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Journal of Neurology
Published in: Journal of Neurology 1/2017

01-01-2017 | Review

Lesional cerebellar epilepsy: a review of the evidence

Authors: Niels A. Foit, Vera van Velthoven, Reinhard Schulz, Ingmar Blümcke, Horst Urbach, Friedrich G. Woermann, Christian G. Bien

Published in: Journal of Neurology | Issue 1/2017

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Abstract

Classical teaching in epileptology localizes the origins of focal seizures solely in the cerebral cortex, with only inhibitory effects attributed to subcortical structures. However, electrophysiological and neuroimaging studies over the last decades now provide evidence for an initiation of epileptic seizures within subcortical structures. Intrinsic epileptogenicity of hypothalamic hamartoma has already been established in recognition of subcortical epilepsy, whereas a seizure-generating impact of dysplastic cerebellar lesions remains to be clarified. Herein, we examine the supportive evidence and clinical presentation of cerebellar seizures and review therapy options.
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Metadata
Title
Lesional cerebellar epilepsy: a review of the evidence
Authors
Niels A. Foit
Vera van Velthoven
Reinhard Schulz
Ingmar Blümcke
Horst Urbach
Friedrich G. Woermann
Christian G. Bien
Publication date
01-01-2017
Publisher
Springer Berlin Heidelberg
Published in
Journal of Neurology / Issue 1/2017
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI
https://doi.org/10.1007/s00415-016-8161-9

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