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Open Access 01-04-2018 | Original Communication

Association between marriage and outcomes in patients with acute ischemic stroke

Authors: Qi Liu, Xianwei Wang, Yilong Wang, Chunxue Wang, Xingquan Zhao, Liping Liu, Zixiao Li, Xia Meng, Li Guo, Yongjun Wang

Published in: Journal of Neurology | Issue 4/2018

Abstract

Backgrounds

The previous studies on the association between marital status and stroke outcomes were rare. Furthermore, the existing studies mostly focused on the protective effect of marriage on survival. We conducted the study to evaluate the association between marital status and adverse stroke outcomes in patients with AIS based on China national stroke registry.

Methods

This was a multicenter, prospective cohort study of patients with AIS. Patients were classified into two groups based on marital status at admission: married and unmarried. The primary outcomes included all-cause mortality, stroke recurrence, combined endpoint, and stroke disability. Stroke disability was defined as modified Rankin Scale of 2–6.

Results

Of 12,118 patients, 1220 were unmarried and 10,898 married. Unmarried patients had higher proportion of 1-year post-stroke events than married patients did. As compared with being unmarried, the adjusted odds ratios with 95% confidence interval of being married for outcomes were as follows: 0.70 (0.58–0.84) for all-cause mortality, 0.78 (0.66–0.91) for stroke recurrence, 0.77 (0.66–0.90) for combined endpoint, and 0.75 (0.65–0.88) for stroke disability. Interactions between marital status and education were significant for all outcomes except for stroke disability.

Conclusions

Marital status was associated with all adverse stroke outcomes in patients with acute ischemic stroke, especially in those with middle-school education.

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Title: Association between marriage and outcomes in patients with acute ischemic stroke
Authors: Qi Liu
Xianwei Wang
Yilong Wang
Chunxue Wang
Xingquan Zhao
Liping Liu
Zixiao Li
Xia Meng
Li Guo
Yongjun Wang
Publication date: 01-04-2018
Publisher: Springer Berlin Heidelberg
Published in: Journal of Neurology / Issue 4/2018
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-018-8793-z

At a glance: The STEP trials

Springer Medicine

Association between marriage and outcomes in patients with acute ischemic stroke

Abstract

Backgrounds

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Backgrounds

Methods

Results

Conclusions

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