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Graefe's Archive for Clinical and Experimental Ophthalmology
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology 11/2009

01-11-2009 | Retinal Disorders

Heavy silicone oil (Densiron-68) for the treatment of persistent macular holes

Densiron-68 Endotamponade for Persistent Macular Holes

Authors: Stanislao Rizzo, Federica Genovesi-Ebert, Andrea Vento, Federica Cresti, Sofia Miniaci, Maria Chiara Romagnoli

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 11/2009

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Abstract

Purpose

To evaluate the efficacy and safety of the use of Densiron-68 as intraocular endotamponade for the treatment of persisting macular holes (persistent MHs).

Methods

Retrospective interventional case study on 23 consecutive eyes showing persistent MHs after unsuccessful primary surgery that underwent retreatment with pars plana vitrectomy and Densiron-68 filling. The main outcome measures were: anatomic closure evaluated with optical coherence tomography (OCT), final best-corrected visual acuity (BCVA), and postoperative complications.

Results

A total of 23 patients (52–88 years) were studied. Pre-operative OCT showed full-thickness MH (mean size 560 µm) in all patients. Densiron-68 was left in situ for 1.5–3 months. Final follow-up time was 12 months after the last surgery. Postoperative OCT showed the complete closure of the PMH in 20 of 23 eyes. Pre-operative BCVA ranged from 20/200 to 20/630 (1.50–1.00 logMAR, mean 1.14). Final postoperative BCVA ranged from 20/30 to 20/400 (0.18–1.30 logMAR, mean. 0.61). Nineteen eyes (82%) showed a significant increase in visual acuity by at least three lines: 11 (47%) patients gained at least four lines. Three eyes remained unchanged (13%). One case deteriorated by two lines (4%). No major complications were recorded.

Conclusions

Retreatment with Densiron-68 filling was safe and achieved encouraging anatomic and functional results.
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Metadata
Title
Heavy silicone oil (Densiron-68) for the treatment of persistent macular holes
Densiron-68 Endotamponade for Persistent Macular Holes
Authors
Stanislao Rizzo
Federica Genovesi-Ebert
Andrea Vento
Federica Cresti
Sofia Miniaci
Maria Chiara Romagnoli
Publication date
01-11-2009
Publisher
Springer-Verlag
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 11/2009
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-009-1131-5

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