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01-12-2009 | Letter to the editors

Irritability, psychomotor agitation and progressive insomnia induced by bilateral stimulation of the area surrounding the dorsal subthalamic nucleus (zona incerta) in Parkinson’s disease patients

Authors: Marcelo Merello, Sol Cavanagh, Santiago Perez-Lloret, Eliana Roldan, Veronica Bruno, Eduardo Tenca, Ramon Leiguarda

Published in: Journal of Neurology | Issue 12/2009

Excerpt

It has been suggested that zona incerta (ZI) stimulation can have significant positive effect on motor signs, with comparable or even better results than STN stimulation [11]. Unfortunately those reports lack cognitive and psychiatric evaluation, and no data on ZI-DBS effects of these domains, as well as on other non motor domains such as sleep, have been reported. We describe here two patients with Parkinson’s Disease (PD) suffering psychiatric complications, namely irritability, psychomotor agitation and severe progressive insomnia, as a consequence of bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN), also affecting the area surrounding the dorsal subthalamic nucleus including the ZI. …

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Title: Irritability, psychomotor agitation and progressive insomnia induced by bilateral stimulation of the area surrounding the dorsal subthalamic nucleus (zona incerta) in Parkinson’s disease patients
Authors: Marcelo Merello
Sol Cavanagh
Santiago Perez-Lloret
Eliana Roldan
Veronica Bruno
Eduardo Tenca
Ramon Leiguarda
Publication date: 01-12-2009
Publisher: D. Steinkopff-Verlag
Published in: Journal of Neurology / Issue 12/2009
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-009-5285-1

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