Skip to main content
Top
Published in: Journal of Neurology 3/2017

01-03-2017 | Letter to the Editors

Adverse clinical outcomes after dabigatran reversal with idarucizumab to facilitate acute stroke thrombolysis

Authors: Felix C. Ng, James Bice, Anne Rodda, Matthew Lee-Archer, Douglas E. Crompton

Published in: Journal of Neurology | Issue 3/2017

Login to get access

Excerpt

Dear Sirs, …
Literature
1.
go back to reference Demaerschalk BM, Kleindorer DO, Demchuk AM, Fugate JE, Grotta JC, Khalessi AA, Levy El Palesch YY, Prabhakaran S, Saposnik G, Saver JL, Smith EE, American Heart Association Stroke Council and Council on Epidemiology and Prevention (2016) Scientific rationale for the inclusion and exclusion criteria for intravenous alteplase in acute ischemic stroke. Stroke 47:581–641CrossRefPubMed Demaerschalk BM, Kleindorer DO, Demchuk AM, Fugate JE, Grotta JC, Khalessi AA, Levy El Palesch YY, Prabhakaran S, Saposnik G, Saver JL, Smith EE, American Heart Association Stroke Council and Council on Epidemiology and Prevention (2016) Scientific rationale for the inclusion and exclusion criteria for intravenous alteplase in acute ischemic stroke. Stroke 47:581–641CrossRefPubMed
2.
go back to reference Diener HC, Bernstein R, Butcher K, Campbell B, Cloud G, Davalos A, Davis S, Ferro JM, Grond M, Krieger D, Ntaios G, Slowik A, Touzé E (2016) Thrombolysis and thrombectomy in patients treated with dabigatran with acute ischemic stroke: expert opinion. Int J Stroke 12:9–12CrossRefPubMed Diener HC, Bernstein R, Butcher K, Campbell B, Cloud G, Davalos A, Davis S, Ferro JM, Grond M, Krieger D, Ntaios G, Slowik A, Touzé E (2016) Thrombolysis and thrombectomy in patients treated with dabigatran with acute ischemic stroke: expert opinion. Int J Stroke 12:9–12CrossRefPubMed
3.
go back to reference Berrouschot J, Stoll A, Hogh T, Eschenfelder CC (2016) Intravenous thrombolysis with recombinant tissue-type plasminogen activator in a stroke patient receiving dabigatran anticoagulant after antagonization with idarucizumab. Stroke 47:1936–1938CrossRefPubMed Berrouschot J, Stoll A, Hogh T, Eschenfelder CC (2016) Intravenous thrombolysis with recombinant tissue-type plasminogen activator in a stroke patient receiving dabigatran anticoagulant after antagonization with idarucizumab. Stroke 47:1936–1938CrossRefPubMed
4.
go back to reference Pollack CV Jr, Reilly PA, Eikelboom J, Glund S, Verhamme P, Bernstein RA, Dubiel R, Huisman MV, Hylek EM, Kamphuisen PW, Kreuzer J, Levy JH, Sellke FW, Stangier J, Steiner T, Wang B, Jam CW, Weitz JI (2015) Idarucizumab for dabigatran reversal. N Engl J Med 373:511–520CrossRefPubMed Pollack CV Jr, Reilly PA, Eikelboom J, Glund S, Verhamme P, Bernstein RA, Dubiel R, Huisman MV, Hylek EM, Kamphuisen PW, Kreuzer J, Levy JH, Sellke FW, Stangier J, Steiner T, Wang B, Jam CW, Weitz JI (2015) Idarucizumab for dabigatran reversal. N Engl J Med 373:511–520CrossRefPubMed
5.
go back to reference Schmohl M, Glund S, Harada A, Imazu S, De Smet M, Moschetti V, Ramael S, Ikushima I, Grünenfelder F, Reilly P, Stangeri J (2016) Idarucizumab does not have procoagulant effects: assessment of thrombosis biomarkers in healthy volunteers. Thromb Haemost. doi:10.1160/TH16-05-0385 PubMed Schmohl M, Glund S, Harada A, Imazu S, De Smet M, Moschetti V, Ramael S, Ikushima I, Grünenfelder F, Reilly P, Stangeri J (2016) Idarucizumab does not have procoagulant effects: assessment of thrombosis biomarkers in healthy volunteers. Thromb Haemost. doi:10.​1160/​TH16-05-0385 PubMed
