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Graefe's Archive for Clinical and Experimental Ophthalmology
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology 12/2009

01-12-2009 | Review Article

Silicone oil induced glaucoma: A review

Authors: Parul Ichhpujani, Anjana Jindal, L. Jay Katz

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 12/2009

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Abstract

Background

Silicone oil has been an important adjunct for internal tamponade in the treatment of complicated retinal detachment for the past 4 decades. A known complication of its use has been the development of secondary glaucoma.

Methods

This article reviews the current body of literature documenting the different pathogeneses, predisposing factors and management of silicone oil induced pressure elevation and optic neuropathy. Categorization is clarified for the different types of secondary glaucomas due to silicone oil.

Results

Four different mechanisms have been proposed for the pathogenesis of glaucoma that require different therapeutic strategies: (1) overfill with total anterior chamber fill leads to an open-angle glaucoma due to mechanical obstruction of outflow, (2) pupillary block with silicone oil incites angle closure glaucoma, (3) denaturation of silicone oil into microdroplets may sweep into the trabecular meshwork with the development of secondary open angle glaucoma, or (4) finally, inflammation or exacerbation of pre-existing glaucoma.

Conclusion

Understanding the risk factors and the pathogenesis of secondary glaucoma when using silicone oil helps guide the timely and appropriate course of treatment.
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Metadata
Title
Silicone oil induced glaucoma: A review
Authors
Parul Ichhpujani
Anjana Jindal
L. Jay Katz
Publication date
01-12-2009
Publisher
Springer-Verlag
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 12/2009
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-009-1155-x

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