Top

Journal of Neurology

Published in:

01-09-2018 | Letter to the Editors

Telomere length as a modifier of age-at-onset in Huntington disease: a two-sample Mendelian randomization study

Authors: N. Ahmad Aziz, Patrick Weydt

Published in: Journal of Neurology | Issue 9/2018

Excerpt

Dear Sirs, …

GeM-HD Consortium (2015) Identification of genetic factors that modify clinical onset of Huntington’s disease. Cell 162(3):516–526CrossRef

Kota LN, Bharath S, Purushottam M et al (2015) Reduced telomere length in neurodegenerative disorders may suggest shared biology. J Neuropsychiatry Clin Neurosci 27(2):e92–e96CrossRefPubMed

Zhan Y, Song C, Karlsson R et al (2015) Telomere length shortening and Alzheimer disease—a Mendelian randomization study. JAMA Neurol 72(10):1202–1203CrossRefPubMed

Davey Smith G, Hemani G (2014) Mendelian randomization: genetic anchors for causal inference in epidemiological studies. Hum Mol Genet 23(R1):R89–R98CrossRefPubMedPubMedCentral

Codd V, Nelson CP, Albrecht E et al (2013) Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet 45(4):422–427CrossRefPubMedPubMedCentral

Hemani G, Zheng J, Wade KH et al (2016) MR-base: a platform for systematic causal inference across the phenome using billions of genetic associations. bioRxiv. https://doi.org/10.1101/078972 CrossRef

Title: Telomere length as a modifier of age-at-onset in Huntington disease: a two-sample Mendelian randomization study
Authors: N. Ahmad Aziz
Patrick Weydt
Publication date: 01-09-2018
Publisher: Springer Berlin Heidelberg
Published in: Journal of Neurology / Issue 9/2018
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-018-8972-y

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Telomere length as a modifier of age-at-onset in Huntington disease: a two-sample Mendelian randomization study

Excerpt

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 9/2018

Long-term evolution of patient-reported outcome measures in spinocerebellar ataxias

Primary progressive freezing gait with impressive response to laser light visual cueing: a video case report

SEEG-guided radiofrequency coagulation (SEEG-guided RF-TC) versus anterior temporal lobectomy (ATL) in temporal lobe epilepsy

The effects of anodal tDCS over the supplementary motor area on gait initiation in Parkinson’s disease with freezing of gait: a pilot study

Validation of a novel Montreal Cognitive Assessment scoring algorithm in non-demented Parkinson’s disease patients

Corpus callosal involvement is correlated with cognitive impairment in multiple system atrophy