Published in:
Open Access
01-08-2019 | CAR T-Cell Therapy | Journal club
Neurotoxicity of novel cancer immunotherapies
Authors:
M. D. Willis, N. P. Robertson
Published in:
Journal of Neurology
|
Issue 8/2019
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Excerpt
Novel immunotherapies are emerging as an exciting treatment for a variety of haematological and solid malignancies. Chimeric antigen receptor (CAR) T cells and immune checkpoint inhibitors (ICPI) are the two classes of treatment currently available. Despite very promising oncological outcomes for these treatments, neurotoxicity has emerged as a serious adverse event. With a growing number of oncological indications, clinicians now need to be aware of the neurological side effects of these therapies. …