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Journal of Neurology

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01-06-2013 | Letter to the Editors

Cytomegalovirus and multiple sclerosis risk

Authors: Julia Pakpoor, Jina Pakpoor, Giulio Disanto, Gavin Giovannoni, Sreeram V. Ramagopalan

Published in: Journal of Neurology | Issue 6/2013

Excerpt

Dear Sirs, …

Noseworthy JH, Lucchinetti C, Rodriguez M, Weinshenker BG (2000) Multiple sclerosis. N Engl J Med 343(13):938–952PubMedCrossRef

Ascherio A, Munger KL (2007) Environmental risk factors for multiple sclerosis. Part I: the role of infection. Ann Neurol 61(4):288–299PubMedCrossRef

Zivadinov R, Nasuelli D, Tommasi MA et al (2006) Positivity of cytomegalovirus antibodies predicts a better clinical and radiological outcome in multiple sclerosis patients. Neurol Res 28(3):262–269PubMedCrossRef

Ascherio A, Munger KL, Lennette ET et al (2001) Epstein–Barr virus antibodies and risk of multiple sclerosis: a prospective study. JAMA 286(24):3083–3088PubMedCrossRef

Buljevac D, van Doornum GJ, Flach HZ et al (2005) Epstein–Barr virus and disease activity in multiple sclerosis. J Neurol Neurosurg Psychiatry 76(10):1377–1381PubMedCrossRef

Coyle PK, Sibony PA (1987) Viral specificity of multiple sclerosis tear immunoglobulins. J Neuroimmunol 14(2):197–203PubMedCrossRef

Höllsberg P, Hansen HJ, Haahr S (2003) Altered CD8 + T cell responses to selected Epstein–Barr virus immunodominant epitopes in patients with multiple sclerosis. Clin Exp Immunol 132(1):137–143PubMedCrossRef

Hopkins RS, Indian RW, Pinnow E, Conomy J (1991) Multiple sclerosis in Galion, Ohio: prevalence and results of a case-control study. Neuroepidemiology 10(4):192–199PubMedCrossRef

Levin LI, Munger KL, O’Reilly EJ, Falk KI, Ascherio A (2010) Primary infection with the Epstein–Barr virus and risk of multiple sclerosis. Ann Neurol 67(6):824–830PubMed

10.

Martínez-Rodríguez JE, Saez-Borderías A, Munteis E, Romo N, Roquer J, López-Botet M (2010) Natural killer receptors distribution in multiple sclerosis: relation to clinical course and interferon-beta therapy. Clin Immunol 137(1):41–50PubMedCrossRef

11.

Myhr KM, Riise T, Barrett-Connor E et al (1998) Altered antibody pattern to Epstein–Barr virus but not to other herpes viruses in multiple sclerosis: a population based case-control study from western Norway. J Neurol Neurosurg Psychiatry 64(4):539–542PubMedCrossRef

12.

Pandit L, Malli C, D’Cunha A, Shetty R, Singhal B (2013) Association of Epstein–Barr virus infection with multiple sclerosis in India 325(1–2):86–89

13.

Provinciali L, Laurenzi MA, Vesprini L et al (1988) Immunity assessment in the early stages of amyotrophic lateral sclerosis: a study of virus antibodies and lymphocyte subsets. Acta Neurol Scand 78(6):449–454PubMedCrossRef

14.

Sanadgol N, Ramroodi N, Ahmadi GA et al (2011) Prevalence of cytomegalovirus infection and its role in total immunoglobulin pattern in Iranian patients with different subtypes of multiple sclerosis. New Microbiol 34(3):263–274PubMed

15.

Vartdal F, Vandvik B, Norrby E (1980) Viral and bacterial antibody responses in multiple sclerosis. Ann Neurol 8(3):248–255PubMedCrossRef

16.

Wandinger K, Jabs W, Siekhaus A et al (2000) Association between clinical disease activity and Epstein–Barr virus reactivation in MS. Neurology 55(2):178–184PubMedCrossRef

17.

Jafari N, Melles DC, Broer L, van Duijn CM, van Doornum GJJ, Hintzen RQ (2011) Higher EBV anti-early antigen IgG titres in MS patients of a Dutch genetic isolate: genes or environment? Data presented at the 5th Joint triennial congress of the European and American Committees for treatment and research in multiple sclerosis, Amsterdam, The Netherlands, 19–22 Oct 2011

18.

DeLorenze GN, Munger KL, Lennette ET, Orentreich N, Vogelman JH, Ascherio A (2006) Epstein–Barr virus and multiple sclerosis: evidence of association from a prospective study with long-term follow-up. Arch Neurol 63(6):839–844PubMedCrossRef

Title: Cytomegalovirus and multiple sclerosis risk
Authors: Julia Pakpoor
Jina Pakpoor
Giulio Disanto
Gavin Giovannoni
Sreeram V. Ramagopalan
Publication date: 01-06-2013
Publisher: Springer-Verlag
Published in: Journal of Neurology / Issue 6/2013
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-013-6912-4

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