Top

Journal of Neurology

Published in:

01-05-2015 | Letter to the Editors

Failure to confirm benefit of acetyl-dl-leucine in degenerative cerebellar ataxia: a case series

Authors: Johann Otto Pelz, Christopher Fricke, Dorothee Saur, Joseph Classen

Published in: Journal of Neurology | Issue 5/2015

Excerpt

Dear editors, …

Strupp M, Teufel J, Habs M, Feuerecker R, Muth C, van de Warrenburg BP et al (2013) Effects of acetyl-dl-leucine in patients with cerebellar ataxia: a case series. J Neurol 260:2556–2561PubMedCentralCrossRefPubMed

Ilg W, Synofzik M, Brotz D, Burkard S, Giese MA, Schöls L (2009) Intensive coordinative training improves motor performance in degenerative cerebellar disease. Neurology 73:1823–1830CrossRefPubMed

Miyai I, Ito M, Hattori N, Mihara M, Hatakenaka M, Yagura H et al (2012) Cerebellar ataxia rehabilitation trial in degenerative cerebellar diseases. Neurorehabil Neural Repair 26:515–522CrossRefPubMed

Gilman S, Wenning GK, Low PA, Brooks DJ, Mathias CJ, Trojanowski JQ et al (2008) Second consensus statement on the diagnosis of multiple system atrophy. Neurology 71:670–676PubMedCentralCrossRefPubMed

Schmitz-Hübsch T, Du Montcel ST, Baliko L, Berciano J, Boesch S, Depondt C et al (2006) Scale for the assessment and rating of ataxia: development of a new clinical scale. Neurology 66:1717–1720CrossRefPubMed

Weyer A, Abele M, Schmitz-Hübsch T, Schoch B, Frings M, Timmann D et al (2007) Reliability and validity of the scale for the assessment and rating of ataxia: a study in 64 ataxia patients. Mov Disord 22:1633–1637CrossRefPubMed

Hróbjartsson A, Thomsen AS, Emanuelsson F, Tendal B, Hilden J, Boutron I et al (2013) Observer bias in randomized clinical trials with measurement scale outcomes: a systematic review of trials with both blinded and nonblinded assessors. CMAJ 185:E201–E211PubMedCentralCrossRefPubMed

Vibert N, Vidal PP (2001) In vitro effects of acetyl-dl-leucine (tanganil) on central vestibular neurons and vestibulo-ocular networks of the guinea-pig. Eur J Neurosci 13:735–748CrossRefPubMed

Ferber-Viart C, Dubreuil C, Vidal PP (2009) Effects of acetyl-dl-leucine in vestibular patients: a clinical study following neurotomy and labyrinthectomy. Audiol Neurotol 14:17–25CrossRef

Title: Failure to confirm benefit of acetyl-dl-leucine in degenerative cerebellar ataxia: a case series
Authors: Johann Otto Pelz
Christopher Fricke
Dorothee Saur
Joseph Classen
Publication date: 01-05-2015
Publisher: Springer Berlin Heidelberg
Published in: Journal of Neurology / Issue 5/2015
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-015-7734-3

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Failure to confirm benefit of acetyl-dl-leucine in degenerative cerebellar ataxia: a case series

Excerpt

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 5/2015

Respiratory dysfunction in Charcot–Marie–Tooth disease type 1A

Prevalence of vestibular dysfunction in patients with vestibular schwannoma using video head-impulses and vestibular-evoked potentials

Joseph von Gerlach (1820–1896)

Redefining phenotypes associated with mitochondrial DNA single deletion

Deep brain stimulation for Alzheimer disease: a decision and cost-effectiveness analysis

The influence of previous infections and antichlamydia pneumoniae seropositivity on functional outcome in ischemic stroke patients: results from the IN2 study