive for Clinical and Experimental Ophthalmology

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Open Access 01-10-2013 | Ophthalmology

Reduction in choroidal thickness of macular area in polypoidal choroidal vasculopathy patients after intravitreal ranibizumab therapy

Authors: Tadayuki Nishide, Natsuki Hayakawa, Misako Nakanishi, Mai Ishii, Shinya Okazaki, Ikuko Kimura, Etsuko Shibuya, Nobuhisa Mizuki

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 10/2013

Abstract

Background

To evaluate changes in retinal and choroidal thickness changes after three intravitreal ranibizumab (IVR) injections for polypoidal choroidal vasculopathy (PCV) using enhanced depth-imaging-optical coherence tomography (EDI-OCT).

Methods

In this retrospective, observational case series, EDI-OCT was used to measure changes in choroidal thickness at nine points in a lattice shape in the macula before and after introductory-stage IVR.

Results

Choroidal thickness was decreased at all nine points in the lattice shape, but was significantly decreased only at the fovea.

Conclusion

The subfoveal choroidal thickness may be reduced by introductory-stage IVR in patients with PCV. In particular, choroidal thickness at the fovea was reduced during the early stage of treatment.

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Title: Reduction in choroidal thickness of macular area in polypoidal choroidal vasculopathy patients after intravitreal ranibizumab therapy
Authors: Tadayuki Nishide
Natsuki Hayakawa
Misako Nakanishi
Mai Ishii
Shinya Okazaki
Ikuko Kimura
Etsuko Shibuya
Nobuhisa Mizuki
Publication date: 01-10-2013
Publisher: Springer Berlin Heidelberg
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 10/2013
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-013-2419-z

At a glance: The STEP trials

Springer Medicine

Reduction in choroidal thickness of macular area in polypoidal choroidal vasculopathy patients after intravitreal ranibizumab therapy

Abstract

Background

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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