6.
go back to reference Schafter N, Muller A, Wullner U (2016) Systemic thrombolysis for ischemic stroke after antagonizing dabigatran with idarucizumab – a case report. J Stroke Cerebrovasc Dis 25:e126–e127CrossRef Schafter N, Muller A, Wullner U (2016) Systemic thrombolysis for ischemic stroke after antagonizing dabigatran with idarucizumab – a case report. J Stroke Cerebrovasc Dis 25:e126–e127CrossRef
8.
go back to reference Schulz JG, Kreps B (2016) Idarucizumab elimination of dabigatran minutes before systemic thrombolysis in acute ischemic stroke. J Neurol Sci 370:44CrossRefPubMed Schulz JG, Kreps B (2016) Idarucizumab elimination of dabigatran minutes before systemic thrombolysis in acute ischemic stroke. J Neurol Sci 370:44CrossRefPubMed
9.
go back to reference Mutzenbach JS, Pikija S, Otto F, Halwachs U, Weymayr F, Sellner J (2016) Intravenous thrombolysis in acute ischemic stroke after dabigatran reversal with idarucizumab–a case report. Ann Clin Transl Neurol 3:889–892CrossRefPubMedPubMedCentral Mutzenbach JS, Pikija S, Otto F, Halwachs U, Weymayr F, Sellner J (2016) Intravenous thrombolysis in acute ischemic stroke after dabigatran reversal with idarucizumab–a case report. Ann Clin Transl Neurol 3:889–892CrossRefPubMedPubMedCentral
10.
go back to reference Gawehn A, Ayari Y, Heuschkel C, Kaste M, Kermer P (2016) Successful thrombolysis with recombinant tissue plasminogen activator after antagonizing dabigatran by idarucizumab: a case report. J Med Case Rep 10:269CrossRefPubMedPubMedCentral Gawehn A, Ayari Y, Heuschkel C, Kaste M, Kermer P (2016) Successful thrombolysis with recombinant tissue plasminogen activator after antagonizing dabigatran by idarucizumab: a case report. J Med Case Rep 10:269CrossRefPubMedPubMedCentral
11.
go back to reference Zhang J, Yang Y, Sun J, Xing Y (2014) Hemorrhagic transformation after cerebral infarction: current concepts and challenges. Ann Transl Med 2:81PubMedPubMedCentral Zhang J, Yang Y, Sun J, Xing Y (2014) Hemorrhagic transformation after cerebral infarction: current concepts and challenges. Ann Transl Med 2:81PubMedPubMedCentral
12.
go back to reference Ay H, Gungor L, Arsava EM, Rosand J, Vangel M, Benner T, Schwamm LH, Furie KL, Koroshetz WJ, Sorensen AG (2010) A score to predict early risk of recurrence after ischemic stroke. Neurology 72:128–135CrossRef Ay H, Gungor L, Arsava EM, Rosand J, Vangel M, Benner T, Schwamm LH, Furie KL, Koroshetz WJ, Sorensen AG (2010) A score to predict early risk of recurrence after ischemic stroke. Neurology 72:128–135CrossRef
Metadata
Title
Adverse clinical outcomes after dabigatran reversal with idarucizumab to facilitate acute stroke thrombolysis
Authors
Felix C. Ng
James Bice
Anne Rodda
Matthew Lee-Archer
Douglas E. Crompton
Publication date
01-03-2017
Publisher
Springer Berlin Heidelberg
Published in
Journal of Neurology / Issue 3/2017
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI
https://doi.org/10.1007/s00415-017-8410-6

Other articles of this Issue 3/2017

Journal of Neurology 3/2017 Go to the issue